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Institution

Erzurum Technical University

EducationErzurum, Turkey
About: Erzurum Technical University is a education organization based out in Erzurum, Turkey. It is known for research contribution in the topics: Genotoxicity & Oxidative stress. The organization has 227 authors who have published 689 publications receiving 7291 citations.


Papers
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Journal ArticleDOI
TL;DR: In the present study a series of urea and sulfamide compounds incorporating the tetralin scaffolds were synthesized and evaluated for their acetylcholinesterase (AChE), human carbonic anhydrase (CA, EC 4.2.1) isoenzyme I, and II (hCA I and hCA II) inhibitory properties.

132 citations

Journal ArticleDOI
TL;DR: A series of ureas derived from phenethylamines were synthesized and evaluated for human carbonic anhydrase (hCA) I and II, acetylcholinesterase (AChE), and butyrylcholinerase (BChE) enzyme inhibitory activities and antioxidant properties.
Abstract: A series of ureas derived from phenethylamines were synthesized and evaluated for human carbonic anhydrase (hCA) I and II, acetylcholinesterase (AChE), and butyrylcholinesterase (BChE) enzyme inhibitory activities and antioxidant properties. The ureas were synthesized from the reactions of substituted phenethylamines with N,N-dimethylcarbamoyl chloride; then, the synthesized compounds were converted to their corresponding phenolic derivatives via O-demethylation. hCA I and II were effectively inhibited by the newly synthesized compounds, with Ki values in the range of 0.307-0.432 nM for hCA I and 0.149-0.278 nM for hCA II. On the other hand, the Ki parameters of these compounds for AChE and BChE were determined in the range of 0.129-0.434 and 0.095-0.207 nM, respectively. Phenolic ureas also showed good antioxidant activities.

125 citations

Journal ArticleDOI
TL;DR: In vitro studies were shown that all of novel synthesized benzylsulfamide analogs inhibited, concentration dependently, both hCA isoenzyme activities, both of which exhibited nanomolar inhibition constants against the two isoenzymes.

107 citations

Journal ArticleDOI
TL;DR: In this paper, a novel electrochemical AFB1 immunosensor was constructed based on Ag nanocubes (AgNCs) incorporated trigonal metallic MoS2 nanosheets with 1T phase, and gold nanoparticles/porous graphene nanoribbon (AuNPs/PGNR) as an electrochemical sensor platform.
Abstract: The accurate and precisive monitoring of aflatoxin B1 (AFB1), which is one of the most hazardous mycotoxins, especially in agricultural products, is significant for human and environmental health. AFB1 generally contaminates agricultural products such as corn and feedstuff. In this paper, a novel electrochemical AFB1 immunosensor was constructed based on Ag nanocubes (AgNCs) incorporated trigonal metallic MoS2 nanosheets with 1T phase (AgNCs/1T-MoS2) as signal amplification and gold nanoparticles/porous graphene nanoribbon (AuNPs/PGNR) as an electrochemical sensor platform. First, the chronoamperometry method was implemented to provide electrodeposition of AuNPs on PGNR following chemical reduction of PGNR. Immobilization of the primer AFB1 antibody was performed via amino-gold affinity between primer antibody and AuNPs/PGNR composite. Subsequently, the conjugation of seconder antibody to AgNCs/1T-MoS2 was performed by strong π–π and electrostatic interactions. To describe the surface morphology and elemental composition of the prepared electrochemical AFB1 immunosensor, physicochemical characterization techniques such as scanning electron microscopy (SEM), transmission electron microscopy (TEM), X-ray photoelectron spectroscopy (XPS), and X-ray diffraction (XRD) were used. Furthermore, cyclic voltammetry (CV), differential pulse voltammetry (DPV), and electrochemical impedance spectroscopy (EIS) techniques were used to evaluate the immunosensor's electrochemical performance. The developed electrochemical AFB1 immunosensor offered a good sensitivity with a detection limit (LOD) of 2.00 fg mL−1. Finally, an electrochemical AFB1 immunosensor with satisfactory selectivity, stability and reusability was applied in wheat samples with high recovery.

105 citations

Journal ArticleDOI
TL;DR: In this paper, the steady state turbulent convective heat transfer and pressure drop characteristics of Al 2 O 3 -water nanofluid inside a circular tube were investigated experimentally.

103 citations


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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
20241
202313
202227
2021157
202083
201984