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Danube University Krems

EducationKrems, Niederösterreich, Austria
About: Danube University Krems is a education organization based out in Krems, Niederösterreich, Austria. It is known for research contribution in the topics: Stroke & Population. The organization has 498 authors who have published 1572 publications receiving 68797 citations.


Papers
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Journal ArticleDOI
06 Apr 2012-PLOS ONE
TL;DR: It is confirmed that leukocyte TL can increase with time even in obese people with impaired glucose metabolism, and had no substantial role in worsening of glucose tolerance in people with IGT.
Abstract: Leukocyte telomere length (TL) is considered a biomarker for biological aging. Shortened TL has been observed in many complex diseases, including type 2 diabetes (T2DM). Lifestyle intervention studies, e.g. the Diabetes Prevention Study (DPS), have shown a decrease in the incidence of T2DM by promoting healthy lifestyles in individuals with impaired glucose tolerance (IGT). Our aim was to study in the DPS the influence of the lifestyle intervention on TL. TL was measured by quantitative PCR-based method at two time points (N = 334 and 343) on average 4.5 years apart during the active intervention and post-intervention follow-up. TL inversely correlated with age. Our main finding was that TL increased in about two thirds of the individuals both in the intervention and in the control groups during follow-up; TL increased most in individuals with the shortest TL at the first measurement. TL was not associated with development of T2DM, nor did lifestyle intervention have an effect on TL. No association between insulin secretion or insulin resistance indices and TL was observed. We did not detect an association between TL and development of T2DM in the DPS participants. It could be due to all participants being overweight and having IGT at baseline, both of which have been found to be independently associated with shorter leukocyte TL in some earlier studies. TL had no substantial role in worsening of glucose tolerance in people with IGT. Our study confirms that leukocyte TL can increase with time even in obese people with impaired glucose metabolism.

71 citations

Journal ArticleDOI
06 Oct 2011-Trials
TL;DR: The PODOSA experience shows that a community orientated, personal approach for recruiting South Asian ethnic minority populations can be successful in a trial setting and it is recommended that consideration is given to cover recruitment costs associated with community engagement and other personalised approaches.
Abstract: Background: Despite the growing emphasis on the inclusion of ethnic minority patients in research, there is little published on the recruitment of these populations especially to randomised, community based, lifestyle intervention trials in the UK. Methods: We share our experience of recruitment to screening in the PODOSA (Prevention of Diabetes and Obesity in South Asians) trial, which screened 1319 recruits (target 1800) for trial eligibility. A multi-pronged recruitment approach was used. Enrolment via the National Health Service included direct referrals from health care professionals and written invitations via general practices. Recruitment within the community was carried out by both the research team and through our partnerships with local South Asian groups and organisations. Participants were encouraged to refer friends and family throughout the recruitment period. Results: Health care professionals referred only 55 potential participants. The response to written invitations via general practitioners was 5.2%, lower than reported in other general populations. Community orientated, personal approaches for recruitment were comparatively effective yielding 1728 referrals (82%) to the screening stage. Conclusions: The PODOSA experience shows that a community orientated, personal approach for recruiting South Asian ethnic minority populations can be successful in a trial setting. We recommend that consideration is given to cover recruitment costs associated with community engagement and other personalised approaches. Researchers should consider prioritising approaches that minimise interference with professionals’ work and, particularly in the current economic climate, keep costs to a minimum. The lessons learned in PODOSA should contribute to future community based trials in South Asians.

