Curtin University

About: Curtin University is a education organization based out in Perth, Western Australia, Australia. It is known for research contribution in the topics: Population & Zircon. The organization has 14257 authors who have published 48997 publications receiving 1336531 citations. The organization is also known as: WAIT & Western Australian Institute of Technology.

Do Vertebrate Gut Metagenomes Confer Rapid Ecological Adaptation

Abstract: During times of rapid environmental change, survival of most vertebrate populations depends on their phenomic plasticity. Although differential gene-expression and post-transcriptional processes of the host genome receive focus as the main molecular mechanisms, growing evidence points to the gut microbiota as a key driver defining hosts' phenotypes. We propose that the plasticity of the gut microbiota might be an essential factor determining phenomic plasticity of vertebrates, and that it might play a pivotal role when vertebrates acclimate and adapt to fast environmental variation. We contemplate some key questions and suggest methodological approaches and experimental designs that can be used to evaluate whether gut microorganisms provide a boost of plasticity to vertebrates' phenomes, thereby increasing their acclimation and adaptation capacity.

Reducing the health disparities of Indigenous Australians: time to change focus.

Abstract: Indigenous peoples have worse health than non-Indigenous, are over-represented amongst the poor and disadvantaged, have lower life expectancies, and success in improving disparities is limited. To address this, research usually focuses on disadvantaged and marginalised groups, offering only partial understanding of influences underpinning slow progress. Critical analysis is also required of those with the power to perpetuate or improve health inequities. In this paper, using Australia as a case example, we explore the effects of ‘White’, Anglo-Australian cultural dominance in health service delivery to Indigenous Australians. We address the issue using race as an organising principle, underpinned by relations of power. Interviews with non-Indigenous medical practitioners in Western Australia with extensive experience in Indigenous health encouraged reflection and articulation of their insights into factors promoting or impeding quality health care to Indigenous Australians. Interviews were audio-taped and transcribed. An inductive, exploratory analysis identified key themes that were reviewed and interrogated in light of existing literature on health care to Indigenous people, race and disadvantage. The researchers’ past experience, knowledge and understanding of health care and Indigenous health assisted with data interpretation. Informal discussions were also held with colleagues working professionally in Indigenous policy, practice and community settings. Racism emerged as a key issue, leading us to more deeply interrogate the role ‘Whiteness’ plays in Indigenous health care. While Whiteness can refer to skin colour, it also represents a racialized social structure where Indigenous knowledge, beliefs and values are subjugated to the dominant western biomedical model in policy and practice. Racism towards Indigenous patients in health services was institutional and interpersonal. Internalised racism was manifest when Indigenous patients incorporated racist attitudes and beliefs into their lived experience, lowering expectations and their sense of self-worth. Current health policies and practices favour standardised care where the voice of those who are marginalised is often absent. Examining the effectiveness of such models in reducing health disparities requires health providers to critically reflect on whether policies and practices promote or compromise Indigenous health and wellbeing - an important step in changing the discourse that places Indigenous people at the centre of the problem.

A Complete Sample of Ultraluminous X-Ray Source Host Galaxies

Abstract: One hundred seven ultraluminous X-ray sources (ULXs) with 0.3-10.0 keV luminosities in excess of 10{sup 39} erg s{sup -1} are identified in a complete sample of 127 nearby galaxies. The sample includes all galaxies within 14.5 Mpc above the completeness limits of both the Uppsala Galaxy Catalogue and the Infrared Astronomical Satellite survey. The galaxy sample spans all Hubble types, a four-decade range in mass, 7.5 < log (M/M{sub sun}) < 11.4, and in star formation rate, 0.0002 < SFR(M{sub sun} yr{sup -1}) {<=} 3.6. ULXs are detected in this sample at rates of one per 3.2 Multiplication-Sign 10{sup 10} M{sub sun}, one per {approx}0.5 M{sub sun} yr{sup -1} star formation rate, and one per 57 Mpc{sup 3} corresponding to a luminosity density of {approx}2 Multiplication-Sign 10{sup 37} erg s{sup -1} Mpc{sup -3}. At these rates we estimate as many as 19 additional ULXs remain undetected in fainter dwarf galaxies within the survey volume. An estimated 14 objects, or 13%, of the 107 ULX candidates are expected to be background sources. The differential ULX luminosity function shows a power-law slope {alpha} {approx} -0.8 to -2.0 with an exponential cutoff at {approx}20 Multiplication-Sign 10{sup 39} erg s{sup -1} with precise valuesmore » depending on the model and on whether the ULX luminosities are estimated from their observed numbers of counts or, for a subset of candidates, from their spectral shapes. Extrapolating the observed luminosity function predicts at most one very luminous ULX, L{sub X} {approx} 10{sup 41} erg s{sup -1}, within a distance as small as 100 Mpc. The luminosity distribution of ULXs within the local universe cannot account for the recent claims of luminosities in excess of 2 Multiplication-Sign 10{sup 41} erg s{sup -1}, requiring a new population class to explain these extreme objects.« less

Timing stability of millisecond pulsars and prospects for gravitational-wave detection

Abstract: Analysis of high-precision timing observations of an array of " 20 millisecond pulsars (a socalled “timing array”) may ultimately result in the detection of a stochastic gravitational-wave background. The feasibility of such a detection and the required duration of this type of experiment are determined by the achievable rms of the timing residuals and the timing stability of the pulsars involved. We present results of the first long-term, high-precision timing campaign on a large sample of millisecond pulsars used in gravitational-wave detection projects. We show that the timing residuals of most pulsars in our sample do not contain significant lowfrequency noise that could limit the use of these pulsars for decade-long gravitational-wave detection efforts. For our most precisely timed pulsars, intrinsic instabilities of the pulsars or the observing system are shown to contribute to timing irregularities on a five-year timescale below the 100 ns level. Based on those results, realistic sensitivity curves for planned and ongoing timing array efforts are determined. We conclude that prospects for detection of a gravitational-wave background through pulsar timing array efforts within five years to a decade are good.