Institution
Danube University Krems
Education•Krems, Niederösterreich, Austria•
About: Danube University Krems is a education organization based out in Krems, Niederösterreich, Austria. It is known for research contribution in the topics: Stroke & Population. The organization has 498 authors who have published 1572 publications receiving 68797 citations.
Papers published on a yearly basis
Papers
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TL;DR: Most of the available evidence regarding the efficacy and safety of BFRs has a high risk of bias, and it is concluded that, based on the reported adverse events in these six trials, B FRs are probably safe.
Abstract: Bach Flower Remedies are thought to help balance emotional state and are commonly recommended by practitioners for psychological problems and pain. We assessed whether Bach Flower Remedies (BFRs) are safe and efficacious for these indications by performing a systematic review of the literature. We searched MEDLINE®, Embase, AMED, and the Cochrane Library from inception until June 2008 and performed a hand-search of references from relevant key articles. For efficacy, we included all prospective studies with a control group. For safety, we also included retrospective, observational studies with more than 30 subjects. Two authors abstracted data and determined risk of bias using a recognised rating system of trial quality. Four randomised controlled trials (RCTs) and two additional retrospective, observational studies were identified and included in the review. Three RCTs of BFRs for students with examination anxiety, and one RCT of BFRs for children with attention-deficit hyperactivity disorder (ADHD) showed no overall benefit in comparison to placebo. Due to the number and quality of the studies the strength of the evidence is low or very low. We did not find any controlled prospective studies regarding the efficacy of BFRs for pain. Only four of the six studies included for safety explicitly reported adverse events. Most of the available evidence regarding the efficacy and safety of BFRs has a high risk of bias. We conclude that, based on the reported adverse events in these six trials, BFRs are probably safe. Few controlled prospective trials of BFRs for psychological problems and pain exist. Our analysis of the four controlled trials of BFRs for examination anxiety and ADHD indicates that there is no evidence of benefit compared with a placebo intervention.
53 citations
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Catholic University of the Sacred Heart1, University of Genoa2, Hannover Medical School3, Lund University4, Spanish National Research Council5, University of Padua6, Joseph Fourier University7, Danube University Krems8, University of Zagreb9, University of Paris10, Oslo University Hospital11, Russian Academy12, Haukeland University Hospital13
TL;DR: An international group of expert neurologists, experienced in BoNT treatment, met to review the literature and pool their extensive clinical experience to give practical guidance about treatment of CD with BoNT.
Abstract: Cervical dystonia is a neurological movement disorder causing abnormal posture of the head. It may be accompanied by involuntary movements which are sometimes tremulous. The condition has marked effects on patients’ self-image, and adversely affects quality of life, social relationships and employment. Botulinum neurotoxin (BoNT) is the treatment of choice for CD and its efficacy and safety have been extensively studied in clinical trials. However, current guidelines do not provide enough practical information for physicians who wish to use this valuable treatment in a real-life setting. In addition, patients and physicians may have different perceptions of what successful treatment outcomes should be. Consequently, an international group of expert neurologists, experienced in BoNT treatment, met to review the literature and pool their extensive clinical experience to give practical guidance about treatment of CD with BoNT. Eight topic headings were considered: the place of BoNT within CD treatment options; patient perspectives and desires for treatment; assessment and goal setting; starting treatment with BoNT-A; follow-up sessions; management of side effects; management of non-response; switching between different BoNT products. One rapporteur took responsibility for summarising the current literature for each topic, while the consensus statements were developed by the entire expert group. These statements are presented here along with a discussion of the background information.
53 citations
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TL;DR: A simple, time-saving, but effective method called LASSIE is proposed to formalize new guideline versions of previously formalized CPGs to provide up-to-date knowledge necessary for accomplishing the daily work of health care professionals.
52 citations
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TL;DR: It is demonstrated that vesicles adhere preferentially to monocytes and granulocytes in whole blood, while no microvesicles could be visualized on lymphocytes, and an anticoagulant-dependent increase in vesicle-cell aggregates over time is revealed.
52 citations
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09 Dec 2007TL;DR: This paper introduces a concept for designing visual analytics frameworks and tailored visual analytics systems for time and time-oriented data, and presents a number of relevant design choices.
Abstract: Time is an important data dimension with distinct characteristics that is common across many application domains. This demands specialized methods in order to support proper analysis and visualization to explore trends, patterns, and relationships in different kinds of time-oriented data. The human perceptual system is highly sophisticated and specifically suited to spot visual patterns. For this reason, visualization is successfully applied in aiding these tasks. But facing the huge volumes of data to be analyzed today, applying purely visual techniques is often not sufficient. Visual analytics systems aim to bridge this gap by combining both, interactive visualization and computational analysis. In this paper, we introduce a concept for designing visual analytics frameworks and tailored visual analytics systems for time and time-oriented data. We present a number of relevant design choices and illustrate our concept by example.
52 citations
Authors
Showing all 514 results
Name | H-index | Papers | Citations |
---|---|---|---|
Jaakko Tuomilehto | 115 | 1285 | 210682 |
Massimo Zeviani | 104 | 478 | 39743 |
J. Tuomilehto | 69 | 197 | 19801 |
Manfred Reichert | 67 | 695 | 19569 |
Roland W. Scholz | 64 | 289 | 15387 |
Michael Brainin | 55 | 215 | 44194 |
Gerald Gartlehner | 54 | 295 | 15320 |
Thomas Schrefl | 50 | 403 | 10867 |
Charity G. Moore | 50 | 179 | 11040 |
Josef Finsterer | 48 | 1479 | 13836 |
Silvia Miksch | 44 | 264 | 7790 |
J. Tuomilehto | 44 | 107 | 11425 |
Heinrich Schima | 43 | 249 | 5973 |
Reinhard Bauer | 40 | 228 | 5435 |
Thomas Groth | 38 | 186 | 5191 |