Showing papers by "ETH Zurich published in 2015"
TL;DR: The compelling combination of enhanced optical properties and chemical robustness makes CsPbX3 nanocrystals appealing for optoelectronic applications, particularly for blue and green spectral regions (410–530 nm), where typical metal chalcogenide-based quantum dots suffer from photodegradation.
Abstract: Metal halides perovskites, such as hybrid organic–inorganic CH3NH3PbI3, are newcomer optoelectronic materials that have attracted enormous attention as solution-deposited absorbing layers in solar cells with power conversion efficiencies reaching 20%. Herein we demonstrate a new avenue for halide perovskites by designing highly luminescent perovskite-based colloidal quantum dot materials. We have synthesized monodisperse colloidal nanocubes (4–15 nm edge lengths) of fully inorganic cesium lead halide perovskites (CsPbX3, X = Cl, Br, and I or mixed halide systems Cl/Br and Br/I) using inexpensive commercial precursors. Through compositional modulations and quantum size-effects, the bandgap energies and emission spectra are readily tunable over the entire visible spectral region of 410–700 nm. The photoluminescence of CsPbX3 nanocrystals is characterized by narrow emission line-widths of 12–42 nm, wide color gamut covering up to 140% of the NTSC color standard, high quantum yields of up to 90%, and radiativ...
6,170 citations
TL;DR: A review of the Pascal Visual Object Classes challenge from 2008-2012 and an appraisal of the aspects of the challenge that worked well, and those that could be improved in future challenges.
Abstract: The Pascal Visual Object Classes (VOC) challenge consists of two components: (i) a publicly available dataset of images together with ground truth annotation and standardised evaluation software; and (ii) an annual competition and workshop. There are five challenges: classification, detection, segmentation, action classification, and person layout. In this paper we provide a review of the challenge from 2008---2012. The paper is intended for two audiences: algorithm designers, researchers who want to see what the state of the art is, as measured by performance on the VOC datasets, along with the limitations and weak points of the current generation of algorithms; and, challenge designers, who want to see what we as organisers have learnt from the process and our recommendations for the organisation of future challenges. To analyse the performance of submitted algorithms on the VOC datasets we introduce a number of novel evaluation methods: a bootstrapping method for determining whether differences in the performance of two algorithms are significant or not; a normalised average precision so that performance can be compared across classes with different proportions of positive instances; a clustering method for visualising the performance across multiple algorithms so that the hard and easy images can be identified; and the use of a joint classifier over the submitted algorithms in order to measure their complementarity and combined performance. We also analyse the community's progress through time using the methods of Hoiem et al. (Proceedings of European Conference on Computer Vision, 2012) to identify the types of occurring errors. We conclude the paper with an appraisal of the aspects of the challenge that worked well, and those that could be improved in future challenges.
6,061 citations
Technische Universität München1, ETH Zurich2, University of Bern3, Harvard University4, National Institutes of Health5, University of Debrecen6, University Hospital Heidelberg7, McGill University8, University of Pennsylvania9, French Institute for Research in Computer Science and Automation10, University at Buffalo11, Microsoft12, University of Cambridge13, Stanford University14, University of Virginia15, Imperial College London16, Massachusetts Institute of Technology17, Columbia University18, Sabancı University19, Old Dominion University20, RMIT University21, Purdue University22, General Electric23
TL;DR: The Multimodal Brain Tumor Image Segmentation Benchmark (BRATS) as mentioned in this paper was organized in conjunction with the MICCAI 2012 and 2013 conferences, and twenty state-of-the-art tumor segmentation algorithms were applied to a set of 65 multi-contrast MR scans of low and high grade glioma patients.
Abstract: In this paper we report the set-up and results of the Multimodal Brain Tumor Image Segmentation Benchmark (BRATS) organized in conjunction with the MICCAI 2012 and 2013 conferences Twenty state-of-the-art tumor segmentation algorithms were applied to a set of 65 multi-contrast MR scans of low- and high-grade glioma patients—manually annotated by up to four raters—and to 65 comparable scans generated using tumor image simulation software Quantitative evaluations revealed considerable disagreement between the human raters in segmenting various tumor sub-regions (Dice scores in the range 74%–85%), illustrating the difficulty of this task We found that different algorithms worked best for different sub-regions (reaching performance comparable to human inter-rater variability), but that no single algorithm ranked in the top for all sub-regions simultaneously Fusing several good algorithms using a hierarchical majority vote yielded segmentations that consistently ranked above all individual algorithms, indicating remaining opportunities for further methodological improvements The BRATS image data and manual annotations continue to be publicly available through an online evaluation system as an ongoing benchmarking resource
3,699 citations
TL;DR: This work proposes the existence of a previously overlooked type of Weyl fermion that emerges at the boundary between electron and hole pockets in a new phase of matter and discovers a type-II Weyl point, which is still a protected crossing, but appears at the contact of electron and Hole pockets in type- II Weyl semimetals.
