Coventry University

About: Coventry University is a education organization based out in Coventry, United Kingdom. It is known for research contribution in the topics: Context (language use) & Population. The organization has 4964 authors who have published 12700 publications receiving 255898 citations. The organization is also known as: Lanchester Polytechnic & Coventry Polytechnic.

Sliding mode state observation for non-linear systems

Abstract: In this paper a class of non-linear systems with uncertainty and a Lipschitz part is considered. The non-linear part satisfies the Lipschitz condition, whilst the uncertain part is a bounded function. A sliding mode observer is designed to yield feedforward compensation input to stabilize the error estimation system with and without a Lipschitz non-linearity. Sufficient conditions for stability of the Thau observer are also proposed. These conditions ensure the stability of the non-linear observer by selecting a suitable observer gain matrix. In general, when the system contains unmatched uncertainty, ultimate boundedness is obtained. The ultimate boundedness radius depends upon the defined ‘distance of the unmatched uncertainty’. Some sufficient conditions may ensure the stability of a non-linear observer for systems with uncertainties.

Cancer Pain: Part 1: Pathophysiology; Oncological, Pharmacological, and Psychological Treatments: A Perspective from the British Pain Society Endorsed by the UK Association of Palliative Medicine and the Royal College of General Practitioners

Abstract: Objective. This discussion document about the management of cancer pain is written from the pain specialists' perspective in order to provoke thought and interest in a multimodal approach to the manage- ment of cancer pain, not just towards the end of life, but pain at diagnosis, as a consequence of cancer therapies, and in cancer survivors. It relates the science of pain to the clinical setting and explains the role of psychological, physical, interventional and complementary therapies in cancer pain. Methods. This document has been produced by a consensus group of relevant health care profession- als in the United Kingdom and patients' representa- tives making reference to the current body of evidence relating to cancer pain. In the first of two parts, pathophysiology, oncological, pharmacologi- cal, and psychological treatment are considered. Conclusions. It is recognized that the World Health Organization (WHO) analgesic ladder, while provid- ing relief of cancer pain towards the end of life for many sufferers worldwide, may have limitations in