Institution
Edinburgh Napier University
Education•Edinburgh, United Kingdom•
About: Edinburgh Napier University is a education organization based out in Edinburgh, United Kingdom. It is known for research contribution in the topics: Population & Health care. The organization has 2665 authors who have published 6859 publications receiving 175272 citations.
Papers published on a yearly basis
Papers
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TL;DR: There is a lack of large, high-quality published RCTs evaluating debridement per se, or comparing different methods of debridements for surgical wounds, to guide clinical decision-making.
Abstract: Background
Surgical wounds that become infected are often debrided because clinicians believe that removal of this necrotic or infected tissue will expedite wound healing. There are numerous methods available but no consensus on which one is most effective for surgical wounds.
Objectives
To determine the effect of different methods of debridement on the rate of debridement and healing of surgical wounds.
Search methods
In March 2013, for this third update, we searched the Cochrane Wounds Group Specialised Register; the Cochrane Central Register of Controlled Trials (CENTRAL) (The Cochrane Library); Ovid MEDLINE; Ovid MEDLINE (In-Process & Other Non-Indexed Citations); Ovid EMBASE; and EBSCO CINAHL.
Selection criteria
We included randomised controlled trials (RCTs) with outcomes including at least one of the following: time to complete debridement or time to complete healing.
Data collection and analysis
Two review authors independently reviewed the abstracts and titles obtained from the search, extracted data independently using a standardised extraction sheet and independently assessed methodological quality. One review author was involved in all stages of the data collection and extraction process, thus ensuring continuity.
Main results
Five RCTs (159 participants) were eligible for inclusion; all compared treatments for infected surgical wounds and reported time required to achieve a clean wound bed (complete debridement). One trial compared an enzymatic agent (streptokinase/streptodornase) with saline-soaked dressings. Four trials compared the effectiveness of dextranomer beads or paste with other products (different comparator in each trial) to achieve complete debridement. Meta-analysis was not possible due to the unique comparisons within each trial. One trial reported that dextranomer achieved a clean wound bed significantly more quickly than Eusol, and one trial comparing enzymatic debridement with saline-soaked dressings reported that the enzyme-treated wounds were cleaned more quickly. However, methodological quality was poor in these two trials.
Authors' conclusions
There is a lack of large, high-quality published RCTs evaluating debridement per se, or comparing different methods of debridement for surgical wounds, to guide clinical decision-making.
66 citations
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TL;DR: In this article, the authors analyzed over 200 technology-driven companies which have been created under the formal requirement of a business plan competition since 1996 and identified drivers for innovation and success.
Abstract: Entrepreneurship and innovation education has derived from established university curriculum and the context is set of concepts and tools used in the corporate world. The challenge of transforming a start‐up company into a business success needs different capabilities. It goes beyond the development of an idea and writing‐up a comprehensive business plan. This study analysed over 200 technology‐driven companies which have been created under the formal requirement of a business plan competition since 1996. The objective was to identify drivers for innovation and success. From the results, an agenda of entrepreneurial and innovation education was derived and is discussed.
66 citations
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TL;DR: Patterns of morphological variability in this species are largely determined by the local environmental conditions: local factors could have a within-generation selective influence on mean trait values or C. maenas may exhibit phenotypic plasticity.
66 citations
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TL;DR: The findings from this study demonstrate that the mechanism of action of cathelicidins against rhinovirus is by directly affecting the virus and it is proposed that the delivery of exogenous cathe Alicidins, or novel synthetic analogues, represent an exciting and novel therapeutic strategy for rhinOVirus infection.
66 citations
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01 Aug 2002TL;DR: The three main types of emission models, namely emission factor models, average speed models and modal models, are covered and each project is analysed regarding its characteristic parameters, including data collection technique, methodology, statistical analysis and pollutants covered.
Abstract: This article reviews the latest and relevant work on both vehicular emission models and driving cycles. The three main types of emission models, namely emission factor models, average speed models and modal models, are covered. Each project is analysed regarding its characteristic parameters, such as data collection technique, methodology, statistical analysis and pollutants covered, where appropriate. Other parameters were taken into account, such as the project objectives, results and relevance regarding the wider spectrum of the road traffic situation.
66 citations
Authors
Showing all 2727 results
Name | H-index | Papers | Citations |
---|---|---|---|
William MacNee | 123 | 472 | 58989 |
Richard J. Simpson | 113 | 850 | 59378 |
Ken Donaldson | 109 | 385 | 47072 |
John Campbell | 107 | 1150 | 56067 |
Muhammad Imran | 94 | 3053 | 51728 |
Barbara Rothen-Rutishauser | 70 | 339 | 17348 |
Vicki Stone | 69 | 204 | 25002 |
Sharon K. Parker | 68 | 238 | 21089 |
Matt Nicholl | 66 | 224 | 15208 |
John H. Adams | 66 | 354 | 16169 |
Darren J. Kelly | 65 | 252 | 13007 |
Neil B. McKeown | 65 | 281 | 19371 |
Jane K. Hill | 62 | 147 | 20733 |
Min Du | 61 | 326 | 11328 |
Xiaodong Liu | 60 | 474 | 14980 |