Abstract: Fermions--elementary particles such as electrons--are classified as Dirac, Majorana or Weyl. Majorana and Weyl fermions had not been observed experimentally until the recent discovery of condensed matter systems such as topological superconductors and semimetals, in which they arise as low-energy excitations. Here we propose the existence of a previously overlooked type of Weyl fermion that emerges at the boundary between electron and hole pockets in a new phase of matter. This particle was missed by Weyl because it breaks the stringent Lorentz symmetry in high-energy physics. Lorentz invariance, however, is not present in condensed matter physics, and by generalizing the Dirac equation, we find the new type of Weyl fermion. In particular, whereas Weyl semimetals--materials hosting Weyl fermions--were previously thought to have standard Weyl points with a point-like Fermi surface (which we refer to as type-I), we discover a type-II Weyl point, which is still a protected crossing, but appears at the contact of electron and hole pockets in type-II Weyl semimetals. We predict that WTe2 is an example of a topological semimetal hosting the new particle as a low-energy excitation around such a type-II Weyl point. The existence of type-II Weyl points in WTe2 means that many of its physical properties are very different to those of standard Weyl semimetals with point-like Fermi surfaces.
2,055 citations
TL;DR: This work reports fast, low-temperature, deliberately partial, or complete anion-exchange in highly luminescent semiconductor nanocrystals of cesium lead halide perovskites (CsPbX3, X = Cl, Br, I).
Abstract: Postsynthetic chemical transformations of colloidal nanocrystals, such as ion-exchange reactions, provide an avenue to compositional fine-tuning or to otherwise inaccessible materials and morphologies. While cation-exchange is facile and commonplace, anion-exchange reactions have not received substantial deployment. Here we report fast, low-temperature, deliberately partial, or complete anion-exchange in highly luminescent semiconductor nanocrystals of cesium lead halide perovskites (CsPbX3, X = Cl, Br, I). By adjusting the halide ratios in the colloidal nanocrystal solution, the bright photoluminescence can be tuned over the entire visible spectral region (410–700 nm) while maintaining high quantum yields of 20–80% and narrow emission line widths of 10–40 nm (from blue to red). Furthermore, fast internanocrystal anion-exchange is demonstrated, leading to uniform CsPb(Cl/Br)3 or CsPb(Br/I)3 compositions simply by mixing CsPbCl3, CsPbBr3, and CsPbI3 nanocrystals in appropriate ratios.
1,794 citations
TL;DR: A measurement of the Higgs boson mass is presented based on the combined data samples of the ATLAS and CMS experiments at the CERN LHC in the H→γγ and H→ZZ→4ℓ decay channels.
Abstract: A measurement of the Higgs boson mass is presented based on the combined data samples of the ATLAS and CMS experiments at the CERN LHC in the H→γγ and H→ZZ→4l decay channels. The results are obtained from a simultaneous fit to the reconstructed invariant mass peaks in the two channels and for the two experiments. The measured masses from the individual channels and the two experiments are found to be consistent among themselves. The combined measured mass of the Higgs boson is mH=125.09±0.21 (stat)±0.11 (syst) GeV.
1,567 citations
TL;DR: This work forms a rigorously probabilistic cost function that combines reprojection errors of landmarks and inertial terms and compares the performance to an implementation of a state-of-the-art stochastic cloning sliding-window filter.
