Donghua University

About: Donghua University is a education organization based out in Shanghai, China. It is known for research contribution in the topics: Fiber & Nanofiber. The organization has 21155 authors who have published 21841 publications receiving 393091 citations. The organization is also known as: Dōnghuá Dàxué & China Textile University.

High-performance flexible asymmetric supercapacitors based on 3D porous graphene/MnO2 nanorod and graphene/Ag hybrid thin-film electrodes

Abstract: We demonstrate a simple method for preparing flexible, free-standing, three-dimensional porous graphene/MnO2 nanorod and graphene/Ag hybrid thin-film electrodes using a filtration assembly process. These graphene hybrid films, which accelerate ion and electron transport by providing lower ion-transport resistances and shorter diffusion-distances, exhibit high specific capacitances and power performances, and excellent mechanical flexibility. A novel asymmetric supercapacitor (SC) has been fabricated by using a graphene/MnO2 nanorod thin film as the positive electrode and a graphene/Ag thin film as the negative electrode. These devices exhibit a maximum energy density of 50.8 W h kg−1 and present a high power density of 90.3 kW kg−1, even at an energy density of 7.53 W h kg−1. The bent hybrid nanostructured asymmetric SC is connected to spin a fan, which also proved the high power density of the fabricated asymmetric SCs. These results suggest that such asymmetric graphene/MnO2 nanorod and graphene/Ag hybrid thin-film architectures are promising for next-generation high-performance flexible supercapacitors.

Laponite nanodisks as an efficient platform for Doxorubicin delivery to cancer cells.

Abstract: We report a facile approach to using laponite (LAP) nanodisks as a platform for efficient delivery of doxorubicin (DOX) to cancer cells. In this study, DOX was encapsulated into the interlayer space of LAP through an ionic exchange process with an exceptionally high loading efficiency of 98.3 ± 0.77%. The successful DOX loading was extensively characterized via different methods. In vitro drug release study shows that the release of DOX from LAP/DOX nanodisks is pH-dependent, and DOX is released at a quicker rate at acidic pH condition (pH = 5.4) than at physiological pH condition. Importantly, cell viability assay results reveal that LAP/DOX nanodisks display a much higher therapeutic efficacy in inhibiting the growth of a model cancer cell line (human epithelial carcinoma cells, KB cells) than free DOX drug at the same DOX concentration. The enhanced antitumor efficacy is primarily due to the much more cellular uptake of the LAP/DOX nanodisks than that of free DOX, which has been confirmed by confocal laser scanning microscope and flow cytometry analysis. The high DOX payload and enhanced antitumor efficacy render LAP nanodisks as a robust carrier system for different biomedical applications.