Curtin University

About: Curtin University is a education organization based out in Perth, Western Australia, Australia. It is known for research contribution in the topics: Population & Zircon. The organization has 14257 authors who have published 48997 publications receiving 1336531 citations. The organization is also known as: WAIT & Western Australian Institute of Technology.

Changes in temperature and precipitation extremes over the Greater Horn of Africa region from 1961 to 2010

Abstract: Recent special reports on climate extremes have shown evidences of changes in the patterns of climate extremes at global, regional and local scales. Understanding the characteristics of climate extremes at regional and local levels is critical not only for the development of preparedness and early warning systems, but is also fundamental in the development of any adaptation strategies. There is still very limited knowledge regarding the past, present and future patterns of climate extremes in the Greater Horn of Africa (GHA). This study, which was supported by the World Bank Global Facility for Disaster Reduction and Recovery (WB-GFDRR) and implemented by the World Meteorological Organization, was organized in terms of three workshops with three main objectives; (1) analysis of daily rainfall and temperature extremes for ten countries in the GHA region using observed in situ data running from 1971 to 2006, (2) assessing whether the United Kingdom Met-office and Hadley centre Providing REgional Climates for Impact Studies (UK-PRECIS) modelling system can provide realistic representation of the past and present climate extremes as observed by available in situ data, and (3) studying the future regional climate extremes under different scenarios to further assess the expected changes in climate extremes. This paper, therefore, uses the outputs of these workshops and also includes post-workshop analyses to assess the changes of climate extremes within the GHA. The results showed a significant decrease in total precipitation in wet days greater than 1 mm and increasing warm extremes, particularly at night, while cold extremes are decreasing. Considering a combination of geophysical models and satellite gravimetry observations from the Gravity Recovery and Climate Experiment (GRACE) mission in the frame of GRACE daily Kalman-smoothing models, for the years 2002 to 2010, we explored a decline in total water storage variations over the GHA.

The capacity of refugia for conservation planning under climate change

Abstract: Refugia – areas that may facilitate the persistence of species during large-scale, long-term climatic change –are increasingly important for conservation planning. There are many methods for identifying refugia, but the ability to quantify their potential for facilitating species persistence (ie their “capacity”) remains elusive. We propose a flexible framework for prioritizing future refugia, based on their capacity. This framework can be applied through various modeling approaches and consists of three steps: (1) definition of scope, scale, and resolution; (2) identification and quantification; and (3) prioritization for conservation. Capacity is quantified by multiple indicators, including environmental stability, microclimatic heterogeneity, size, and accessibility of the refugium. Using an integrated, semi-mechanistic modeling technique, we illustrate how this approach can be implemented to identify refugia for the plant diversity of Tasmania, Australia. The highest-capacity climate-change refugia we...

The cysteine rich necrotrophic effector SnTox1 produced by Stagonospora nodorum triggers susceptibility of wheat lines harboring Snn1.

Abstract: The wheat pathogen Stagonospora nodorum produces multiple necrotrophic effectors (also called host-selective toxins) that promote disease by interacting with corresponding host sensitivity gene products. SnTox1 was the first necrotrophic effector identified in S. nodorum, and was shown to induce necrosis on wheat lines carrying Snn1. Here, we report the molecular cloning and validation of SnTox1 as well as the preliminary characterization of the mechanism underlying the SnTox1-Snn1 interaction which leads to susceptibility. SnTox1 was identified using bioinformatics tools and verified by heterologous expression in Pichia pastoris. SnTox1 encodes a 117 amino acid protein with the first 17 amino acids predicted as a signal peptide, and strikingly, the mature protein contains 16 cysteine residues, a common feature for some avirulence effectors. The transformation of SnTox1 into an avirulent S. nodorum isolate was sufficient to make the strain pathogenic. Additionally, the deletion of SnTox1 in virulent isolates rendered the SnTox1 mutated strains avirulent on the Snn1 differential wheat line. SnTox1 was present in 85% of a global collection of S. nodorum isolates. We identified a total of 11 protein isoforms and found evidence for strong diversifying selection operating on SnTox1. The SnTox1-Snn1 interaction results in an oxidative burst, DNA laddering, and pathogenesis related (PR) gene expression, all hallmarks of a defense response. In the absence of light, the development of SnTox1-induced necrosis and disease symptoms were completely blocked. By comparing the infection processes of a GFP-tagged avirulent isolate and the same isolate transformed with SnTox1, we conclude that SnTox1 may play a critical role during fungal penetration. This research further demonstrates that necrotrophic fungal pathogens utilize small effector proteins to exploit plant resistance pathways for their colonization, which provides important insights into the molecular basis of the wheat-S. nodorum interaction, an emerging model for necrotrophic pathosystems.

Patterns of synthetic cannabinoid use in Australia.

Abstract: INTRODUCTION AND AIMS: To assess the demographic profile, use patterns, market characteristics, reasons for first use and self-reported harms associated with use of synthetic cannabinoids in Australia. DESIGN AND METHODS: An online questionnaire was administered to a purposive sample of 316 Australian synthetic cannabinoid users [96% cannabis users, 77% male, median age 27 years, interquartile range (IQR) 23-34] who self-reported demographic and drug use characteristics. RESULTS: The median duration of synthetic cannabinoid use was 6 months (IQR 2-10), 35% reported use weekly or more often and 7% reported daily use. Reasons for first use included curiosity (50%), legality (39%), availability (23%), recreational effects (20%), therapeutic effects (9%), non-detection in standard drug screening assays (8%) and to aid the reduction or cessation of cannabis use (5%). Users reported buying a median of 3 g (IQR 3-6) and paying a median of AU$60 (IQR 37-90). Most (68%) reported at least one side-effect during their last session of use, including decreased motor co-ordination (39%), fast or irregular heartbeat (33%), dissociation (22%), dizziness (20%), paranoia (18%) and psychosis (4%). 4 respondents reported seeking help. A greater number of side-effects were reported by males, those aged 18-25 years, water pipe ('bong') users and concurrent alcohol drinkers. DISCUSSION AND CONCLUSIONS: The sample reported first using synthetic cannabinoids due to curiosity, legality, availability, effects, non-detection in drug testing and to reduce their cannabis use. Harms were widely reported yet help-seeking was minimal. Inclusion of questions regarding synthetic cannabinoids in household surveys is warranted. Language: en