Abstract: Combining visual and inertial measurements has become popular in mobile robotics, since the two sensing modalities offer complementary characteristics that make them the ideal choice for accurate visual-inertial odometry or simultaneous localization and mapping SLAM. While historically the problem has been addressed with filtering, advancements in visual estimation suggest that nonlinear optimization offers superior accuracy, while still tractable in complexity thanks to the sparsity of the underlying problem. Taking inspiration from these findings, we formulate a rigorously probabilistic cost function that combines reprojection errors of landmarks and inertial terms. The problem is kept tractable and thus ensuring real-time operation by limiting the optimization to a bounded window of keyframes through marginalization. Keyframes may be spaced in time by arbitrary intervals, while still related by linearized inertial terms. We present evaluation results on complementary datasets recorded with our custom-built stereo visual-inertial hardware that accurately synchronizes accelerometer and gyroscope measurements with imagery. A comparison of both a stereo and monocular version of our algorithm with and without online extrinsics estimation is shown with respect to ground truth. Furthermore, we compare the performance to an implementation of a state-of-the-art stochastic cloning sliding-window filter. This competitive reference implementation performs tightly coupled filtering-based visual-inertial odometry. While our approach declaredly demands more computation, we show its superior performance in terms of accuracy.
1,472 citations
TL;DR: Low-threshold amplified spontaneous emission and lasing from ∼10 nm monodisperse colloidal nanocrystals of caesium lead halide perovskites CsPbX3 are reported.
Abstract: Metal halide semiconductors with perovskite crystal structures have recently emerged as highly promising optoelectronic materials. Despite the recent surge of reports on microcrystalline, thin-film and bulk single-crystalline metal halides, very little is known about the photophysics of metal halides in the form of uniform, size-tunable nanocrystals. Here we report low-threshold amplified spontaneous emission and lasing from ∼10 nm monodisperse colloidal nanocrystals of caesium lead halide perovskites CsPbX3 (X=Cl, Br or I, or mixed Cl/Br and Br/I systems). We find that room-temperature optical amplification can be obtained in the entire visible spectral range (440–700 nm) with low pump thresholds down to 5±1 μJ cm−2 and high values of modal net gain of at least 450±30 cm−1. Two kinds of lasing modes are successfully observed: whispering-gallery-mode lasing using silica microspheres as high-finesse resonators, conformally coated with CsPbX3 nanocrystals and random lasing in films of CsPbX3 nanocrystals. Lead halide perovskite colloidal nanocrystals have promising optoelectronic properties, such as high photoluminescence quantum yields and narrow emission linewidths. Here, the authors report low-threshold amplified spontaneous emission and two kinds of lasing in nanostructured caesium lead halide perovskites.
1,305 citations
University of Nantes1, Technical University of Denmark2, British Geological Survey3, National Oceanic and Atmospheric Administration4, Cooperative Institute for Research in Environmental Sciences5, Institut de Physique du Globe de Paris6, University of Grenoble7, ETH Zurich8, University of Strasbourg9, Centre National D'Etudes Spatiales10, University of Potsdam11, University of Algiers12, Goddard Space Flight Center13, Newcastle University14, University of Maryland, Baltimore County15
TL;DR: The 12th generation of the International Geomagnetic Reference Field (IGRF) was adopted in December 2014 by the Working Group V-MOD appointed by the International Association of Geomagnetism and Aeronomy (IAGA) as discussed by the authors.
Abstract: The 12th generation of the International Geomagnetic Reference Field (IGRF) was adopted in December 2014 by the Working Group V-MOD appointed by the International Association of Geomagnetism and Aeronomy (IAGA). It updates the previous IGRF generation with a definitive main field model for epoch 2010.0, a main field model for epoch 2015.0, and a linear annual predictive secular variation model for 2015.0-2020.0. Here, we present the equations defining the IGRF model, provide the spherical harmonic coefficients, and provide maps of the magnetic declination, inclination, and total intensity for epoch 2015.0 and their predicted rates of change for 2015.0-2020.0. We also update the magnetic pole positions and discuss briefly the latest changes and possible future trends of the Earth’s magnetic field.
1,268 citations
TL;DR: In this paper, the evolution of the rest-frame UV luminosity function (LF) from to was mapped using the HST data sets from optical, near-IR, and mid-IR observations.
