Institution
Curtin University
Education•Perth, Western Australia, Australia•
About: Curtin University is a education organization based out in Perth, Western Australia, Australia. It is known for research contribution in the topics: Population & Zircon. The organization has 14257 authors who have published 48997 publications receiving 1336531 citations. The organization is also known as: WAIT & Western Australian Institute of Technology.
Topics: Population, Zircon, Poison control, Context (language use), Health care
Papers published on a yearly basis
Papers
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Georgia Institute of Technology1, National Institutes of Health2, Curtin University3, Academy of Sciences of the Czech Republic4, University of Tromsø5, Virginia Tech6, University of Helsinki7, University of Georgia8, Interdisciplinary Center for Scientific Computing9, RMIT University10, Auburn University11, SLAC National Accelerator Laboratory12, Ohio State University13, Florida State University14, Hacettepe University15, Bethel University16, Emory University17
TL;DR: A rewrite of the top-level computation driver, and concomitant adoption of the MolSSI QCARCHIVE INFRASTRUCTURE project, makes the latest version of PSI4 well suited to distributed computation of large numbers of independent tasks.
Abstract: PSI4 is a free and open-source ab initio electronic structure program providing implementations of Hartree-Fock, density functional theory, many-body perturbation theory, configuration interaction, density cumulant theory, symmetry-adapted perturbation theory, and coupled-cluster theory. Most of the methods are quite efficient, thanks to density fitting and multi-core parallelism. The program is a hybrid of C++ and Python, and calculations may be run with very simple text files or using the Python API, facilitating post-processing and complex workflows; method developers also have access to most of PSI4's core functionalities via Python. Job specification may be passed using The Molecular Sciences Software Institute (MolSSI) QCSCHEMA data format, facilitating interoperability. A rewrite of our top-level computation driver, and concomitant adoption of the MolSSI QCARCHIVE INFRASTRUCTURE project, makes the latest version of PSI4 well suited to distributed computation of large numbers of independent tasks. The project has fostered the development of independent software components that may be reused in other quantum chemistry programs.
387 citations
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TL;DR: This review will provide a novel insight into the mutational landscapes of autophagy-related genes in several human cancers, using genetic information collected from an array of cancers.
Abstract: Evolutionarily conserved across eukaryotic cells, macroautophagy (herein autophagy) is an intracellular catabolic degradative process targeting damaged and superfluous cellular proteins, organelles, and other cytoplasmic components. Mechanistically, it involves formation of double-membrane vesicles called autophagosomes that capture cytosolic cargo and deliver it to lysosomes, wherein the breakdown products are eventually recycled back to the cytoplasm. Dysregulation of autophagy often results in various disease manifestations, including neurodegeneration, microbial infections, and cancer. In the case of cancer, extensive attention has been devoted to understanding the paradoxical roles of autophagy in tumor suppression and tumor promotion. In this review, while we summarize how this self-eating process is implicated at various stages of tumorigenesis, most importantly, we address the link between autophagy and hallmarks of cancer. This would eventually provide a better understanding of tumor dependence on autophagy. We also discuss how therapeutics targeting autophagy can counter various transformations involved in tumorigenesis. Finally, this review will provide a novel insight into the mutational landscapes of autophagy-related genes in several human cancers, using genetic information collected from an array of cancers.
386 citations
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Monash University1, Royal Adelaide Hospital2, Johns Hopkins University3, Curtin University4, University of South Australia5, Flinders Medical Centre6, Austin Hospital7, University of Technology, Sydney8, Canberra Hospital9, St. Vincent's Health System10, Helsinki University Central Hospital11, Australian National University12, Princess Alexandra Hospital13, Royal Brisbane and Women's Hospital14, Griffith University15, University of Notre Dame Australia16, Wellington Hospital17, University of Melbourne18, University of Western Australia19
TL;DR: Consensus recommendations regarding safety criteria for mobilization of adult, mechanically ventilated patients in the ICU have the potential to guide ICU rehabilitation whilst minimizing the risk of adverse events.
Abstract: Introduction: The aim of this study was to develop consensus recommendations on safety parameters for mobilizing adult, mechanically ventilated, intensive care unit (ICU) patients. Methods: A systematic literature review was followed by a meeting of 23 multidisciplinary ICU experts to seek consensus regarding the safe mobilization of mechanically ventilated patients. Results: Safety considerations were summarized in four categories: respiratory, cardiovascular, neurological and other. Consensus was achieved on all criteria for safe mobilization, with the exception being levels of vasoactive agents. Intubation via an endotracheal tube was not a contraindication to early mobilization and a fraction of inspired oxygen less than 0.6 with a percutaneous oxygen saturation more than 90% and a respiratory rate less than 30 breaths/minute were considered safe criteria for in- and out-of-bed mobilization if there were no other contraindications. At an international meeting, 94 multidisciplinary ICU clinicians concurred with the proposed recommendations. Conclusion: Consensus recommendations regarding safety criteria for mobilization of adult, mechanically ventilated patients in the ICU have the potential to guide ICU rehabilitation whilst minimizing the risk of adverse events.
384 citations
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TL;DR: Magmatic and metamorphic zircons have been dated from ductilely deformed gabbroic dykes defining a dyke swarm and signifying crustal extension in the northern part of the Hengshan Complex of the North China Craton.
383 citations
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TL;DR: Because species richness for many taxa appears to recover relatively rapidly in secondary forests, conservation of secondary forests may be an effective investment in future diversity.
Abstract: As mature tropical forests are cleared, secondary forests may play an important role in the con- servation of animal species, depending on how fast animal communities recover during forest regeneration. I reviewed published studies on the recovery of animal species richness and composition during tropical forest regeneration. In 38 of the 39 data sets I examined, conversion of forest to agriculture or pasture substantially reduced species richness. Given suitable conditions for forest recovery, the species richness of the animal taxa considered can be predicted to resemble that of mature forests roughly 20-40 years after land abandonment. At least for ants and birds, however, recovery of species composition appears to take substantially longer than recovery of species richness. Because species richness for many taxa appears to recover relatively rapidly in secondary forests, conservation of secondary forests may be an effective investment in future diversity. The slower recovery of species composition indicates, however, that some species will require stands of mature forest to persist.
382 citations
Authors
Showing all 14504 results
Name | H-index | Papers | Citations |
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David Smith | 129 | 2184 | 100917 |
Christopher G. Maher | 128 | 940 | 73131 |
Mike Wright | 127 | 775 | 64030 |
Shaobin Wang | 126 | 872 | 52463 |
Mietek Jaroniec | 123 | 571 | 79561 |
John B. Holcomb | 120 | 733 | 53760 |
Simon A. Wilde | 118 | 390 | 45547 |
Jian Liu | 117 | 2090 | 73156 |
Meilin Liu | 117 | 827 | 52603 |
Guochun Zhao | 113 | 406 | 40886 |
Mark W. Chase | 111 | 519 | 50783 |
Robert U. Newton | 109 | 753 | 42527 |
Simon P. Driver | 109 | 455 | 46299 |
Peter R. Schofield | 109 | 693 | 50892 |
Gao Qing Lu | 108 | 546 | 53914 |