Concordia University

About: Concordia University is a education organization based out in Montreal, Quebec, Canada. It is known for research contribution in the topics: Context (language use) & Control theory. The organization has 13565 authors who have published 31084 publications receiving 783525 citations. The organization is also known as: Sir George Williams University & Loyola College, Montreal.

Proprioception and stability: foot position awareness as a function of age and footwear.

Abstract: We examined the hypothesis that awareness of foot position in terms of the slope of the weight-bearing surface declines with age. We further postulated that the decline would be due to a change in plantar tactile sensibility, and that footwear would further impair position judgments. We compared 15 men aged over 65 years (mean age 73) with 36 men aged under 40 (mean age 30) in terms of estimates of amplitude and direction of surface slopes. We employed a ratio scale of 0-10 representing actual slopes of 0 degrees-25 degrees in increments of 2.5 degrees. In order to examine whether subjects overestimated high angles they were told that the scale ranged from 0 to 15. We found significant differences between the two groups in terms of estimates and the effect of footwear. Psychophysical functions for estimate of slope were 0.95 for the young when barefoot and 0.71 when shod compared with 0.80 and 0.81 respectively for the older men. We conclude that sensitivity to foot position declines with age, mainly owing to loss of plantar tactile sensitivity. Footwear impairs foot position awareness in both young and old. Loss of foot position awareness may contribute to the frequency of falls in later life.

Cognitive plasticity in older adults: effects of cognitive training and physical exercise

Abstract: Cognitive training, physical activity, and exercise have often been reported to improve cognitive performance in older adults. This paper reviews some seminal and recent studies using these approaches to improve cognition and physical functioning in healthy older adults and in patients suffering from non-neurological chronic medical conditions. Results from cognitive training studies suggest that despite performance improvement in trained tasks, transfer effects appeared very limited. Surprisingly though, computerized dual-task training has been shown to improve balance and postural control in tests of physical functioning, suggesting that broad transfer can sometimes be observed. Physical exercise intervention studies generally found significant and large improvements in physical capacity, in some cognitive domains, and in quality of life. The benefits seem to be equivalent between frail and nonfrail participants. Overall, results reviewed here support the notion that cognitive plasticity for attentional control, as induced by cognitive training or physical activity and exercise, is preserved in late adulthood. Moreover, results of studies with patients at risk of cognitive decline also suggest that cognitive training and exercise interventions are promising nonpharmaceutical tools to help improve cognition in older at-risk individuals.

Elevations of nucleus accumbens dopamine and DOPAC levels during intravenous heroin self-administration.

Abstract: Extracellular dopamine and DOPAC (3,4-dihydroxyphenylacetic acid) levels in nucleus accumbens were sampled by microdialysis and quantified with high-performance liquid chromatography during intravenous heroin self-administration sessions in rats. Dopamine levels in 10 and 20 min samples were elevated following the first injection of each session, reaching a plateau of elevation within the first two or three injections and falling back toward baseline only when drug access was terminated. Elevations were in the range of 150-300% when unit dosages of 0.05-0.2 mg/kg were given. Increasing the work requirement from FR-1 to FR-10 did not appear to alter the degree of elevation of dopamine levels, and dopamine levels fell during extinction while lever-pressing rates increased 20-fold. While animals compensated for unit dose changes between 0.05 and 0.2 mg/kg/injection, adjusting their response rate such that the same hourly drug intake and the same asymptotic dopamine levels were maintained across these conditions, at 0.4 mg/kg/injection hourly drug intake and asymptotic dopamine levels were elevated beyond the levels sustained by the lower doses. These findings confirm that self-administered doses of intravenous heroin are sufficient to activate the mesolimbic dopamine system and suggest that significant heroin "craving" can emerge when dopamine levels are still moderately elevated, long before the development of dopamine depletion associated with opiate withdrawal.

Comprehensive Efficiency Modeling of Electric Traction Motor Drives for Hybrid Electric Vehicle Propulsion Applications

Abstract: Extensive research done in the recent past has proven that power electronic converters and electric propulsion motors are extremely critical components for modern hybrid electric vehicle (HEV) propulsion applications. Therefore, it is essential that both the traction motor and the associated drive operate at their optimal efficiencies throughout the driving schedule. In typical HEV propulsion applications, the traction motor and the drive are used over the entire torque/speed operational range. In view of this fact, this paper aims at modeling the inverter and motor losses/efficiencies over typical city and highway driving schedules. The noteworthy losses within a typical three-phase dc/ac traction inverter, such as the switching and conduction losses for both the insulated-gate bipolar transistors and the antiparallel diodes, are modeled and simulated over the city and highway driving patterns. An induction motor (IM) is used for a medium-sized sport utility vehicle, which was modeled in the advanced vehicle simulator (ADVISOR) software. The significant IM losses that were considered in the study include the stator copper losses, rotor copper losses, and core losses. Thus, the average efficiencies of both the inverter drive and the induction traction motor are evaluated and summarized under city as well as highway driving conditions. Finally, based on the individual-model-based efficiency analysis, the overall traction motor drive system efficiency is estimated.