Abstract: The remarkable Hubble Space Telescope?(HST) data sets from the CANDELS, HUDF09, HUDF12, ERS, and BoRG/HIPPIES programs have allowed us to map the evolution of the rest-frame UV luminosity function (LF) from to . We develop new color criteria that more optimally utilize the full wavelength coverage from the optical, near-IR, and mid-IR observations over our search fields, while simultaneously minimizing the incompleteness and eliminating redshift gaps. We have identified 5859, 3001, 857, 481, 217, and 6 galaxy candidates at , , , , , and , respectively, from the ?1000 arcmin2 area covered by these data sets. This sample of >10,000 galaxy candidates at is by far the largest assembled to date with HST. The selection of 4?8 candidates over the five CANDELS fields allows us to assess the cosmic variance; the largest variations are at . Our new LF determinations at and span a 6 mag baseline and reach to ?16 AB mag. These determinations agree well with previous estimates, but the larger samples and volumes probed here result in a more reliable sampling of galaxies and allow us to reassess the form of the UV LFs. Our new LF results strengthen our earlier findings to significance for a steeper faint-end slope of the UV LF at , with ? evolving from at to at (and at ), consistent with that expected from the evolution of the halo mass function. We find less evolution in the characteristic magnitude M* from to the observed evolution in the LF is now largely represented by changes in . No evidence for a non-Schechter-like form to the z ? 4?8 LFs is found. A simple conditional LF model based on halo growth and evolution in the M/L ratio of halos provides a good representation of the observed evolution.
1,143 citations
TL;DR: It is suggested that the evidence used in many studies to assess environmental filtering is insufficient to distinguish filtering from the outcome of biotic interactions, and a simple framework for considering the role of the environment in shaping community membership is presented.
Abstract: Summary
One of the most pervasive concepts in the study of community assembly is the metaphor of the environmental filter, which refers to abiotic factors that prevent the establishment or persistence of species in a particular location. The metaphor has its origins in the study of community change during succession and in plant community dynamics, although it has gained considerable attention recently as part of a surge of interest in functional trait and phylogenetic-based approaches to the study of communities.
While the filtering metaphor has clear utility in some circumstances, it has been challenging to reconcile the environmental filtering concept with recent developments in ecological theory related to species coexistence. These advances suggest that the evidence used in many studies to assess environmental filtering is insufficient to distinguish filtering from the outcome of biotic interactions.
We re-examine the environmental filtering metaphor from the perspective of coexistence theory. In an effort to move the discussion forward, we present a simple framework for considering the role of the environment in shaping community membership, review the literature to document the evidence typically used in environmental filtering studies and highlight research challenges to address in coming years.
The current usage of the environmental filtering term in empirical studies likely overstates the role abiotic tolerances play in shaping community structure. We recommend that the term ‘environmental filtering’ only be used to refer to cases where the abiotic environment prevents establishment or persistence in the absence of biotic interactions, although only 15% of the studies in our review presented such evidence. Finally, we urge community ecologists to consider additional mechanisms aside from environmental filtering by which the abiotic environment can shape community pattern.
TL;DR: In this paper, a direct bandgap GeSn alloy, grown directly onto Si(001), was used for experimentally demonstrating lasing threshold and linewidth narrowing at low temperatures.
Abstract: Lasing is experimentally demonstrated in a direct bandgap GeSn alloy, grown directly onto Si(001). The authors observe a clear lasing threshold as well as linewidth narrowing at low temperatures.
ETH Zurich1, Delft University of Technology2, Istituto Italiano di Tecnologia3, Ghent University4, University of Chicago5, Argonne National Laboratory6, University of Pennsylvania7, Los Alamos National Laboratory8, City University of Hong Kong9, University of Grenoble10, University of Marburg11, Seoul National University12, Johannes Kepler University of Linz13, University of Erlangen-Nuremberg14
TL;DR: The state of the art in research on colloidal NCs is reviewed focusing on the most recent works published in the last 2 years, where semiconductor NCs hold unique promise for near- and mid-infrared technologies, where very few semiconductor materials are available.
Abstract: Colloidal nanocrystals (NCs, i.e., crystalline nanoparticles) have become an important class of materials with great potential for applications ranging from medicine to electronic and optoelectronic devices. Today’s strong research focus on NCs has been prompted by the tremendous progress in their synthesis. Impressively narrow size distributions of just a few percent, rational shape-engineering, compositional modulation, electronic doping, and tailored surface chemistries are now feasible for a broad range of inorganic compounds. The performance of inorganic NC-based photovoltaic and light-emitting devices has become competitive to other state-of-the-art materials. Semiconductor NCs hold unique promise for near- and mid-infrared technologies, where very few semiconductor materials are available. On a purely fundamental side, new insights into NC growth, chemical transformations, and self-organization can be gained from rapidly progressing in situ characterization and direct imaging techniques. New phenom...
