Showing papers by "Dublin City University published in 1988"

Controlled comparison of a new sublingual lormetazepam formulation and i.v. diazepam in outpatient minor oral surgery

Abstract: In a randomized, double-blind, parallel groups study, 40 patients undergoing surgical removal of impacted 3rd molar teeth received either sublingual lormetazepam 2.5 mg (n = 20) in a new cellulose wafer formulation followed at 35 min by i.v. saline; or sublingual placebo followed at 35min by i.v. diazepam 10mg (Diazemuls). Rapid onset of sedation was seen after sublingual lormetazepam, while the course and duration of postoperative sedation, measured using standard psychometric tests, was similar following both treatments. Surgeons′ ratings indicated that sublingual lormetazepam was comparable to i.v. diazepam but patients′ ratings indicated greater satisfaction with and preference for i.v. diazepam. Significant anterograde amnesia was found following both treatments. Both treatments were tolerated well, with no significant cardiovascular complications. These results indicate that sublingual lormetazepam may have a role in anaesthesia as a premedicant and for conscious sedation.

Multiprocessors and multiprocessing in a distributed system

Abstract: A distributed object-oriented architecture called DUMPS with explicit primitives for exploiting parallelism that are hardware-independent is proposed. Multiprocessors do not appear as separate entities in the model, but are treated in the same way as multiple uniprocessor nodes. Synchronization and communication between processes is in terms of objective-invocations, so the model does not rely on the availability of shared memory. Continuity of the face of failure a vital characteristic of the system, is discussed. >