Institution
Coventry University
Education•Coventry, United Kingdom•
About: Coventry University is a education organization based out in Coventry, United Kingdom. It is known for research contribution in the topics: Context (language use) & Population. The organization has 4964 authors who have published 12700 publications receiving 255898 citations. The organization is also known as: Lanchester Polytechnic & Coventry Polytechnic.
Papers published on a yearly basis
Papers
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TL;DR: A heuristic is proposed to automatically identify forecast pools, irrespective of their source or the performance criteria, and demonstrate that in various conditions it performs at least as good as alternative pools that require additional modelling decisions and better than selection or combination.
85 citations
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TL;DR: In this article, the essential oils (clove oil, Oregano oil and tea tree oil) have been incorporated in PVA/Starch based hydrogel membranes to achieve optimized anti-bacterial activity and mechanical strength.
Abstract: Wound care has come through various trials and errors with primitive cultures applying old age techniques and knowledge. Recent research has shown that the moist environment promotes wound healing than the dry. In the present research, hydrogel membranes were fabricated by esterification of polyvinyl alcohol (PVA) with starch and glutaraldehyde as a cross-linker. The essential oils (clove oil, Oregano oil and tea tree oil) have been incorporated in PVA/Starch based hydrogel membranes. The aim was to achieve optimized anti-bacterial activity and mechanical strength. The anti-bacterial testing was performed using the disc diffusion method. The maximum antibacterial activity for fabricated hydrogels was attained by addition of 0.1 mL clove oil in PVA/Starch hydrogel was 39 ± 0.57 mm and 37 ± 0.29 mm for MRSA and E. coli, respectively. The FTIR results presented the occurrence of –OH group in hydrogel membrane. The SEM results showed around dense nature of membranes with having an antibacterial agent in it or not. Mechanical examination of hydrogel membranes presented suitable tensile strength of 19.36 MPa for 0.1 mL Clove oil. Furthermore, water vapour transmission rate (WVTR) and moisture retention capability (MRC) for 0.1 mL clove oil was 36.22 g/m2h and 95.50%, respectively. The experimental conclusion nominated that fabricated hydrogel articulates good antibacterial, mechanical and physical properties that it could be used in wound dressing applications. The best results were obtained for clove oil using 0.1 mL as an antibacterial agent.
85 citations
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TL;DR: The diagnosis of colorectal cancer can be difficult as symptoms are variable with poor specificity, so there is a quest for simple, non‐invasive testing that can help streamline those with significant colonic pathology.
Abstract: SummaryBackground
The diagnosis of colorectal cancer (CRC) can be difficult as symptoms are variable with poor specificity. Thus, there is a quest for simple, non-invasive testing that can help streamline those with significant colonic pathology.
Aim
To assess using faecal immunochemical test for haemoglobin (FIT) or faecal calprotectin (FCP) to detect CRC and adenoma in symptomatic patients referred from primary care.
Methods
A total of 799 referred for urgent lower gastrointestinal investigations were prospectively recruited. Of these, 430 completed colonic investigations and returned stool samples, and were included in the final statistical analysis. Faecal immunochemical test for haemoglobin was performed on HM-JACKarc analyser (Kyowa Medex, Tokyo, Japan), and FCP by the EliA Calprotectin immunoassay (Thermo Fisher Scientific, Waltham, United States).
Results
The negative predictive value (NPV) using FIT alone or both markers (FIT and FCP) in combination was similar at 99% for CRC, with a sensitivity and specificity of 84% and 93%, respectively. FIT measurements were significantly higher in left-sided colonic lesions compared with the right side; 713 vs. 94; P = 0.0203). For adenoma, the NPV using FIT alone, or both markers (FIT and FCP) in combination, was similar at 94% with a sensitivity and specificity of 69% and 56%, respectively.
Conclusions
Undetectable faecal immunochemical test for haemoglobin is sufficiently sensitive to exclude colorectal cancer, with higher values in left-sided lesions. FCP in combination does not appear to provide additional diagnostic information. Further studies to determine the health economic benefits of implementing faecal immunochemical test for haemoglobin in primary care are required.
85 citations
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TL;DR: Differential pulse voltammetry (DPV) of NE at the modified electrode exhibited two linear dynamic ranges with a detection limit (3σ) of 77±2 nM, and DPV was used for simultaneous determination of NE, AC and Trp at themodified electrode, and quantitation of NE in some real samples by the standard addition method.
85 citations
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TL;DR: It is concluded that the homogenization of these fields represents the current challenge for the engineer and the materials scientist.
85 citations
Authors
Showing all 5097 results
Name | H-index | Papers | Citations |
---|---|---|---|
Xiang Zhang | 154 | 1733 | 117576 |
Zidong Wang | 122 | 914 | 50717 |
Stephen Joseph | 95 | 485 | 45357 |
Andrew Smith | 87 | 1025 | 34127 |
John F. Allen | 79 | 401 | 23214 |
Craig E. Banks | 77 | 569 | 27520 |
Philip L. Smith | 75 | 291 | 24842 |
Tim H. Sparks | 69 | 315 | 19997 |
Nadine E. Foster | 68 | 320 | 18475 |
Michael G. Burton | 66 | 519 | 16736 |
Sarah E Lamb | 65 | 395 | 28825 |
Michael Gleeson | 65 | 234 | 17603 |
David Alexander | 65 | 520 | 16504 |
Timothy J. Mason | 65 | 225 | 15810 |
David S.G. Thomas | 63 | 228 | 14796 |