71 citations

Journal ArticleDOI
TL;DR: The retranslated scale showed excellent alignment with the original MARS, and is a reliable and valid tool for experts and stakeholders to assess the quality of health apps in German-speaking populations.
Abstract: Background: Evidence for the efficacy of mobile health applications (MHA) to foster healthy behavior, to prevent the onset of disease, to manage and cure disease as well as to assist with rehabilitation is rapidly growing. However, most mobile health apps lack efficacy data, and user star ratings in app stores are limited in their objectivity. Objective: Systematic assessments are highly needed to make pro and cons of MHA use transparent and to develop quality standards. The mobile application rating scale (MARS) is such an assessment tool, but it’s not available in German yet. This study addresses that gap. Methods: The original 19-item version of the mobile app rating scale (MARS) was forward and backward translated twice, resulting in the MARS-German (MARS-G). App description items were extended (e.g. methodological background, data handling, etc.). 104 MHA were rated twice by eight independent bilingual researchers with the German and English MARS version. The internal consistency, validity and reliability of both scales were assessed. Mokken scale analysis was used to investigate the scalability of the overall scores. Results: The retranslation did not result in differences. The properties of the MARS-G are comparable to the original English version of the scale. Internal consistency is good for all subscales: Omega ranged from .72 to .91. Correlations between the scales of the German and English version reached from r=.93 to r=.98. Scalability of MARS (H=.50) and MARS-G are (H=.48) good. Conclusions: The MARS-G is a reliable and valid tool for experts and stakeholders to assess the quality of health apps in German speaking populations. Using the overall score gives a reliable quality estimation. Further studies are needed to assess the factorial structure of MARS and MARS-German. Clinical Trial: Not needed is a translation of a questionnaire, no participants involved

70 citations

Journal ArticleDOI
TL;DR: Janowski and Tomaszewski as mentioned in this paper proposed a method to solve the problem by using the Danube University Krems (DUK) in Australia and Gdansk University of Technology (GDT).

70 citations

Journal ArticleDOI
TL;DR: Results imply that the supply of mental health care could be maintained during COVID-19 and that changes in the provision of psychotherapy vary among countries and gender.
Abstract: Psychotherapists around the world are facing an unprecedented situation with the outbreak of the novel coronavirus disease (COVID-19). To combat the rapid spread of the virus, direct contact with others has to be avoided when possible. Therefore, remote psychotherapy provides a valuable option to continue mental health care during the COVID-19 pandemic. The present study investigated the fear of psychotherapists to become infected with COVID-19 during psychotherapy in personal contact and assessed how the provision of psychotherapy changed due to the COVID-19 situation and whether there were differences with regard to country and gender. Psychotherapists from three European countries: Czech Republic (CZ, n = 112), Germany (DE, n = 130) and Slovakia (SK, n = 96), with on average 77.8% female participants, completed an online survey. Participants rated the fear of COVID-19 infection during face-to-face psychotherapy and reported the number of patients treated on average per week (in personal contact, via telephone, via internet) during the COVID-19 situation as well as (retrospectively) in the months before. Fear of COVID-19 infection was highest in SK and lowest in DE (p < 0.001) and was higher in female compared to male psychotherapists (p = 0.021). In all countries, the number of patients treated on average per week in personal contact decreased (p < 0.001) and remote psychotherapies increased (p < 0.001), with more patients being treated via internet than via telephone during the COVID-19 situation (p < 0.001). Furthermore, female psychotherapists treated less patients in personal contact (p = 0.036), while they treated more patients via telephone than their male colleagues (p = 0.015). Overall, the total number of patients treated did not differ during COVID-19 from the months before (p = 0.133) and psychotherapy in personal contact remained the most common treatment modality. Results imply that the supply of mental health care could be maintained during COVID-19 and that changes in the provision of psychotherapy vary among countries and gender.

70 citations


Authors

Showing all 514 results

NameH-indexPapersCitations
Jaakko Tuomilehto1151285210682
Massimo Zeviani10447839743
J. Tuomilehto6919719801
Manfred Reichert6769519569
Roland W. Scholz6428915387
Michael Brainin5521544194
Gerald Gartlehner5429515320
Thomas Schrefl5040310867
Charity G. Moore5017911040
Josef Finsterer48147913836
Silvia Miksch442647790
J. Tuomilehto4410711425
Heinrich Schima432495973
Reinhard Bauer402285435
Thomas Groth381865191
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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
20237
202221
2021176
2020165
2019157
2018144