Dubai Healthcare City

About: Dubai Healthcare City is a based out in . It is known for research contribution in the topics: Population & Visual analogue scale. The organization has 120 authors who have published 132 publications receiving 1258 citations.

Genetic loci associated with heart rate variability and their effects on cardiac disease risk

Abstract: Reduced cardiac vagal control reflected in low heart rate variability (HRV) is associated with greater risks for cardiac morbidity and mortality. In two-stage meta-analyses of genome-wide association studies for three HRV traits in up to 53,174 individuals of European ancestry, we detect 17 genome-wide significant SNPs in eight loci. HRV SNPs tag non-synonymous SNPs (in NDUFA11 and KIAA1755), expression quantitative trait loci (eQTLs) (influencing GNG11, RGS6 and NEO1), or are located in genes preferentially expressed in the sinoatrial node (GNG11, RGS6 and HCN4). Genetic risk scores account for 0.9 to 2.6% of the HRV variance. Significant genetic correlation is found for HRV with heart rate (-0.74

Effects of a yoga intervention on lipid profiles of diabetes patients with dyslipidemia

Abstract: Objective The present study was conducted to assess the effectiveness of yoga in the management of dyslipidemia in patients of type 2 diabetes mellitus.

Gaps to bridge: Misalignment between perception, reality and actions in obesity

Abstract: Aims: Despite increased recognition as a chronic disease, obesity remains greatlyunderdiagnosed and undertreated. We aimed to identify international perceptions,attitudes, behaviours and barriers to effective obesity care in people with obesity(PwO) and healthcare professionals (HCPs).Materials and methods: An online survey was conducted in 11 countries. Participantswere adults with obesity and HCPs who were primarily concerned with directpatient care.Results: A total of 14 502 PwO and 2785 HCPs completed the survey. Most PwO(68%) and HCPs (88%) agreed that obesity is a disease. However, 81% of PwOassumed complete responsibility for their own weight loss and only 44% of HCPsagreed that genetics were a barrier. There was a median of three (mean, six) yearsbetween the time PwO began struggling with excess weight or obesity and whenthey first discussed their weight with an HCP. Many PwO were concerned about theimpact of excess weight on health (46%) and were motivated to lose weight (48%).Most PwO (68%) would like their HCP to initiate a conversation about weight andonly 3% were offended by such a conversation. Among HCPs, belief that patientshave little interest in or motivation for weight management may constitute a barrierfor weight management conversations. When discussed, HCPs typically rec-ommended lifestyle changes; however, more referrals and follow-up appointmentsare required.Conclusions: Our international dataset reveals a need to increase understanding ofobesity and improve education concerning its physiological basis and clinical manage-ment. Realization that PwO are motivated to lose weight offers an opportunity forHCPs to initiate earlier weight management conversations.