TL;DR: The contribution of human-induced climate change to global heavy precipitation and hot extreme events is quantified in this paper, where the authors show that of the moderate extremes, 18% of precipitation and 75% of high-temperature events are attributable to warming.
Abstract: The contribution of human-induced climate change to global heavy precipitation and hot extreme events is quantified. The results show that of the moderate extremes, 18% of precipitation and 75% of high-temperature events are attributable to warming.
TL;DR: In this article, the authors reported the direct observation in TaAs of the long-sought-after Weyl nodes by performing bulk-sensitive soft X-ray angle-resolved photoemission spectroscopy measurements.
Abstract: Experiments show that TaAs is a three-dimensional topological Weyl semimetal. In 1929, H. Weyl proposed that the massless solution of the Dirac equation represents a pair of a new type of particles, the so-called Weyl fermions1. However, their existence in particle physics remains elusive after more than eight decades. Recently, significant advances in both topological insulators and topological semimetals have provided an alternative way to realize Weyl fermions in condensed matter, as an emergent phenomenon: when two non-degenerate bands in the three-dimensional momentum space cross in the vicinity of the Fermi energy (called Weyl nodes), the low-energy excitations behave exactly as Weyl fermions. Here we report the direct observation in TaAs of the long-sought-after Weyl nodes by performing bulk-sensitive soft X-ray angle-resolved photoemission spectroscopy measurements. The projected locations at the nodes on the (001) surface match well to the Fermi arcs, providing undisputable experimental evidence for the existence of Weyl fermionic quasiparticles in TaAs.
TL;DR: In this paper, a topological insulator is characterized by a dichotomy between the interior and the edge of a finite system: the bulk has an energy gap, and the edges sustain excitations traversing this gap.
Abstract: A topological insulator, as originally proposed for electrons governed by quantum mechanics, is characterized by a dichotomy between the interior and the edge of a finite system: The bulk has an energy gap, and the edges sustain excitations traversing this gap. However, it has remained an open question whether the same physics can be observed for systems obeying Newton’s equations of motion. We conducted experiments to characterize the collective behavior of mechanical oscillators exhibiting the phenomenology of the quantum spin Hall effect. The phononic edge modes are shown to be helical, and we demonstrate their topological protection via the stability of the edge states against imperfections. Our results may enable the design of topological acoustic metamaterials that can capitalize on the stability of the surface phonons as reliable wave guides.
TL;DR: This work reviews the state-of-the-art techniques for controlling portable active lower limb prosthetic and orthotic P/O devices in the context of locomotive activities of daily living (ADL), and considers how these can be interfaced with the user’s sensory-motor control system.
Abstract: Technological advancements have led to the development of numerous wearable robotic devices for the physical assistance and restoration of human locomotion. While many challenges remain with respect to the mechanical design of such devices, it is at least equally challenging and important to develop strategies to control them in concert with the intentions of the user. This work reviews the state-of-the-art techniques for controlling portable active lower limb prosthetic and orthotic (P/O) devices in the context of locomotive activities of daily living (ADL), and considers how these can be interfaced with the user’s sensory-motor control system. This review underscores the practical challenges and opportunities associated with P/O control, which can be used to accelerate future developments in this field. Furthermore, this work provides a classification scheme for the comparison of the various control strategies. As a novel contribution, a general framework for the control of portable gait-assistance devices is proposed. This framework accounts for the physical and informatic interactions between the controller, the user, the environment, and the mechanical device itself. Such a treatment of P/Os – not as independent devices, but as actors within an ecosystem – is suggested to be necessary to structure the next generation of intelligent and multifunctional controllers. Each element of the proposed framework is discussed with respect to the role that it plays in the assistance of locomotion, along with how its states can be sensed as inputs to the controller. The reviewed controllers are shown to fit within different levels of a hierarchical scheme, which loosely resembles the structure and functionality of the nominal human central nervous system (CNS). Active and passive safety mechanisms are considered to be central aspects underlying all of P/O design and control, and are shown to be critical for regulatory approval of such devices for real-world use. The works discussed herein provide evidence that, while we are getting ever closer, significant challenges still exist for the development of controllers for portable powered P/O devices that can seamlessly integrate with the user’s neuromusculoskeletal system and are practical for use in locomotive ADL.
