Institution
Edith Cowan University
Education•Perth, Western Australia, Australia•
About: Edith Cowan University is a education organization based out in Perth, Western Australia, Australia. It is known for research contribution in the topics: Population & Tourism. The organization has 4040 authors who have published 13529 publications receiving 339582 citations. The organization is also known as: Edith Cowan & ECU.
Topics: Population, Tourism, Isometric exercise, Higher education, Health care
Papers published on a yearly basis
Papers
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TL;DR: Evidence from animal and human trials indicates that bone responds positively to impact activities and high intensity progressive resistance training, and the optimisation of muscle strength, balance and mobility minimises the risk of falls.
208 citations
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TL;DR: By using a pyramid sampling approach combined with simulated reannealing the authors find that registration can be achieved to predetermined precision, subject to choice of interpolation and the constraint of time.
Abstract: The registration of retinal images is required to facilitate the study of the optic nerve head and the retina. The method the authors propose combines the use of mutual information as the similarity measure and simulated annealing as the search technique. It is robust toward large transformations between the images and significant changes in light intensity. By using a pyramid sampling approach combined with simulated reannealing the authors find that registration can be achieved to predetermined precision, subject to choice of interpolation and the constraint of time. The algorithm was tested on 49 pairs of stereo images and 48 pairs of temporal images with success.
207 citations
25 Jun 2007
TL;DR: In this paper, the authors argue that design-based research is feasible for doctoral students, and that candidates should be encouraged to engage in it more specifically, they describe the components of a dissertation proposal or prospectus that utilizes designbased research methods in the context of educational technology research.
Abstract: At first glance, design-based research may appear to be such a long-term and intensive approach to educational inquiry that doctoral students, most of whom expect to complete their PhD degree in 4-5 years, should not attempt to adopt this approach for their doctoral dissertations In this paper, we argue that design-based research is feasible for doctoral students, and that candidates should be encouraged to engage in it More specifically, we describe the components of a dissertation proposal or prospectus that utilizes design-based research methods in the context of educational technology research
207 citations
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TL;DR: In this paper, a spongy bone-like graphene-silicon carbide (SiC) aerogels were fabricated by the directional freeze-casting of graphene oxide (GO) coated SiC whiskers slurry and thermal reduction of GO@SiC aerogel.
206 citations
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TL;DR: It is shown that the discriminative ability of GRS in LOAD prediction is maximised when selecting a small number of SNPs, and the number of causal common SNPs for LOAD may be less than 100, suggesting LOAD is more oligogenic than polygenic.
Abstract: Genetic association studies have identified 44 common genome-wide significant risk loci for late-onset Alzheimer’s disease (LOAD). However, LOAD genetic architecture and prediction are unclear. Here we estimate the optimal P-threshold (Poptimal) of a genetic risk score (GRS) for prediction of LOAD in three independent datasets comprising 676 cases and 35,675 family history proxy cases. We show that the discriminative ability of GRS in LOAD prediction is maximised when selecting a small number of SNPs. Both simulation results and direct estimation indicate that the number of causal common SNPs for LOAD may be less than 100, suggesting LOAD is more oligogenic than polygenic. The best GRS explains approximately 75% of SNP-heritability, and individuals in the top decile of GRS have ten-fold increased odds when compared to those in the bottom decile. In addition, 14 variants are identified that contribute to both LOAD risk and age at onset of LOAD.
206 citations
Authors
Showing all 4128 results
Name | H-index | Papers | Citations |
---|---|---|---|
Paul Jackson | 141 | 1372 | 93464 |
William J. Kraemer | 123 | 755 | 54774 |
D. Allan Butterfield | 115 | 504 | 43528 |
Kerry S. Courneya | 112 | 608 | 49504 |
Robert U. Newton | 109 | 753 | 42527 |
Roger A. Barker | 101 | 620 | 39728 |
Ralph N. Martins | 95 | 630 | 35394 |
Wei Wang | 95 | 3544 | 59660 |
David W. Dunstan | 91 | 403 | 37901 |
Peter E.D. Love | 90 | 546 | 24815 |
Andrew Jones | 83 | 695 | 28290 |
Hongqi Sun | 81 | 265 | 20354 |
Leon Flicker | 79 | 465 | 22669 |
Mark A. Jenkins | 79 | 472 | 21100 |
Josep M. Gasol | 77 | 313 | 22638 |