Deen Dayal Upadhyay Gorakhpur University

About: Deen Dayal Upadhyay Gorakhpur University is a education organization based out in Gorakhpur, Uttar Pradesh, India. It is known for research contribution in the topics: Thermal decomposition & Lymnaea acuminata. The organization has 1032 authors who have published 1591 publications receiving 21734 citations. The organization is also known as: Gorakhpur University.

Screening of Rice (Oryza sativa L.) Genotypes for Sheath Blight(Rhizoctonia solani) in changing Climate Scenario

Abstract: Out of 108 germplasm, screened under natural as well as under artificial inoculated condition, none of the entries were found immune or resistant. However, forty five entries viz., Ramkajra, Baigani black, Beni, Prasada, Narendra-118, Narendra-97, Aswani, madhuri, Sawani, IET-14807, Pant Dhan-11, Gajgour, IET-16711, Karahni, Dalkachari, Bagri, Rambli-AS, Motiforam, Ram bhog, Kaland, Aktahwa -R, Lalkawa, Tulsi, IR-36, Suggapankhi, IET-16706, basti cul-9, Aktahwa- FIO, CR-1446, Sonachoor, Aktahwa, Bansfool, Saket-4, IR-24, NDR-359, NDR-637, Pant Dhan-4, NDR- 330, Gajgour, T-182, IET-16705, Pusa-33, Akasi, IR-8, Saryukushmaha were found moderately resistant, 37 moderately susceptible and fourteen were observed susceptible. Rest of the entries showed highly susceptible reaction. Under artificial inoculated condition, out of 82 entries, none of the entry was found resistant. Only two entries viz., Baigani black and Prasada showed moderately resistant reaction, seventeen moderately susceptible and twenty seven entries susceptible. Rest of the entries was found highly susceptible.

Nanonetwork of Coordination Polymer AHMT-Ag for the Effective and Broad Spectrum Detection of 6-Mercaptopurine in Urine and Blood Serum

Abstract: Nanocrystalline coordination polymers (NCCPs) have been considered as an incredible electrochemical sensor for the effective detection of biologically dynamic drug 6-mercaptopurine (6-MP). In the present report, a significantly stable infinite arrayed coordination polymeric network was self-assembled via metal with efficient organic tecton 4-amino-3-hydrazino-5-mercapto-1,2,4,-triazole (AHMT) in which silver(I) ions are coordinated by AHMT via hydrazino and exocyclic thiol linkage to form AHMT-Ag NCCP. An efficient and highly sensitive detection of 6-MP is attained owing to eminent electron channeling via polymeric nanocrystallite pores. An effective charge transfer leads to an interface of the AHMT-Ag nano-pores and electrolyte anchored electrode via π-π electron coupling and hydrophobic interaction. The voltammogram exposes acute redox behavior of 6-MP and discloses an impeccable illustration for the AHMT-Ag facilitated oxidation of 6-MP. This unique signature was applied in voltammetric detection of 6-MP in blood serum, human urine, and pharmaceutical formulation (tablet) by a considerable high sensitivity of 0.074, 0.058, and 0.036 μA/μM and a detection limit of 87, 97, and 37 nM, respectively. Thus, the prepared AHMT-Ag NCCP can provide a valuable platform for fabrication of highly sensitive electrochemical devices to assay biologically essential drug molecules.

Mechanistic exploration of the activities of poly(lactic-co-glycolic acid)-loaded nanoparticles of betulinic acid against hepatocellular carcinoma at cellular and molecular levels.

Abstract: The effectiveness of betulinic acid (B) and PLGA loaded nanoparticles of B (Bnp) against hepatocellular carcinoma (HCC) was established and reported earlier. In continuation of our previous report,...