TL;DR: It is shown that the isolates form assemblies resembling natural microbiota on their cognate host organs, but are also capable of ectopic leaf or root colonization, which raises the possibility of reciprocal relocation between root and leaf microbiota members.
Abstract: Roots and leaves of healthy plants host taxonomically structured bacterial assemblies, and members of these communities contribute to plant growth and health. We established Arabidopsis leaf- and root-derived microbiota culture collections representing the majority of bacterial species that are reproducibly detectable by culture-independent community sequencing. We found an extensive taxonomic overlap between the leaf and root microbiota. Genome drafts of 400 isolates revealed a large overlap of genome-encoded functional capabilities between leaf- and root-derived bacteria with few significant differences at the level of individual functional categories. Using defined bacterial communities and a gnotobiotic Arabidopsis plant system we show that the isolates form assemblies resembling natural microbiota on their cognate host organs, but are also capable of ectopic leaf or root colonization. While this raises the possibility of reciprocal relocation between root and leaf microbiota members, genome information and recolonization experiments also provide evidence for microbiota specialization to their respective niche.
National Center for Atmospheric Research1, University of Graz2, Lawrence Berkeley National Laboratory3, Centre national de la recherche scientifique4, ETH Zurich5, University of Bonn6, University of Giessen7, University of Trier8, Katholieke Universiteit Leuven9, Pacific Northwest National Laboratory10
TL;DR: This study aims to provide a common basis for CPM climate simulations by giving a holistic review of the topic, and presents the consolidated outcome of studies that addressed the added value of CPMClimate simulations compared to LSMs.
Abstract: Regional climate modeling using convection-permitting models (CPMs; horizontal grid spacing 10 km). CPMs no longer rely on convection parameterization schemes, which had been identified as a major source of errors and uncertainties in LSMs. Moreover, CPMs allow for a more accurate representation of surface and orography fields. The drawback of CPMs is the high demand on computational resources. For this reason, first CPM climate simulations only appeared a decade ago. In this study, we aim to provide a common basis for CPM climate simulations by giving a holistic review of the topic. The most important components in CPMs such as physical parameterizations and dynamical formulations are discussed critically. An overview of weaknesses and an outlook on required future developments is provided. Most importantly, this review presents the consolidated outcome of studies that addressed the added value of CPM climate simulations compared to LSMs. Improvements are evident mostly for climate statistics related to deep convection, mountainous regions, or extreme events. The climate change signals of CPM simulations suggest an increase in flash floods, changes in hail storm characteristics, and reductions in the snowpack over mountains. In conclusion, CPMs are a very promising tool for future climate research. However, coordinated modeling programs are crucially needed to advance parameterizations of unresolved physics and to assess the full potential of CPMs.
TL;DR: Here it is demonstrated a possibility to use such inexpensive semiconductors for sensitive detection of X-ray photons by direct photon-to-current conversion and a compelling combination of fast photoresponse and a high absorption cross-section for X-rays, owing to the heavy Pb and I atoms.
Abstract: The evolution of real-time medical diagnostic tools such as angiography and computer tomography from radiography based on photographic plates was enabled by the development of integrated solid-state X-ray photon detectors, based on conventional solid-state semiconductors. Recently, for optoelectronic devices operating in the visible and near infrared spectral regions, solution-processed organic and inorganic semiconductors have also attracted immense attention. Here we demonstrate a possibility to use such inexpensive semiconductors for sensitive detection of X-ray photons by direct photon-to-current conversion. In particular, methylammonium lead iodide perovskite (CH3NH3PbI3) offers a compelling combination of fast photoresponse and a high absorption cross-section for X-rays, owing to the heavy Pb and I atoms. Solution processed photodiodes as well as photoconductors are presented, exhibiting high values of X-ray sensitivity (up to 25 µC mGyair-1 cm-3) and responsivity (1.9×104 carriers/photon), which are commensurate with those obtained by the current solid-state technology.
TL;DR: An overview of the current knowledge on mineral-organic associations can be found in this article, where the authors identify key questions and future research needs, as well as a survey of the existing research work.
