Deen Dayal Upadhyay Gorakhpur University

About: Deen Dayal Upadhyay Gorakhpur University is a education organization based out in Gorakhpur, Uttar Pradesh, India. It is known for research contribution in the topics: Thermal decomposition & Lymnaea acuminata. The organization has 1032 authors who have published 1591 publications receiving 21734 citations. The organization is also known as: Gorakhpur University.

Association of Polymorphism of Neuronal Nitric Oxide Synthase Gene with Risk to Parkinson's Disease.

Abstract: Environmental factors are implicated in aging as well as genetic predisposition-induced Parkinson’s disease (PD) pathogenesis. Wrongdoers increase oxidative stress and nitrosative burden, which eventually degenerate the nigrostriatal dopaminergic neurons. Inhibition of the expression of nitric oxide synthase (NOS), an enzyme responsible for nitric oxide (NO) biosynthesis, prevents the demise of the nigrostriatal dopaminergic neurons. Polymorphism of NOS is thus expected to alter PD susceptibility. The study therefore aimed to examine an association of neuronal NOS (nNOS) gene polymorphism with nitrite, an indicator of nitrosative load; lipid peroxidation, an index of oxidative stress and PD susceptibility. An age-matched case-control study was performed in the north Indian residents enrolled at the Neurology Department of the King George’s Medical University, Lucknow, India. While nNOS exon 29 TT variant genotype [odds ratio (OR) = 2.20, 95 % CI = 1.08–5.34, P = 0.040], combined TT and CT variants [OR = 1.68, 95 % CI = 1.05–2.69, P = 0.031] and T allele [OR = 1.58, 95 % CI = 1.10–2.28, P = 0.014] were found to be significantly associated with PD susceptibility, no association between nNOS exon 18 [OR for TT carriers = 1.97, 95 % CI = 0.89–4.20, P = 0.09 and OR for T allele = 1.35, 95 % CI = 0.94–1.93, P = 0.098] and PD risk was observed. Lipid peroxidation was augmented in all patients irrespective of their genotype. While genotype independent increase in nitrite content was observed in PD patients of exon 29 polymorphic groups, only heterozygous variant genotype of exon 18 was associated with augmentation in nitrite level as compared with respective control. The results obtained thus demonstrate that selected nNOS polymorphisms do not significantly contribute to PD risk in north Indian population.

Portland cement hydration in the presence of admixtures: black gram pulse and superplasticizer

Abstract: Effect of admixtures such as black gram pulse (BGP) and sulfonated naphthalene based superplasticizer (SP) on the hydration of Portland cement has been studied. The hydration characteristics of OPC in the presence of BGP and SP were studied with the help of non evaporable water content determinations, calorimetric method, Mossbauer spectroscopic and atomic force microscopic techniques. Results have shown that both BGP and SP get adsorbed at the surface of cement and its hydration products. The hydration of Portland cement is retarded in the presence of both the admixtures and nanosize hydration products are formed.

Occurrence of sugarcane yellow leaf virus in india

Abstract: Occurrence of sugarcane yellow leaf syndrome (SCYLV) has been reported from four states (UP, Haryana, Maharashtra, Tamil Nadu) of India The association of SCYLV was confirmed by DAC-ELISA test using polyclonal antiserum This is the first report of the occurrence of sugarcane yellow leaf virus in India

Contribution to the ecology of Indian aquatics

Abstract: A detailed account of the seasonal changes in vegetational cover, rate of biomass change and production of E. crassipes, growing under natural conditions in a perennial lake (‘Ramgarh’) of Gorakhpur (U.P.) India, is given in the present paper. The observations indicate that: