Institution
Connolly Hospital Blanchardstown
Healthcare•Dublin, Ireland•
About: Connolly Hospital Blanchardstown is a healthcare organization based out in Dublin, Ireland. It is known for research contribution in the topics: Population & Ambulatory blood pressure. The organization has 302 authors who have published 213 publications receiving 3858 citations. The organization is also known as: James Connolly Memorial Hospital.
Topics: Population, Ambulatory blood pressure, Stroke, Vitamin D and neurology, Staphylococcus aureus
Papers published on a yearly basis
Papers
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TL;DR: It is suggested that obesity-associated asthma is facilitated by inflammation mediated by NLRP3, IL-1β and ILC3 cells, which is found in the bronchoalveolar lavage fluid of individuals with asthma.
Abstract: The mechanisms underlying the association between obesity and the development of asthma remain incompletely understood. Dale T. Umetsu and his colleagues report that the number of IL-17A+ type 3 innate lymphoid cells (ILCs) is increased in the lungs of mice fed a high-fat diet. Activation of the NLRP3 inflammasome in lung macrophages promotes IL-1β production and ILC development, and blockade of IL-1 signaling inhibits airway hyperreactivity in obese mice. As these ILCs are also found in the lungs of individuals with asthma, these results suggest that this pathway may be targeted in asthma.
507 citations
TL;DR: Recent evidence has shown that miRNAs in the circulation may reflect underlying disease states and hence serve as potential markers for disease activity.
177 citations
TL;DR: Preoperative chemotherapy for locoregional gastroesophageal adenocarcinoma increases survival compared to surgery alone and should be offered to all eligible patients.
138 citations
134 citations
TL;DR: The ABCD2 score had predictive utility in patients with TIA suspected by nonspecialists, and low scores occurred in several patients with stroke recurrences, suggesting that caution is needed before using the score in isolation.
Abstract: Background and Purpose— Transient ischemic attack (TIA) etiologic data and the ABCD2 score may improve early stroke risk prediction, but studies are required in population-based cohorts. We investigated the external validity of the ABCD2 score, carotid stenosis, and atrial fibrillation for prediction of early recurrent stroke after TIA. Methods— Patients with TIA in the North Dublin city population (N=294 529) were ascertained by using overlapping hospital and community sources. The relations between individual ABCD2 items, carotid stenosis, atrial fibrillation, and early stroke were examined. Results— In confirmed TIA cases (n=443), carotid stenosis predicted 90-day stroke (hazard ratio=2.56; 95% CI, 1.27 to 5.15, P=0.003). Stroke risk rose with increasing grade of carotid stenosis, ranging from 5.4% (95% CI, 3.3% to 8.7%) with <50% stenosis to 17.2% (95% CI, 9.7% to 29.7%) with severe stenosis/occlusion (hazard ratio=3.3; 95% CI, 1.5 to 7.4, P=0.002). In confirmed TIA cases (n=443), the ABCD2 score perf...
118 citations
Authors
Showing all 303 results
| Name | H-index | Papers | Citations |
|---|---|---|---|
| N. Bannan | 3 | 3 | 158 |
| Eoghan McCarthy | 3 | 4 | 81 |
| Kenneth Bolger | 3 | 6 | 521 |
| Bryan Paul Traynor | 3 | 3 | 30 |
| Martin Kelly | 3 | 4 | 23 |
| Seamus Sreenan | 3 | 3 | 20 |
| Brian Christopher | 3 | 6 | 29 |
| Faith Cranfield | 2 | 2 | 13 |
| Ted Keelan | 2 | 2 | 55 |
| M. Barry | 2 | 3 | 132 |
| Joss Moore | 2 | 2 | 22 |
| John O’Kelly | 2 | 5 | 13 |
| Kathleen Cahill | 2 | 3 | 66 |
| V. Parihar | 2 | 3 | 14 |
| Ola Ahmed | 2 | 2 | 8 |