Deen Dayal Upadhyay Gorakhpur University

About: Deen Dayal Upadhyay Gorakhpur University is a education organization based out in Gorakhpur, Uttar Pradesh, India. It is known for research contribution in the topics: Thermal decomposition & Lymnaea acuminata. The organization has 1032 authors who have published 1591 publications receiving 21734 citations. The organization is also known as: Gorakhpur University.

Chemistry of Titanium, Zirconium and Thorium Picramates

Abstract: Picramates of titanium, zirconium and thorium are prepared by treating the aqueous sulphate, chloride and nitrate solutions with sodium picramate. Micro-analysis, colorimetry and spectrophoto- metry are used to establish the compositions (metal : ligand ratio) of these picramates as 1 : 2 (for titanium and zirconium) and 1 : 4 (for thorium). IR studies indicate H2N → Me coordination (where Me denotes the metal). A number of explosive properties of these picramates point to the fact that the zirconium picramate is thermally more stable than the picramates of titanium and thorium.

Acute Toxicity Of Euphorbia Royleana Boiss (Euphorbiaceae) latex on freshwater catfish, Heteropneustes Fossilis (Siluriformes, Heteropneustidae)

Abstract: ACUTE TOXICITY OF Euphorbia royleana Boiss (Euphorbiaceae) LATEX ON FRESHWATER CATFISH, Hetero- pneutes fossilis (Siluriformes, Heteropneustidae). ManiRam Prasad; Abhishek Kumar, Diwakar Mishra, Sunil K. Srivastav and Ajai K. Srivastav. Acta Toxicol. Argent. (2010) 18 (1): 5-9. An acute toxicity test was performed by using a four-day static renewal test to determine the LC 50 value of aqueous extract of Euphorbia royleana latex for the freshwater fish, Heteropneustes fossilis. The LC 50 values, their upper and lower confidence limits and slope functions were calculated. The LC 50 values for aqueous extract of Euphorbia royleana latex at various exposure periods were 7.758 mg/L for 24 h, 5.847 mg/L for 48 h, 4.474 mg/L for 72 h and 3.090 mg/L for 96 h. The regression coefficient showed that there was significant negative correlation between exposure time and different LC values. Hence, it is concluded that the concentration to produce toxicity of latex of Euphorbia royleana is comparable and close to the concentration to produce toxicity of synthetic organophosphates pesticides for the fish H. fossilis. Therefore, adequate precautions must be taken when Euphorbia royleana latex is being used near fish- inhabited areas.

Vanillin–p-Anisidine System: Solid-State Reaction and Density Functional Theory Studies

Abstract: Vanillin reacts with p-anisidine in 1:1 molar ratio in the solid and molten states, in microwave oven and in solution. In all the cases, reaction occurred with the formation of N-(4-methoxy phenyl)–4-hydroxy-3-methoxy phenyl methanimine (NHM) and water. Single crystal X-ray analysis shows that NHM crystallizes in the chiral orthorhombic space group P212121. An optimized geometry of NHM was computed by using density functional theory. In the case of solid-state reaction, it is proposed that a thin layer of water molecules is formed at the junction of vanillin and p-anisidine which moves progressively towards vanillin as the reaction proceeds. The overall mechanism of solid-state reaction has been proposed by a model.

Patents in the Era of Genomics: An Overview

Abstract: The recent developments in biotechnology are the emerging science of “omics”- genomics, proteomics, transcriptomics and metabolomics. The state of the art sequencing technology has led to the deciphering of whole genome sequences of various microbes, plant, human and animals. The outcomes of genomics in the form of various genes, gene fragments, single nucleotide polymorphism, promoters and other regulatory sequences are a subject matter for patents based on its applications spanning agricultural, biomedical and industrial sectors. The patenting of genes and sequences is a debatable issue which has led to several controversies over recent years. With the accumulation of huge amount of sequences in various databases as a result of various genome sequencing projects worldwide, there is an immediate need for clarification of patenting genes and sequences. This review article gives an insight into patents based on development of genomics highlighting some of the patents based on deoxyribonucleic acid, genes, sequences and other related genetic material and gene technologies. Patents on single nucleotide polymorphism, stem cells, biomarkers for cancer diagnosis and treatment, microbial genes and plant genes are also discussed.