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Institution

Deen Dayal Upadhyay Gorakhpur University

EducationGorakhpur, Uttar Pradesh, India
About: Deen Dayal Upadhyay Gorakhpur University is a education organization based out in Gorakhpur, Uttar Pradesh, India. It is known for research contribution in the topics: Thermal decomposition & Lymnaea acuminata. The organization has 1032 authors who have published 1591 publications receiving 21734 citations. The organization is also known as: Gorakhpur University.


Papers
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Journal ArticleDOI
TL;DR: Predicting the molecular model of ribonucleotide reductase (RNR), the enzyme responsible for biosynthesis of nucleotides, to screen new drugs for treatment of drug-resistant leprosy and observed that the selected drug molecules had a strong affinity towards the modelled protein RNR.

7 citations

Journal ArticleDOI
TL;DR: A. marmelos contains many diverse bioactive components in leaves, flowers, fruits, wood, root, and bark which show multiple biological activity and high therapeutic importance as discussed by the authors.
Abstract: Bel is a holy native tree of India, which has high ethnomedicinal, therapeutic, and pharmaceutical importance. Bel contains many diverse bioactive components in leaves, flowers, fruits, wood, root, and bark which show multiple biological activity and high therapeutic importance. Plant contains coumarins, marmelosin, marmesin, imperatorin, marmin, alloimperatorin, methyl ether, xanthotoxol, scoparone, scopoletin, umbelliferone, psoralen and marmelide and marmenol, aegelin, aegelenine, marmeline, dictamine, fragrine which show anticancer, antioxidant, antimicrobial, anti-plasmodial, and hepatoprotective activities. Plant possesses various polysaccharides such as galactose, arabinose, uronic acid, and L‑rhamnose. Its seed oil contains palmitic, stearic, oleic, linoleic, and linolenic acids which possess very high nutritive value. Plant also possesses very high tannin contents (9%) in fruits, pulp leaves. Tannin found in leaves as skimmianine. Marmelosin, skimmianine, and umbelliferone are therapeutically important active principles. Aegle marmelos is also a good source of gum, wound healers, carotenoids, vitamins, sugars, and nutritive oils. The plant is used to cure digestive disorders, ulcers, headache, hypertension, diabetes, constipation, and numerous other ailments. The ripe fruits are used as a laxative, while unripe Bel fruit, promotes digestion, and cures diarrhea. A. marmelos contains plant essential oil which shows chemotypic and seasonal variations. In the present review article, ethnomedicinal, therapeutic, pharmaceuticals, and insecticidal properties of A. marmelos have been described in detail.

7 citations

Journal ArticleDOI
TL;DR: In this paper, the Bianchi type III dark energy models with constant deceleration parameter are investigated and the equation of state parameter $\omega$ is found to be time dependent and its existing range for this model is consistent with the recent observations of SN Ia data, with CMBR anisotropy and galaxy clustering statistics.
Abstract: The Bianchi type III dark energy models with constant deceleration parameter are investigated. The equation of state parameter $\omega$ is found to be time dependent and its existing range for this model is consistent with the recent observations of SN Ia data, SN Ia data (with CMBR anisotropy) and galaxy clustering statistics. The physical aspect of the dark energy models are discussed.

7 citations

Journal ArticleDOI
TL;DR: It was indicated, for the first time, that injecting high doses of BaA to nibbler fish induced both hypocalcemia and hypophosphatemia, and total protein, metabolic enzymes in the liver, total cholesterol, free cholesterol, and high-density lipoprotein cholesterol levels significantly decreased in BaA-injected fish.
Abstract: It has been reported that spinal deformity was induced in developing fish by the addition of polycyclic aromatic hydrocarbons (PAHs). To examine the mechanism of the disruption of fish bone metabolism, the effect of benz[a]anthracene (BaA), a kind of PAH, on plasma calcium, inorganic phosphorus, osteoblasts, and osteoclasts was investigated in this study. We also measured several plasma components to analyze the toxicity of BaA on other metabolisms. BaA (1 or 10 ng/g body weight) was intraperitoneally injected (four times) into nibbler fish during breeding, for 10 days, and it was indicated, for the first time, that injecting high doses of BaA to nibbler fish induced both hypocalcemia and hypophosphatemia. Furthermore, in the scales of nibbler fish treated with high doses of BaA, both osteoclastic and osteoblastic marker messengerRNA (mRNA) expressions decreased. These results are a cause of disruption of bone metabolism and, perhaps, the induction of spinal deformities. In addition, we found that total protein, metabolic enzymes in the liver, total cholesterol, free cholesterol, and high-density lipoprotein cholesterol levels significantly decreased in BaA-injected fish. These results indicate that BaA may affect liver diseases and emphasize the importance of prevention of aquatic PAH pollution.

7 citations


Authors

Showing all 1045 results

NameH-indexPapersCitations
Rudra Deo Tripathi571389640
Nawal Kishore Dubey5022910796
Harikesh Bahadur Singh463077372
Souvik Maiti432375759
Ajay Singh392568464
Alok C. Gupta391314052
Suman K Mishra382404989
Gurdip Singh361575173
Ram C. Mehrotra355066259
Nidhi Gupta352664786
Ajay K. Mishra342195050
Seema Mishra33794312
Narsingh Bahadur Singh331944062
Manish Naja321103383
Maya Shankar Singh312454261
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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
20239
202216
2021118
202094
201965
201869