Abstract: Minerals and organic matter (OM) may form intricate associations via myriad interactions. In soils, the associations of OM with mineral surfaces are mainly investigated because of their role in determining the long-term retention of OM. OM “must decay in order to release the energy and nutrients that drive live processes all over the planet” ( Janzen, 2006 ). Thus, the processes and mechanisms that retain OM in soil are a central concern to very different branches of environmental research. An agronomist may want to synchronize periods of high nutrient and energy release with the growth stages of a crop. An environmental chemist may wish to either immobilize an organic soil contaminant or enhance its decomposition into less harmful metabolites, while climate scientists need to understand the processes that mediate the production of potent greenhouse gases from decomposing OM. Associations of OM with pedogenic minerals (henceforth termed mineral–organic associations (MOAs)) are known to be key controls in these and many other processes. Here we strive to present an overview of the current knowledge on MOAs and identify key questions and future research needs.
TL;DR: A full appreciation of folate's history as a public health issue, its biology, and an overview of available biomarkers and their interpretation across a range of clinical and population-based uses are provided.
Abstract: The Biomarkers of Nutrition for Development (BOND) project is designed to provide evidence-based advice to anyone with an interest in the role of nutrition in health. Specifically, the BOND program provides state-of-the-art information and service with regard to selection, use, and interpretation of biomarkers of nutrient exposure, status, function, and effect. To accomplish this objective, expert panels are recruited to evaluate the literature and to draft comprehensive reports on the current state of the art with regard to specific nutrient biology and available biomarkers for assessing nutrients in body tissues at the individual and population level. Phase I of the BOND project includes the evaluation of biomarkers for 6 nutrients: iodine, iron, zinc, folate, vitamin A, and vitamin B-12. This review represents the second in the series of reviews and covers all relevant aspects of folate biology and biomarkers. The article is organized to provide the reader with a full appreciation of folate's history as a public health issue, its biology, and an overview of available biomarkers (serum folate, RBC folate, and plasma homocysteine concentrations) and their interpretation across a range of clinical and population-based uses. The article also includes a list of priority research needs for advancing the area of folate biomarkers related to nutritional health status and development.
TL;DR: In this paper, the shape and elasticity of dura mater, the protective membrane of the brain and spinal cord, was designed and fabricated for implantable neuroprostheses, which embeds interconnects, electrodes and chemotrodes that sustain millions of mechanical stretch cycles, electrical stimulation pulses, and chemical injections.
Abstract: The mechanical mismatch between soft neural tissues and stiff neural implants hinders the long-term performance of implantable neuroprostheses. Here, we designed and fabricated soft neural implants with the shape and elasticity of dura mater, the protective membrane of the brain and spinal cord. The electronic dura mater, which we call e-dura, embeds interconnects, electrodes, and chemotrodes that sustain millions of mechanical stretch cycles, electrical stimulation pulses, and chemical injections. These integrated modalities enable multiple neuroprosthetic applications. The soft implants extracted cortical states in freely behaving animals for brain-machine interface and delivered electrochemical spinal neuromodulation that restored locomotion after paralyzing spinal cord injury.
01 Nov 2015
TL;DR: In this article, the authors examined the growth of science and identified three essential growth phases in the development of science, which each led to growth rates tripling in comparison with the previous phase: from less than 1% up to the middle of the 18th century, to 2 to 3% to the period between the two world wars, and 8 to 9% to 2010.
Abstract: Many studies (in information science) have looked at the growth of science. In this study, we reexamine the question of the growth of science. To do this we (a) use current data up to publication year 2012 and (b) analyze the data across all disciplines and also separately for the natural sciences and for the medical and health sciences. Furthermore, the data were analyzed with an advanced statistical technique—segmented regression analysis—which can identify specific segments with similar growth rates in the history of science. The study is based on two different sets of bibliometric data: (a) the number of publications held as source items in the Web of Science (WoS, Thomson Reuters) per publication year and (b) the number of cited references in the publications of the source items per cited reference year. We looked at the rate at which science has grown since the mid-1600s. In our analysis of cited references we identified three essential growth phases in the development of science, which each led to growth rates tripling in comparison with the previous phase: from less than 1% up to the middle of the 18th century, to 2 to 3% up to the period between the two world wars, and 8 to 9% to 2010.
TL;DR: In this article, simple rules collected from the surface-science literature that allow high-quality plasmonic films of aluminum, copper, gold, and silver to be easily deposited with commonly available equipment (a thermal evaporator).
