Concordia University

About: Concordia University is a education organization based out in Montreal, Quebec, Canada. It is known for research contribution in the topics: Control theory & Population. The organization has 13565 authors who have published 31084 publications receiving 783525 citations. The organization is also known as: Sir George Williams University & Loyola College, Montreal.

Addictive Drugs and Brain Stimulation Reward

Abstract: Direct electrical or chemical stimulation of specific brain regions can establish response habits similar to those established by natural rewards such as food or sexual contact. Cocaine, mu and delta opiates, nicotine, phencyclidine, and cannabis each have actions that summate with rewarding electrical stimulation of the medial forebrain bundle (MFB). The reward-potentiating effects of amphetamine and opiates are associated with central sites of action where these drugs also have their direct rewarding effects, suggesting common mechanisms for drug reward per se and for drug potentiation of brain stimulation reward. The central sites at which these and perhaps other drugs of abuse potentiate brain stimulation reward and are rewarding in their own right are consistent with the hypothesis that the laboratory reward of brain stimulation and the pharmacological rewards of addictive drugs are habit forming because they act in the brain circuits that subserve more natural and biologically significant rewards.

Adaptive Self-Regulation of Unattainable Goals: Goal Disengagement, Goal Reengagement, and Subjective Well-Being

Abstract: Three studies examined associations between goal disengagement, goal reengagement, and subjective well-being. In Study 1, 115 undergraduates reported on the extent to which they were able to abandon unattainable goals and reengage their efforts in alternative goals. Study 2 examined the importance of goal disengagement and goal reengagement in groups of young adults and older adults (N = 120). In Study 3, a sample of parents of children with cancer and parents of medically healthy children was examined (N = 45). The findings confirmed that goal disengagement and goal reengagement can be associated with ratings of high subjective well-being. In addition, the results showed that goal disengagement and goal reengagement can have interactive effects on subjective well-being. The importance of the findings for effective self-regulation and successful development are discussed.

Exploratory mining and pruning optimizations of constrained associations rules

Abstract: From the standpoint of supporting human-centered discovery of knowledge, the present-day model of mining association rules suffers from the following serious shortcomings: (i) lack of user exploration and control, (ii) lack of focus, and (iii) rigid notion of relationships. In effect, this model functions as a black-box, admitting little user interaction in between. We propose, in this paper, an architecture that opens up the black-box, and supports constraint-based, human-centered exploratory mining of associations. The foundation of this architecture is a rich set of constraint constructs, including domain, class, and SQL-style aggregate constraints, which enable users to clearly specify what associations are to be mined. We propose constrained association queries as a means of specifying the constraints to be satisfied by the antecedent and consequent of a mined association.In this paper, we mainly focus on the technical challenges in guaranteeing a level of performance that is commensurate with the selectivities of the constraints in an association query. To this end, we introduce and analyze two properties of constraints that are critical to pruning: anti-monotonicity and succinctness. We then develop characterizations of various constraints into four categories, according to these properties. Finally, we describe a mining algorithm called CAP, which achieves a maximized degree of pruning for all categories of constraints. Experimental results indicate that CAP can run much faster, in some cases as much as 80 times, than several basic algorithms. This demonstrates how important the succinctness and anti-monotonicity properties are, in delivering the performance guarantee.