Edinburgh Napier University

About: Edinburgh Napier University is a education organization based out in Edinburgh, United Kingdom. It is known for research contribution in the topics: Population & Context (language use). The organization has 2665 authors who have published 6859 publications receiving 175272 citations.

Power analysis attacks on the AES-128 S-box using differential power analysis (DPA) and correlation power analysis (CPA)

Abstract: This article demonstrates two fundamental techniques of power analysis, differential power analysis (DPA) and correlation power analysis (CPA), against a modern piece of hardware which is widely av...

Novel Online Sequential Learning-Based Adaptive Routing for Edge Software-Defined Vehicular Networks

Abstract: To provide efficient networking services at the edge of Internet-of-Vehicles (IoV), Software-Defined Vehicular Network (SDVN) has been a promising technology to enable intelligent data exchange without giving additional duties to the resource constrained vehicles. Compared with conventional centralized SDVNs, hybrid SDVNs combine the centralized control of SDVNs and self-organized distributed routing of Vehicular Ad-hoc NETworks (VANETs) to mitigate the burden on the central controller caused by the frequent uplink and downlink transmissions. Although a wide variety of routing protocols have been developed, existing protocols are designed for specific scenarios without considering flexibility and adaptivity in dynamic vehicular networks. To address this problem, we propose an efficient online sequential learning-based adaptive routing scheme, namely, Penicillium reproduction-based Online Learning Adaptive Routing scheme (POLAR) for hybrid SDVNs. By utilizing the computational power of edge servers, this scheme can dynamically select a routing strategy for a specific traffic scenario by learning the pattern from network traffic. Firstly, this paper applies Geohash to divide the large geographical area into multiple grids, which facilitates the collection and processing of real-time traffic data for regional management in controller. Secondly, a new Penicillium Reproduction Algorithm (PRA) with outstanding optimization capabilities is designed to improve the learning effectiveness of Online Sequential Extreme Learning Machine (OS-ELM). Finally, POLAR is deployed in control plane to generate decision-making model (i.e., routing policy). Based on the real-time featured data, this scheme can choose the optimal routing strategy for a specific area. Extensive simulation results show that POLAR is superior to a single traditional routing protocol in terms of packet delivery ratio and latency.

Modification of the inverse association between dietary vitamin D intake and colorectal cancer risk by a FokI variant supports a chemoprotective action of Vitamin D intake mediated through VDR binding

Abstract: Vitamin D has anticarcinogenic properties and might influence colorectal cancer (CRC) risk, but the epidemiological evidence is inconsistent. Many mechanisms of action for vitamin D have been proposed, with some of them initiating via its binding to the vitamin D receptor (VDR). Using a large Scottish case-control study, we investigated (i) main associations between CRC, vitamin D and calcium dietary intake and 4 VDR single nucleotide polymorphisms (rs10735810, rs1544410, rs11568820, rs7975232) and (ii) interaction associations between the VDR variants, vitamin D and calcium intakes. Inverse and dose-dependent associations were found between CRC risk, dietary [Odds ratio (OR) = 0.77, 95% confidence intervals (CI) 0.63, 0.92, p-trend = 0.012] and total vitamin D (OR = 0.80, 95% CI 0.65, 0.98, p-trend = 0.014) intake in multivariable-adjusted logistic regression models, whereas neither calcium intake nor any of the VDR variants were associated with CRC. Additionally, we observed statistically significant interactions (case-control, case-only designs) between vitamin D and calcium intake and rs10735810 (p-interaction 0.02, 0.006, respectively). We conducted meta-analyses of cohort, case-control and serum studies that also showed an inverse association between dietary vitamin D intake and CRC (serum studies: combined OR = 0.70, 95% CI 0.56, 0.87). The evidence of interaction we report here further supports the inverse association between vitamin D mediated through binding to the VDR.