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Institution

Deakin University

EducationBurwood, Victoria, Australia
About: Deakin University is a education organization based out in Burwood, Victoria, Australia. It is known for research contribution in the topics: Population & Poison control. The organization has 12118 authors who have published 46470 publications receiving 1188841 citations. The organization is also known as: Deakin.


Papers
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Journal ArticleDOI
TL;DR: This paper examined the influence of ownership type, size, risk profile, profitability and key environmental changes on the bank efficiency using a Tobit regression and found that profit efficiency levels are well below those of cost efficiency, which suggests that the most important inefficiencies are on the revenue side.

376 citations

Journal ArticleDOI
TL;DR: The key biological features of spheroids are outlined, specifically discussing their role in EOC dissemination and chemo-response as well as providing insights into spheroid functionality.

376 citations

Journal ArticleDOI
TL;DR: This exercise assembled 40 experts to identify key questions in this field, focussing on marine megafauna, which include a broad range of birds, mammals, reptiles, and fish, and shows that the questions have broad applicability to other taxa, including terrestrial animals, flying insects, and swimming invertebrates.
Abstract: It is a golden age for animal movement studies and so an opportune time to assess priorities for future work. We assembled 40 experts to identify key questions in this field, focussing on marine megafauna, which include a broad range of birds, mammals, reptiles, and fish. Research on these taxa has both underpinned many of the recent technical developments and led to fundamental discoveries in the field. We show that the questions have broad applicability to other taxa, including terrestrial animals, flying insects, and swimming invertebrates, and, as such, this exercise provides a useful roadmap for targeted deployments and data syntheses that should advance the field of movement ecology.

375 citations

Journal ArticleDOI
TL;DR: Auranofin is a drug that is approved for the treatment of rheumatoid arthritis but is being investigated for potential therapeutic application in a number of other diseases including cancer, neurodegenerative disorders, HIV/AIDS, parasitic infections and bacterial infections.
Abstract: Drug discovery, development and registration is an expensive and time-consuming process associated with a high failure rate [Pessetto et al. (Mol Cancer Ther 12:1299–1309, 2013), Woodcock and Woosley (Annu Rev Med 59:1–12, 2008)]. Drug ‘repurposing’ is the identification of new therapeutic purposes for already approved drugs and is more affordable and achievable than novel drug discovery [Pessetto et al. (Mol Cancer Ther 12:1299–1309, 2013)]. Auranofin is a drug that is approved for the treatment of rheumatoid arthritis but is being investigated for potential therapeutic application in a number of other diseases including cancer, neurodegenerative disorders, HIV/AIDS, parasitic infections and bacterial infections [Tejman-Yarden et al. (Antimicrob Agents Chemother 57:2029–2035, 2013)]. The main mechanism of action of auranofin is through the inhibition of reduction/oxidation (redox) enzymes that are essential for maintaining intracellular levels of reactive oxygen species. Inhibition of these enzymes leads to cellular oxidative stress and intrinsic apoptosis [Pessetto et al. (Mol Cancer Ther 12:1299–1309, 2013), Fan et al. (Cell Death Dis 5:e1191, 2014), Fiskus et al. (Cancer Res 74:2520–2532, 2014), Marzano et al. (Free Radic Biol Med 42:872–881, 2007)]. Drugs such as auranofin that have already been approved for human use [Tejman-Yarden et al. (Antimicrob Agents Chemother 57:2029–2035, 2013)] can be brought into clinical use for other diseases relatively quickly and for a fraction of the cost of new drugs.

375 citations

Journal ArticleDOI
TL;DR: In this paper, the authors present global baseline estimates of mangrove soil C stocks enabling countries to begin to assess their manglove soil C stock and the emissions that might arise from manglobve deforestation.
Abstract: This research presents global baseline estimates of mangrove soil C stocks enabling countries to begin to assess their mangrove soil C stocks and the emissions that might arise from mangrove deforestation.

374 citations


Authors

Showing all 12448 results

NameH-indexPapersCitations
Patrick D. McGorry137109772092
Mary Story13552264623
Dacheng Tao133136268263
Paul Harrison133140080539
Paul Zimmet128740140376
Neville Owen12770074166
Louisa Degenhardt126798139683
David Scott124156182554
Anthony F. Jorm12479867120
Tao Zhang123277283866
John C. Wingfield12250952291
John J. McGrath120791124804
Eduard Vieta119124857755
Michael Berk116128457743
Ashley I. Bush11656057009
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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
2023162
2022676
20215,123
20204,513
20193,981
20183,543