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Showing papers by "École Polytechnique Fédérale de Lausanne published in 1989"


Journal ArticleDOI
TL;DR: In this paper, a theory of the sensor sensitivities is developed; conditions for the waveguide parameters in order to obtain high sensitivities are derived; and it is shown that effects (1) and (2) can be distinguished by measurements of the effective index changes of both the TE0 and the TM0 modes.
Abstract: Grating couplers on planar waveguides can be used as integrated-optical sensors responding to (1) changes in the refractive index of a liquid sample covering the waveguide (differential refractometer) and (2) the adsorption and desorption, respectively, of molecules out of a gaseous or liquid sample on the waveguide (gas or chemical sensor). A theory of the sensor sensitivities is developed; conditions for the waveguide parameters in order to obtain high sensitivities are derived. It is shown that effects (1) and (2) can be distinguished by measurements of the effective index changes of both the TE0 and the TM0 modes. In the analysis both nonporous and microporous waveguiding films are considered.

630 citations


Journal ArticleDOI
02 Jun 1989-Cell
TL;DR: It is shown that in intact cells, two distinct types of ribosomal chromatin coexist in Friend cells, one that contains nucleosomes and represents the inactive copies and one that lacks a repeating structure and corresponds to the transcribed genes.

376 citations


Journal ArticleDOI
TL;DR: Wehrli and Stumm as mentioned in this paper showed that the rate of oxidation of VO2+ by oxygen is significantly enhanced by hydrolysis or adsorption to hydrous oxide surfaces and showed that coordinated OH-groups of solid surfaces are able to mediate the electron transfer from the metal ions to the O2-molecule.

364 citations


Journal ArticleDOI
TL;DR: In this paper, a new heuristic method is presented for solving the m -machine, n -job flow shop scheduling problem, which is composed of two phases: the first finds an initial sequence using an analogy with the travelling salesman problem and the second tries to improve this solution using taboo search techniques.

350 citations


Journal ArticleDOI
TL;DR: A series of low and high velocity impact tests have been conducted on a wide range of cfrp laminates to examine the initiation and development of damage under these two widely differing loading conditions as mentioned in this paper.

321 citations


Journal ArticleDOI
Abstract: A general micro/macroscopic model of solidification for 2-D or 3-D castings, valid for both dendritic and eutectic equiaxed alloys, is presented. At the macroscopic level, the heat diffusion equation is solved with an enthalpy formulation using a standard FEM implicit scheme. However, instead of using a unique relationship between temperature and enthalpy (i.e., a unique solidification path), the specific heat and latent heat contributions, whose sum equals the variation of enthalpy at a given node, are calculated using a microscopic model of solidification. This model takes into account nucleation of new grains within the undercooled melt, the kinetics of the dendrite tips or of the eutectic front, and a solute balance at the scale of the grain in the case of dendritic alloys. The coupling between macroscopic and microscopic aspects is carried out using two time-steps, one at the macroscopic level for the implicit calculation of heat flow, and the other, much finer, for the microscopic calculations of nucleation and growth. This micro/macroscopic approach has been applied to one-dimensional and axisymmetric castings of Al-7 pct Si alloys. The calculated recalescences and grain sizes are compared with values measured for one-dimensional ingots cast under well-controlled conditions. Furthermore, the influence of casting conditions on temperature field, undercooling, grain size, and microstructural spacings is shown to be predicted correctly from axisymmetric calculations with regard to the expected experimental behavior.

300 citations


Proceedings ArticleDOI
01 Jul 1989
TL;DR: The solution to the grasping problem is based on displacement commands instead of force commands used in robotics and human behavior, which allows a realistic envelope deformation of the human fingers comparable to existing methods.
Abstract: This paper addresses the problem of simulating deformations between objects and the hand of a synthetic character during a grasping process. A numerical method based on finite element theory allows us to take into account the active forces of the fingers on the object and the reactive forces of the object on the fingers. The method improves control of synthetic human behavior in a task level animation system because it provides information about the environment of a synthetic human and so can be compared to the sense of touch. Finite element theory currently used in engineering seems one of the best approaches for modeling both elastic and plastic deformation of objects, as well as shocks with or without penetration between deformable objects. We show that intrinsic properties of the method based on composition/decomposition of elements have an impact in computer animation. We also state that the use of the same method for modeling both objects and human bodies improves the modeling both objects and human bodies improves the modeling of the contacts between them. Moreover, it allows a realistic envelope deformation of the human fingers comparable to existing methods. To show what we can expect from the method, we apply it to the grasping and pressing of a ball. Our solution to the grasping problem is based on displacement commands instead of force commands used in robotics and human behavior.

262 citations


Journal ArticleDOI
TL;DR: Tabu Search is a general heuristic procedure for global optimization as mentioned in this paper, based on simple ideas it has been extremely efficient in getting almost optimal solutions for many types of difficult combinatorial optimization problems.
Abstract: Tabu Search is a general heuristic procedure for global optimization. Based on simple ideas it has been extremely efficient in getting almost optimal solutions for many types of difficult combinatorial optimization problems. The principles of Tabu Search are discribed and illustrations are given. An example of problem type where the use of Tabu Search has drastically cut down the computational effort is presented; it consists of the learning process of an associative memory represented by a neural network.