Abstract: High-quality materials are critical for advances in plasmonics, especially as researchers now investigate quantum effects at the limit of single surface plasmons or exploit ultraviolet- or CMOS-compatible metals such as aluminum or copper. Unfortunately, due to inexperience with deposition methods, many plasmonics researchers deposit metals under the wrong conditions, severely limiting performance unnecessarily. This is then compounded as others follow their published procedures. In this perspective, we describe simple rules collected from the surface-science literature that allow high-quality plasmonic films of aluminum, copper, gold, and silver to be easily deposited with commonly available equipment (a thermal evaporator). Recipes are also provided so that films with optimal optical properties can be routinely obtained.
TL;DR: A new analysis shows that global warming could be limited to 1.5 °C by 2100, but that the window for achieving this is small and rapidly closing as mentioned in this paper, but this analysis does not consider the effects of human activities.
Abstract: A new analysis shows that global warming could be limited to 1.5 °C by 2100, but that the window for achieving this is small and rapidly closing.
TL;DR: It is shown that HRM outperformed shotgun proteomics both in the number of consistently identified peptides across multiple measurements and quantification of differentially abundant proteins, implying that DIA should be the preferred method for quantitative protein profiling.
University of California, San Diego1, Harvard University2, ETH Zurich3, Macquarie University4, Max Planck Society5, Albert Einstein College of Medicine6, Johns Hopkins University7, University of Georgia8, Osaka University9, Discovery Institute10, University of California, Santa Barbara11, Stanford University12, University of California, Davis13, Utrecht University14, University of Giessen15, University of Grenoble16, National Institutes of Health17, Scripps Research Institute18, Kyoto University19, Soka University of America20, Imperial College London21, National Institute of Advanced Industrial Science and Technology22, Washington University in St. Louis23
TL;DR: Author(s): Varki, Ajit; Cummings, Richard D; Aebi, Markus; Packer, Nicole H; Seeberger, Peter H; Esko, Jeffrey D; Stanley, Pamela; Hart, Gerald; Darvill, Alan; Kinoshita, Taroh; Prestegard, James J; Schnaar, Ronald L; Freeze, Hudson H; Marth, Jamey D; Bertozzi, Carolyn R.
Abstract: Author(s): Varki, Ajit; Cummings, Richard D; Aebi, Markus; Packer, Nicole H; Seeberger, Peter H; Esko, Jeffrey D; Stanley, Pamela; Hart, Gerald; Darvill, Alan; Kinoshita, Taroh; Prestegard, James J; Schnaar, Ronald L; Freeze, Hudson H; Marth, Jamey D; Bertozzi, Carolyn R; Etzler, Marilynn E; Frank, Martin; Vliegenthart, Johannes Fg; Lutteke, Thomas; Perez, Serge; Bolton, Evan; Rudd, Pauline; Paulson, James; Kanehisa, Minoru; Toukach, Philip; Aoki-Kinoshita, Kiyoko F; Dell, Anne; Narimatsu, Hisashi; York, William; Taniguchi, Naoyuki; Kornfeld, Stuart
TL;DR: The catalyst was applied for three-phase hydrogenations of alkynes and nitroarenes in a continuous-flow reactor, showing its high activity and product selectivity in comparison with benchmark catalysts based on nanoparticles.
Abstract: We report the preparation and hydrogenation performance of a single-site palladium catalyst that was obtained by the anchoring of Pd atoms into the cavities of mesoporous polymeric graphitic carbon nitride. The characterization of the material confirmed the atomic dispersion of the palladium phase throughout the sample. The catalyst was applied for three-phase hydrogenations of alkynes and nitroarenes in a continuous-flow reactor, showing its high activity and product selectivity in comparison with benchmark catalysts based on nanoparticles. Density functional theory calculations provided fundamental insights into the material structure and attributed the high catalyst activity and selectivity to the facile hydrogen activation and hydrocarbon adsorption on atomically dispersed Pd sites.
TL;DR: In this article, a zero-dimensional photonic quantum emitters can be realized using defects in the two-dimensional dichalcogenides, which can be used to construct a two dimensional quantum emitter.
Abstract: Zero-dimensional photonic quantum emitters can be realized using defects in the two-dimensional dichalcogenides.