Institution
Department of Biotechnology
Government•New Delhi, India•
About: Department of Biotechnology is a government organization based out in New Delhi, India. It is known for research contribution in the topics: Population & Silver nanoparticle. The organization has 4800 authors who have published 5033 publications receiving 82022 citations.
Papers published on a yearly basis
Papers
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TL;DR: The results showed that the overall biomagnification of the atrazine in the different environmental systems showed that it is showing toxic effects on humans and plants, whereas degraded by the bacterial systems.
Abstract: Atrazine is the most commonly used herbicide worldwide in the agricultural system. The increased environmental concentration of the atrazine showed the toxic effects on the non-target living species. Biodegradation of the atrazine is possible with the bacterial systems. The present study investigated biodegradation potential of atrazine degrading bacteria and the impact of atrazine on environmental systems. Model of atrazine fate in ecological systems constructed using the cell designer. The used model further analyzed and simulated to know the biochemistry and physiology of the atrazine in different cellular networks. Topological analysis of the atrazine degradation confirmed the 289 nodes and 300 edges. Our results showed that the overall biomagnification of the atrazine in the different environmental systems. Atrazine is showing toxic effects on humans and plants, whereas degraded by the bacterial systems. To date, no one has analyzed the complete degradation and poisonous effects of the atrazine in the environment. Therefore, this study is useful for overall system biology based modeling and simulation analysis of atrazine in living systems. Communicated by Ramaswamy H. Sarma.
35 citations
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TL;DR: This review provides comprehensive information of potential inhibitors identified through several computational methods thus far against 3CLpro from SARS-CoV-2 and provides a better understanding of their interaction patterns and dynamic states of free and ligand-bound 3CL Pro structures.
35 citations
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TL;DR: These findings indicate that P. acidus- mediated green-synthesized AgNPs could be a potential therapeutics to treat inflammatory diseases.
35 citations
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TL;DR: The feasibility of employing bacteria as a tool to screen for EPI’s targeting ABC pumps of cancerous cells is reasoned out and the importance of efflux pump inhibitors (EPI) to mitigate drug resistance is underscore.
Abstract: Drug resistance is a serious concern in a clinical setting jeopardizing treatment for both infectious agents and cancers alike. The wide-spread emergence of multi-drug resistant (MDR) phenotypes fr...
35 citations
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TL;DR: The latest and updated information including some new techniques of immobilization related to L-asparaginase such as gelatin, Agarose, agar, and calcium alginate methods are described in detail along with response time studies and comparative data.
Abstract: The present work aims at the development of plant asparaginase-based asparagine biosensor for leukemia. It is a novel diagnostic for monitoring asparagine levels in patients suffering from acute lymphoblastic leukemia (ALL). Various immobilization strategies have been applied to improve the stability of the asparaginase. The latest and updated information including some new techniques of immobilization related to L-asparaginase such as gelatin, agarose, agar, and calcium alginate methods are described in detail along with response time studies and comparative data. Furthermore these immobilization techniques have been applied for the detection of asparagine in normal and leukemia serum samples.
35 citations
Authors
Showing all 4812 results
Name | H-index | Papers | Citations |
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Ashok Pandey | 96 | 796 | 43038 |
Klaus Becker | 79 | 320 | 27494 |
Bansi D. Malhotra | 75 | 375 | 19419 |
Ashwani Kumar | 66 | 703 | 18099 |
Sanjay K. Banerjee | 62 | 798 | 30044 |
M. Michael Gromiha | 56 | 352 | 10617 |
Swaran J.S. Flora | 55 | 267 | 11434 |
Mallappa Kumara Swamy | 54 | 864 | 14508 |
Pulok K. Mukherjee | 54 | 296 | 10873 |
Mukesh Doble | 51 | 364 | 9826 |
Jaya Narayan Sahu | 49 | 157 | 9569 |
Pradeep Das | 49 | 426 | 10118 |
Jon R. Lorsch | 48 | 117 | 7661 |
Rakesh Tuli | 47 | 165 | 7497 |
Amit K. Goyal | 47 | 157 | 5749 |