Institution
Curtin University
Education•Perth, Western Australia, Australia•
About: Curtin University is a education organization based out in Perth, Western Australia, Australia. It is known for research contribution in the topics: Population & Zircon. The organization has 14257 authors who have published 48997 publications receiving 1336531 citations. The organization is also known as: WAIT & Western Australian Institute of Technology.
Topics: Population, Zircon, Poison control, Health care, Mental health
Papers published on a yearly basis
Papers
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TL;DR: Encouraging sufficient levels of physical activity and reducing sedentary time can play a vital role in helping people to cope with a major stressful event, such as the COVID-19 pandemic.
Abstract: To assess whether changes in physical activity and sedentary behaviour during the COVID-19 lockdown are associated with changes in mental and physical health. Observational longitudinal study. Participants living in France or Switzerland responded to online questionnaires measuring physical activity, physical and mental health, anxiety, and depressive symptoms. Paired sample t-tests were used to assess differences in physical activity and sedentary behaviour before and during lockdown. Multiple linear regressions were used to investigate associations between changes in physical activity and changes in mental and physical health during lockdown. 267 (wave1) and 110 participants (wave2; 2 weeks later) were recruited. Lockdown resulted in higher time spent in walking and moderate physical activity (~10min/day) and in sedentary behaviour (~75min/day), compared to pre COVID-19. Increased physical activity during leisure time from week 2 to week 4 of lockdown was associated with improved physical health (β=.24, p=.002). Additionally, an increase in sedentary behaviour during leisure time was associated with poorer physical health (β=-.35, p=.002), mental health (β=-.25, p=.003), and subjective vitality (β=-.30, p=.004). Ensuring sufficient levels of physical activity and reducing sedentary time can play a vital role in helping people to cope with a major stressful event, such as the COVID-19 pandemic.
223 citations
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TL;DR: In this article, the authors provide a state-of-the-art review of mainstream studies undertaken between 2005 and 2011 within the normative built environment literature, finding that a total of 120 articles were published within this period.
223 citations
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TL;DR: Investigating the biological functions of two members of the less studied IXb subgroup of the ethylene response factor family in Arabidopsis thaliana suggests that ERF5 and ERF6 play positive but redundant roles in defense against B. cinerea and may also play a role in the antagonistic crosstalk between the JA/Et and SA signalling pathways.
Abstract: The ethylene response factor (ERF) family in Arabidopsis thaliana comprises 122 members in 12 groups, yet the biological functions of the majority remain unknown. Of the group IX ERFs, the IXc subgroup has been studied the most, and includes ERF1, ERF14 and ORA59, which play roles in plant innate immunity. Here we investigate the biological functions of two members of the less studied IXb subgroup: ERF5 and ERF6. In order to identify potential targets of these transcription factors, microarray analyses were performed on plants constitutively expressing either ERF5 or ERF6. Expression of defense genes, JA/Et-responsive genes and genes containing the GCC box promoter motif were significantly upregulated in both ERF5 and ERF6 transgenic plants, suggesting that ERF5 and ERF6 may act as positive regulators of JA-mediated defense and potentially overlap in their function. Since defense against necrotrophic pathogens is generally mediated through JA/Et-signalling, resistance against the fungal necrotroph Botrytis cinerea was examined. Constitutive expression of ERF5 or ERF6 resulted in significantly increased resistance. Although no significant difference in susceptibility to B. cinerea was observed in either erf5 or erf6 mutants, the erf5 erf6 double mutant showed a significant increase in susceptibility, which was likely due to compromised JA-mediated gene expression, since JA-induced gene expression was reduced in the double mutant. Taken together these data suggest that ERF5 and ERF6 play positive but redundant roles in defense against B. cinerea. Since mutual antagonism between JA/Et and salicylic acid (SA) signalling is well known, the UV-C inducibility of an SA-inducible gene, PR-1, was examined. Reduced inducibilty in both ERF5 and ERF6 constitutive overexepressors was consistent with suppression of SA-mediated signalling, as was an increased susceptibility to avirulent Pseudomonas syringae. These data suggest that ERF5 and ERF6 may also play a role in the antagonistic crosstalk between the JA/Et and SA signalling pathways.
223 citations
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TL;DR: In this paper, the authors used the Nd isotope data to model the mafic detrital input into sedimentary basins in northern Rodinia and found that flood basalt weathering contributed to both the high average δ 13 C of seawater in the Neoproterozoic and to the initiation of the first Sturtian Snowball Earth.
223 citations
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TL;DR: The importance of STAT3 as a potential target for cancer therapy is discussed and novel insights into various classes of existing pharmacological inhibitors of this transcription factor that can be potentially developed as anti-cancer drugs are provided.
223 citations
Authors
Showing all 14504 results
Name | H-index | Papers | Citations |
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David Smith | 129 | 2184 | 100917 |
Christopher G. Maher | 128 | 940 | 73131 |
Mike Wright | 127 | 775 | 64030 |
Shaobin Wang | 126 | 872 | 52463 |
Mietek Jaroniec | 123 | 571 | 79561 |
John B. Holcomb | 120 | 733 | 53760 |
Simon A. Wilde | 118 | 390 | 45547 |
Jian Liu | 117 | 2090 | 73156 |
Meilin Liu | 117 | 827 | 52603 |
Guochun Zhao | 113 | 406 | 40886 |
Mark W. Chase | 111 | 519 | 50783 |
Robert U. Newton | 109 | 753 | 42527 |
Simon P. Driver | 109 | 455 | 46299 |
Peter R. Schofield | 109 | 693 | 50892 |
Gao Qing Lu | 108 | 546 | 53914 |