195 citations


Journal ArticleDOI
TL;DR: It is suggested that the optimal strategy in genotoxicity screening is to start with chronic exposure of 3-day-old larvae for 48 h (that is, until pupation) and only for unstable compounds and very volatile compounds and gases are acute treatments, including inhalation, recommended.
Abstract: The Drosophila wing somatic mutation and recombination test (SMART) was evaluated for its suitability in genotoxicity screening by testing 30 chemicals. Of the 2 crosses used, the mwh-flr 3 cross turned out to be more convenient than the previously used mwh-flr cross. Based on the experience gained with both acute exposures and chronic exposures of different duration, we suggest that the optimal strategy in genotoxicity screening is to start with chronic exposure of 3-day-old larvae for 48 h (that is, until pupation). Only for unstable compounds and very volatile compounds and gases are acute treatments, including inhalation, recommended. In general, a qualitative evaluation of the genotoxicity of a compound in the wing assay is possible with as few as 1–2 different exposure concentrations. A more quantitative evaluation of genotoxicity, based upon dose-response data, can often be achieved with as few as 3–4 concentrations. The results reported here were obtained in 2 different laboratories, demonstrating that the wing spot test is easily transferable to other laboratories. The experience gained indicates that the assay has now been developed to an extent that a coordinated international comparative validation study is desirable.

190 citations


Journal ArticleDOI
TL;DR: In this paper, an analytical model for coupled eutectic growth under rapid solidification condition is compared to the experimental results, which predicts a continuous decrease in spacing as the growth rate increases, which finds its analogy in single phase solidification in the limit of absolute stability.

181 citations


Journal ArticleDOI
TL;DR: In this article, it is shown that surface processes and not transport processes control the dissolution kinetics and that all the dissolution reactions are critically dependent on the type of complexes formed on the surface of the Fe (III) (hydr) oxides.

Book ChapterDOI
26 Sep 1989
TL;DR: The implementation of causal ordering proposed in this paper uses logical clocks of Mattern-Fidge and presents two advantages over the implementation in ISIS: the information added to messages to ensure causal ordering is bounded by the number of sites in the system, and no special protocol is needed to dispose of this added information when it has become useless.
Abstract: This paper presents a new algorithm to implement causal ordering Causal ordering was first proposed in the ISIS system developed at Cornell University The interest of causal ordering in a distributed system is that it is cheaper to realize than total ordering The implementation of causal ordering proposed in this paper uses logical clocks of Mattern-Fidge (which define a partial order between events in a distributed system) and presents two advantages over the implementation in ISIS: (1) the information added to messages to ensure causal ordering is bounded by the number of sites in the system, and (2) no special protocol is needed to dispose of this added information when it has become useless The implementation of ISIS presents however advantages in the case of site failures

Journal ArticleDOI
TL;DR: In this paper, the authors show that the high creep strength of tempered martensite ferritic steels results from the presence of a dislocation network of subgrain boundaries (SGBs) which is stabilized by carbides.

Journal ArticleDOI
TL;DR: The activity of the membrane-bound and the purified erythrocyte Ca2+-ATPase in the absence of calmodulin was stimulated by calpain digestion but could be further increased to maximal levels bycalmodulin (CaM) and retained by the digested ATPase, at least at short times of incubation.

Journal ArticleDOI
TL;DR: In this article, a self-energy correction to the local density approximation is derived from the GW approximation of the self energy operator, which consists of a ''scissor'' operator and additional nonrigid corrections.
Abstract: A model self-energy correction to the local-density approximation is derived from the GW approximation of the self-energy operator Excitation energies calculated in diamond, Si, Ge, GaAs, and AlAs compare favorably with those obtained with the full GW approximation Results for GaP are close to experimental data It is shown that the model consists of a ``scissor'' operator and additional nonrigid corrections


Journal ArticleDOI
TL;DR: In this paper, a particle simulation code, TDA, which models the single-pass amplification process in a free-electron-laser (FEL) is developed and tested.

Journal ArticleDOI
TL;DR: The primary structure of a region of the erythrocyte plasma membrane calcium pump which is phosphorylated by the cAMP-dependent protein kinase has been determined and the sequence is A-P-T-K-R-N-S-S(P)-P-P
Abstract: The primary structure of a region of the erythrocyte plasma membrane calcium pump which is phosphorylated by the cAMP-dependent protein kinase has been determined. The sequence is A-P-T-K-R-N-S-S(P)-P-P-P-S-P-D. The site is located between the calmodulin binding domain and the C-terminus of the ATPase. The ATPase is phosphorylated only at this site by the cAMP-dependent protein kinase, and the phosphorylation is inhibited by calmodulin. The effect of the phosphorylation is to decrease the Km for Ca2+ of the purified ATPase from about 10 microM to about 1.4 microM and to increase the Vmax of ATP hydrolysis about 2-fold.

