Edinburgh Napier University

About: Edinburgh Napier University is a education organization based out in Edinburgh, United Kingdom. It is known for research contribution in the topics: Population & Health care. The organization has 2665 authors who have published 6859 publications receiving 175272 citations.

Parenting a young person with mental health problems: temporal disruption and reconstruction.

Abstract: The article explores the experiences of parents living with a young person with mental health problems. Qualitative interviews were conducted with 25 parents (18 mothers and 7 fathers) whose child had a diagnosed psychiatric condition. It is argued that the parents engaged in a form of narrative reconstruction of their dual roles as parents and carers as they tried to make sense of the illness in their lives by reconstructing their past, present and future experiences. The concept 'responsibility' was threaded through the parents' narratives and is discussed in relation to three key dimensions - moral responsibility; causal responsibility; and responsibility for self. It is argued that the moral imperative to care for their child was the dominant theme in the parents' narratives but that this was challenged by their lack of knowledge of psychiatric conditions; their interactions with healthcare professionals; their relationships with their child; and their difficulties in coping with the extended parental responsibility that arose from their caring role.

Interaction between nanoparticles and cytokine proteins: impact on protein and particle functionality.

Abstract: There is increased use of nanomaterials in many applications due to their unique properties, such as their high surface area and surface reactivity. However, the potential health effects to workers, consumers and the environment exposed to nanoparticles (NPs) is unknown. The aim of this study was to investigate whether NPs which may enter the body could adsorb proteins and whether this interaction affects both the particle and the protein function. The cytokines IL-8 and TNF-α were adsorbed significantly more by 14 nm carbon black (CB) compared with a similar dose of 260 nm CB. Uncoated 14 nm CB particles produced a significant increase in intracellular calcium [Ca2 + ]i which was greater than a similar mass dose of 260 nm CB. The 260 nm CB produced an increase in ICAM-1 expression in A549 epithelial cells at a comparable dose of 14 nm CB, and after coating with TNF-α 260 nm CB produced significantly more ICAM-1 expression compared with control cells. TNF-α bound to 14 nm CB induced a level of ICAM-1 expression that was no greater than the control level, suggesting that the TNF-α activity may be inhibited. These results suggest that NP–protein interaction results both in a decrease in protein function and particle activity in the cellular assays tested and this is currently being investigated.

Life After Mining: Hidden Unemployment and Changing Patterns of Economic Activity amongst Miners in England and Wales, 1981-1991:

Abstract: Official counts of unemployment in the coalfields have not reflected the large-scale losses of thousands of jobs from the mining industry in the 1980s and 1990s. Recent studies have suggested that there are indeed high incidences of unemployment among ex-miners and that much of the unemployment in the coalfields is `hidden', masked by the removal of miners from the official unemployment register through early retirement or being classed permanently sick. This paper examines how miners have been absorbed into the labour market over a ten-year period, between 1981 and 1991. Using data from the ONS Longitudinal Study a sample of miners are identified in 1981 and their labour market position in 1991 examined. The data are used to highlight changes in occupation, employment status and social class. In addition, regional differences in unemployment and joblessness are assessed.