Coventry University

About: Coventry University is a education organization based out in Coventry, United Kingdom. It is known for research contribution in the topics: Population & Higher education. The organization has 4964 authors who have published 12700 publications receiving 255898 citations. The organization is also known as: Lanchester Polytechnic & Coventry Polytechnic.

Understanding attribution of blame in cases of rape: An analysis of participant gender, type of rape and perceived similarity to the victim

Abstract: This study examined a variety of factors that may influence attributions towards rape victims A total of 156 participants completed a questionnaire, which included a measure of attitudes towards rape victims and a vignette depicting one of three rape scenarios (a stranger rape, date rape and seduction rape) Participants rated the extent to which they blamed the rape victim as well as the degree to which they identified with the victim and perpetrator Results indicated that male participants blamed the victim to a greater extent than did female participants, with participants consistently attributing most blame to the victim in the seduction rape scenario, then the date rape scenario, and finally the stranger rape scenario Perceptions of similarity to the rape victim and perpetrator were correlated negatively with attributions of blame These findings have important implications for juror selection, jury decision-making and attempts to improve the conviction rate in rape cases

Iron and liver fibrosis: Mechanistic and clinical aspects.

Abstract: Liver fibrosis is characterised by excessive deposition of extracellular matrix that interrupts normal liver functionality. It is a pathological stage in several untreated chronic liver diseases such as the iron overload syndrome hereditary haemochromatosis, viral hepatitis, alcoholic liver disease, non-alcoholic fatty liver disease, non-alcoholic steatohepatitis and diabetes. Interestingly, regardless of the aetiology, iron-loading is frequently observed in chronic liver diseases. Excess iron can feed the Fenton reaction to generate unquenchable amounts of free radicals that cause grave cellular and tissue damage and thereby contribute to fibrosis. Moreover, excess iron can induce fibrosis-promoting signals in the parenchymal and non-parenchymal cells, which accelerate disease progression and exacerbate liver pathology. Fibrosis regression is achievable following treatment, but if untreated or unsuccessful, it can progress to the irreversible cirrhotic stage leading to organ failure and hepatocellular carcinoma, where resection or transplantation remain the only curative options. Therefore, understanding the role of iron in liver fibrosis is extremely essential as it can help in formulating iron-related diagnostic, prognostic and treatment strategies. These can be implemented in isolation or in combination with the current approaches to prepone detection, and halt or decelerate fibrosis progression before it reaches the irreparable stage. Thus, this review narrates the role of iron in liver fibrosis. It examines the underlying mechanisms by which excess iron can facilitate fibrotic responses. It describes the role of iron in various clinical pathologies and lastly, highlights the significance and potential of iron-related proteins in the diagnosis and therapeutics of liver fibrosis.

Assessing tsunami vulnerability, an example from Herakleio, Crete

Abstract: . Recent tsunami have caused massive loss of life, destruction of coastal infrastructures and disruption to economic activity. To date, tsunami hazard studies have concentrated on determining the frequency and magnitude of events and in the production of simplistic flood maps. In general, such maps appear to have assumed a uniform vulnerability of population, infrastructure and business. In reality however, a complex set of factors interact to produce a pattern of vulnerability that varies spatially and temporally. A new vulnerability assessment approach is described, that incorporates multiple factors (e.g. parameters relating to the natural and built environments and socio-demographics) that contribute to tsunami vulnerability. The new methodology is applied on a coastal segment in Greece and, in particular, in Crete, westof the city of Herakleio. The results are presented within a Geographic Information System (GIS). The application of GIS ensures the approach is novel for tsunami studies, since it permits interrogation of the primary database by several different end-users. For example, the GIS may be used: (1) to determine immediate post-tsunami disaster response needs by the emergency services; (2) to preplan tsunami mitigation measures by disaster planners; (3) as a tool for local planning by the municipal authorities or; (4) as a basis for catastrophe modelling by insurance companies. We show that population density varies markedly with the time of the year and that 30% of buildings within the inundation zone are only single story thus increasing the vulnerability of their occupants. Within the high inundation depth zone, 11% of buildings are identified as in need of reinforcement and this figure rises to 50% within the medium inundation depth zone. 10% of businesses are located within the high inundation depth zone and these may need to consider their level of insurance cover to protect against primary building damage, contents loss and business interruption losses.