Journal ArticleDOI
TL;DR: The role of oxalate in accelerating the reductive dissolution of hematite by ascorbate is believed to be similar to its role in promoting the non-reductive dissolution of metal oxides.

Journal ArticleDOI
TL;DR: In this paper, an ion-microprobe dating of zircon from various sediments and metasediments of the European Hercynides (Moldanubian of northeastern Bavaria and the Massif Central).

Journal ArticleDOI
TL;DR: A geochemical and geochronological study of the Alpine External Crystalline Massifs (AECM) of Aiguilles Rouges, Belledonne and Argentera was undertaken in order to constrain the geodynamic evolution of this segment of the Variscan foldbelt as discussed by the authors.

Journal ArticleDOI
TL;DR: This paper reviews the various approaches that have been taken and assesses which of them may provide routine transformation methods for cereals and what biological peculiarities of cereals may hold the key to future success.

Journal ArticleDOI
TL;DR: In this article, the authors reported the evidence for enhancement of critical current density by ∼50%, which occurs when ∼10 wt. % Ag is added to Y1Ba2Cu3O7−δ ceramics.
Abstract: We report the evidence for enhancement of critical current density Jc by ∼50%, which occurs when ∼10 wt. % Ag is added to Y1Ba2Cu3O7−δ ceramics. The maximal Jc (∼700 A/cm2 at T=77 K) appears simultaneously with maximum YBaCuO compactness in the samples. The silver fills the intergranular space (holes) without Cu substitution, and the critical temperature Tc is not reduced from the bulk value (∼91 K). Normal‐state resistivity of Ag‐YBaCuO samples is decreased by an order of magnitude, and samples exhibit improved contact resistance and resistance to water. While the critical density is improved by adding ∼10 wt. % Ag, it decreases at higher Ag concentrations.

Journal ArticleDOI
TL;DR: In this paper, the authors characterized the resistance of spruce beams with the aid of nondestructive ultrasonic measurements, which constitutes the basis of an objective concept for classification of sawn timber guaranteeing a better reliability and profitability with regard to the visual grading rules used in Western Europe.
Abstract: The resistance of spruce beams was characterized with the aid of nondestructive ultrasonic measurements. The modulus of elasticity and the modulus of rupture in flexure for beams of commercial sized section can be estimated by observing the speed of propagation of a longitudinal wave applied to the longitudinal axis of the beam. The use of simple ultrasonic equipment and two experimental transducers (in direct and dry contact) permit measurements to be performed in industry. The technique constitutes the basis of an objective concept for classification of sawn timber guaranteeing a better reliability and profitability with regard to the visual grading rules used in Western Europe.

Journal ArticleDOI
TL;DR: Skin of patients with severe generalized recessive dystrophic epidermolysis bullosa (SGRDEB) was studied by immunoelectron microscopy and immunoblotting with antibodies to type VII collagen, a major structural component of anchoring fibrils, to suggest that a genetic defect in the correct synthesis, secretion, or in the molecular assembly oftype VII collagen may underlie S GRDEB.

Journal ArticleDOI
TL;DR: The characterization of colloids from the Grimsel Test Site granitic groundwater has been carried out after concentrating the natural colloids by diaultrafiltration in situ and in the laboratory as discussed by the authors.

Journal ArticleDOI
TL;DR: In this article, the authors present an ab initio approach to piezoelectricity, which is given by the stress induced by a homogeneous electric field, treated self-consistently by linear response, thus avoiding both supercells and numerical differentiation.
Abstract: We present a novel ab initio approach to piezoelectricity. The piezoelectric tensor is given by the stress induced by a homogeneous electric field. The perturbation is treated self-consistently by linear response, thus avoiding both supercells and numerical differentiation. We calculate the piezoelectric constants of none III-V semiconductors: as a by-product we also provide the first systematic study of zone-center phonons, internal strain parameters, effective charges, and dielectric constants. Our results agree very well with experiments where available, and allow predictions where they are not.

Journal ArticleDOI
TL;DR: A 3D knee model was developed in order to evaluate the mechanical behaviour during flexion of condylar-type knee prosthesis and it is concluded that this computer program may be, within its limitations, a useful tool in the preliminary evaluation of new condylars-type knees prosthesis designs.

Journal ArticleDOI
TL;DR: In this paper, the influence of the reaction medium upon the enantioselective hydrogenation of α-ketoesters to the corresponding α-hydroxyesters has been studied, using a commercial platinum-on-alumina catalyst modified with cinchonidine.

Journal ArticleDOI
TL;DR: In this paper, a Clausius-Clapeyron-like model was proposed to describe the coupling between stress and phase transition in cobalt. But it was shown that this internal friction is a function of T / v T temperature rate, v vibration frequency, but is not proportional to T/ v.