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Institution

Department of Biotechnology

GovernmentNew Delhi, India
About: Department of Biotechnology is a government organization based out in New Delhi, India. It is known for research contribution in the topics: Population & Silver nanoparticle. The organization has 4800 authors who have published 5033 publications receiving 82022 citations.


Papers
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Journal ArticleDOI
TL;DR: In this article, the spatial distribution of 16 PAHs and 8 HMs in 10 contaminated sites of Assam, a state in India, were analyzed and the results confirmed that the non-biodegradable nature of HMs made them stay in the soil for longer periods of time.

50 citations

Journal ArticleDOI
TL;DR: Current review provides a detail outlook on various molecular markers for diagnosis, prognosis and management of therapeutic response in cancer patients.

50 citations

Journal ArticleDOI
TL;DR: In this paper, the authors reported the isolation and screening of rhizospheric microflora of chickpea and their role in the biosynthesis of silver nanoparticles (AgNPs).
Abstract: BACKGROUND: This work reports the isolation and screening of rhizospheric microflora of chickpea and their role in the biosynthesis of silver nanoparticles (AgNPs). The antifungal potential of AgNPs for control of wilt disease of chickpea, caused by Fusarium oxysporum f. sp. ciceri (FOC) was evaluated in vitro and in vivo pot experiments. The effect of AgNPs on seed germination and soil community was also evaluated. RESULTS: Among microbial strains, two bacteria, Pseudomonas sp. and Achromobacter sp. and two fungi, Trichoderma sp. and Cephalosporium sp., were identified for biosynthesis of AgNPs. AgNPs were confirmed by UV‐visible spectra (λ = 420 nm) and transmission electron microscopy (TEM) with size 20–50 nm. AgNPs showed very high antifungal activity (95%) against FOC in vitro at 100 µgmL⁻¹ concentration. Pot experiments showed maximum and minimum reduction in wilt incidence over control, i.e. 73.33% for AgNPs and copper‐oxychloride (CuOCl) i.e. 26.67%, respectively. Seeds coated with AgNPs showed high germinability up to 98% and no negative impact was observed on soil community. CONCLUSION: This study demonstrated the role of AgNPs against the fungal disease of chickpea that can be extended to other diseases of chickpea and other important Indian crops. © 2018 Society of Chemical Industry

50 citations

Journal ArticleDOI
TL;DR: A series of twenty six structurally diverse α-aminophosphonates have been synthesized and evaluated for in vitro anti-leishmanial activity and cytotoxicity using the MTT assay and seven compounds exhibited anti-Leishmanian potency against the L. donovani promastigote.
Abstract: A series of twenty six structurally diverse α-aminophosphonates have been synthesized and evaluated for in vitro anti-leishmanial activity and cytotoxicity using the MTT assay. Among them, seven compounds (1–7) exhibited anti-leishmanial potency against the L. donovani promastigote with IC50 values in the low micromolar range. The structure–activity relationships were quantitatively evaluated by a statistically reliable CoMFA model with high predictive abilities (r2pred = 0.87, r2ncv = 0.985).

50 citations

Journal ArticleDOI
TL;DR: Porous cross-linked enzyme aggregates (p-CLEAs) of Saccharomyces cerevisiae invertase are reported for the first time in this article, where they were prepared by adding starch as a pore-making agent in crude invert enzyme solution and co-precipitating with invert enzymes using ammonium sulfate as a precipitating agent.

50 citations


Authors

Showing all 4812 results

NameH-indexPapersCitations
Ashok Pandey9679643038
Klaus Becker7932027494
Bansi D. Malhotra7537519419
Ashwani Kumar6670318099
Sanjay K. Banerjee6279830044
M. Michael Gromiha5635210617
Swaran J.S. Flora5526711434
Mallappa Kumara Swamy5486414508
Pulok K. Mukherjee5429610873
Mukesh Doble513649826
Jaya Narayan Sahu491579569
Pradeep Das4942610118
Jon R. Lorsch481177661
Rakesh Tuli471657497
Amit K. Goyal471575749
Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
20231
202261
2021948
2020648
2019572
2018427