Institution
Curtin University
Education•Perth, Western Australia, Australia•
About: Curtin University is a education organization based out in Perth, Western Australia, Australia. It is known for research contribution in the topics: Population & Zircon. The organization has 14257 authors who have published 48997 publications receiving 1336531 citations. The organization is also known as: WAIT & Western Australian Institute of Technology.
Topics: Population, Zircon, Poison control, Health care, Mental health
Papers published on a yearly basis
Papers
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TL;DR: Multilocus sequence analysis suggested that descendants of phage type 80/81 have acquired meticillin resistance, are re-emerging as a community-acquired meticillin-resistant S aureus (MRSA) clone, and represent a sister lineage to pandemic hospital- acquired MRSA.
263 citations
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TL;DR: The intention here is to give an up-to-date overview of Giardia and giardiasis and provide an insight into the enormous wealth of literature on the subject, as well as highlight the most important recent developments and unresolved questions.
Abstract: It is over 10 years since Meyer and Radulescu (1979) reviewed Giardia and giardiasis in Advances in Parasitology. In their introduction, they emphasized that "despite their ubiquity and antiquity, the Giardia have, until recently, been little studied". In the intervening years, Giardia has been extensively studied. The number of papers published has increased enormously, two books on the parasite have been produced (Erlandsen and Meyer, 1984; Meyer, 1990a), and an international conference on Giardia has been organized (Wallis and Hammond, 1988). Yet it is still very difficult to keep up with developments in this productive field of research and, despite all these research efforts, several fundamental questions concerning Giardia and giardiasis remain unresolved (Table 1), particularly with respect to the relationship of Giardia and disease, and the role of zoonotic transmission. Indeed, it is only recently that we have started to appreciate the clinical significance of Giardia infections in developing countries and among disadvantaged groups. Giardia is now recognized as one of the 10 major parasites of humans, being equal to ascariasis as a cause of death in the developing world (Warren, 1989; Meyer, 1990b). In developed countries, Giardia has the distinction of being the most commonly reported human intestinal parasite (Acha and Szyfres, 1987; Thompson et al., 1990a; Schantz, 1991). Regrettably, however, the range of drugs available to treat giardiasis is limited and their efficacy leaves much to be desired. There is an urgent need for new antigiardial agents, yet this search is hampered by our lack of understanding of many fundamental aspects of Giardia biochemistry and metabolism. In addition, although the application of molecular biological techniques to research on Giardia has revealed new avenues of investigation, it has also given rise to many new questions about this intriguing organism concerning its phylogenetic position, reproductive behaviour and genetic diversity.
To review Giardia and giardiasis in detail would require at least an entire volume of Advances in Parasitology. Such treatment in depth is not warranted at this time in view of the excellent book recently edited by Meyer (1990a). Our intention here is to give an up-to-date overview of Giardia and giardiasis and provide an insight into the enormous wealth of literature on the subject, as well as highlight the most important recent developments and unresolved questions.
262 citations
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TL;DR: Aging is associated with increased serum TSH concentrations, with no change in free T(4) concentrations, and the largest TSH increase is in people with the lowest TSH at baseline, which suggests that the T SH increase arises from age-related alteration in the TSH set point or reduced TSH bioactivity rather than occult thyroid disease.
Abstract: Context: In cross-sectional studies, serum TSH concentrations increase with age. This has not been examined longitudinally, and it is uncertain whether the TSH increase reflects healthy aging or occult thyroid failure. Methods: We measured serum TSH, free T4, thyroid peroxidase, and thyroglobulin antibodies in 1100 participants in the 1981 and 1994 Busselton Health Surveys and derived a reference group of 908 individuals without thyroid disease or thyroid antibodies. We examined changes in thyroid function longitudinally and, in 781 participants, explored associations with the CAPZB polymorphism rs10917469. Results: At 13 yr follow-up, mean serum TSH increased from 1.49 to 1.81 mU/liter, a change in mean TSH (ΔTSH) of 0.32 mU/liter [95% confidence interval (CI) 0.27, 0.38, P < 0.001], whereas mean free T4 concentration was unchanged (16.6 vs. 16.6 pmol/liter, P = 0.7). The TSH increase was most marked in the elderly, such that gender-adjusted ΔTSH increased by 0.08 mU/liter (95% CI 0.04, 0.11) for each de...
261 citations
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13 Apr 2010TL;DR: This paper presents the main criteria which should be considered at the stage of designing the SLA in cloud computing, and investigates the negotiation strategies between cloud provider and cloud consumer and proposes the method to maintain the trust and reliability between each of the parties involved in the negotiation process.
Abstract: Cloud computing has been a hot topic in the research community since 2007. In cloud computing, the online services are conducted to be pay-as-you-use. Service customers need not be in a long term contract with service providers. Service level agreements (SLAs) are agreements signed between a service provider and another party such as a service consumer, broker agent, or monitoring agent. Because cloud computing is a recent technology providing many services for critical business applications, reliable and flexible mechanisms to manage online contracts are very important. This paper presents the main criteria which should be considered at the stage of designing the SLA in cloud computing. Also, we investigate the negotiation strategies between cloud provider and cloud consumer and propose our method to maintain the trust and reliability between each of the parties involved in the negotiation process.
261 citations
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TL;DR: Physiotherapists perceived that neither their initial training, nor currently available professional development training, instilled them with the requisite skills and confidence to successfully address and treat the multidimensional pain presentations seen in LBP.
261 citations
Authors
Showing all 14504 results
Name | H-index | Papers | Citations |
---|---|---|---|
David Smith | 129 | 2184 | 100917 |
Christopher G. Maher | 128 | 940 | 73131 |
Mike Wright | 127 | 775 | 64030 |
Shaobin Wang | 126 | 872 | 52463 |
Mietek Jaroniec | 123 | 571 | 79561 |
John B. Holcomb | 120 | 733 | 53760 |
Simon A. Wilde | 118 | 390 | 45547 |
Jian Liu | 117 | 2090 | 73156 |
Meilin Liu | 117 | 827 | 52603 |
Guochun Zhao | 113 | 406 | 40886 |
Mark W. Chase | 111 | 519 | 50783 |
Robert U. Newton | 109 | 753 | 42527 |
Simon P. Driver | 109 | 455 | 46299 |
Peter R. Schofield | 109 | 693 | 50892 |
Gao Qing Lu | 108 | 546 | 53914 |