Institution
Far Eastern Federal University
Education•Vladivostok, Russia•
About: Far Eastern Federal University is a education organization based out in Vladivostok, Russia. It is known for research contribution in the topics: Population & Plasma electrolytic oxidation. The organization has 3733 authors who have published 5357 publications receiving 38746 citations. The organization is also known as: FEFU & Dalnevostochny federalny universitet.
Papers published on a yearly basis
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Daniel J. Klionsky1, Amal Kamal Abdel-Aziz2, Sara Abdelfatah3, Mahmoud Abdellatif4 +2980 more•Institutions (777)
TL;DR: In this article, the authors present a set of guidelines for investigators to select and interpret methods to examine autophagy and related processes, and for reviewers to provide realistic and reasonable critiques of reports that are focused on these processes.
Abstract: In 2008, we published the first set of guidelines for standardizing research in autophagy. Since then, this topic has received increasing attention, and many scientists have entered the field. Our knowledge base and relevant new technologies have also been expanding. Thus, it is important to formulate on a regular basis updated guidelines for monitoring autophagy in different organisms. Despite numerous reviews, there continues to be confusion regarding acceptable methods to evaluate autophagy, especially in multicellular eukaryotes. Here, we present a set of guidelines for investigators to select and interpret methods to examine autophagy and related processes, and for reviewers to provide realistic and reasonable critiques of reports that are focused on these processes. These guidelines are not meant to be a dogmatic set of rules, because the appropriateness of any assay largely depends on the question being asked and the system being used. Moreover, no individual assay is perfect for every situation, calling for the use of multiple techniques to properly monitor autophagy in each experimental setting. Finally, several core components of the autophagy machinery have been implicated in distinct autophagic processes (canonical and noncanonical autophagy), implying that genetic approaches to block autophagy should rely on targeting two or more autophagy-related genes that ideally participate in distinct steps of the pathway. Along similar lines, because multiple proteins involved in autophagy also regulate other cellular pathways including apoptosis, not all of them can be used as a specific marker for bona fide autophagic responses. Here, we critically discuss current methods of assessing autophagy and the information they can, or cannot, provide. Our ultimate goal is to encourage intellectual and technical innovation in the field.
1,129 citations
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TL;DR: In this paper, the authors used nanoscale pump-probe imaging to reveal the real-time dynamics of skyrmions driven by current-induced spin-orbit torques.
Abstract: Magnetic skyrmions are promising candidates for future spintronic applications such as skyrmion racetrack memories and logic devices. They exhibit exotic and complex dynamics governed by topology and are less influenced by defects, such as edge roughness, than conventionally used domain walls. In particular, their non-zero topological charge leads to a predicted ‘skyrmion Hall effect’, in which current-driven skyrmions acquire a transverse velocity component analogous to charged particles in the conventional Hall effect. Here, we use nanoscale pump–probe imaging to reveal the real-time dynamics of skyrmions driven by current-induced spin–orbit torques. We find that skyrmions move at a well-defined angle ΘSkH that can exceed 30° with respect to the current flow, but in contrast to conventional theoretical expectations, ΘSkH increases linearly with velocity up to at least 100 ms−1. We qualitatively explain our observation based on internal mode excitations in combination with a field-like spin–orbit torque, showing that one must go beyond the usual rigid skyrmion description to understand the dynamics. Experiments show that when driven by electric currents, magnetic skyrmions experience transverse motion due to their topological charge — similar to the conventional Hall effect experienced by charged particles in a perpendicular magnetic field.
702 citations
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TL;DR: It is found that the composite nature of antiferromagnetic Skyrmions gives rise to different dynamical behavior due to both an applied current and temperature effects.
Abstract: Skyrmions are topologically protected entities in magnetic materials which have the potential to be used in spintronics for information storage and processing. However, Skyrmions in ferromagnets have some intrinsic difficulties which must be overcome to use them for spintronic applications, such as the inability to move straight along current. We show that Skyrmions can also be stabilized and manipulated in antiferromagnetic materials. An antiferromagnetic Skyrmion is a compound topological object with a similar but of opposite sign spin texture on each sublattice, which, e.g., results in a complete cancellation of the Magnus force. We find that the composite nature of antiferromagnetic Skyrmions gives rise to different dynamical behavior due to both an applied current and temperature effects.
476 citations
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Technische Universität München1, Novosibirsk State University2, GSI Helmholtz Centre for Heavy Ion Research3, University of Kentucky4, Fermilab5, Washington University in St. Louis6, University of Graz7, University of Vienna8, University of Maryland, College Park9, Max Planck Society10, Vienna University of Technology11, Thomas Jefferson National Accelerator Facility12, Hampton University13, University of Bonn14, University of Washington15, Complutense University of Madrid16, University of Mainz17, Moscow Institute of Physics and Technology18, University of Groningen19, University of Paris-Sud20, Indiana University21, Lawrence Livermore National Laboratory22, University of California, Davis23, University of Helsinki24, University of Virginia25, Istituto Nazionale di Fisica Nucleare26, Forschungszentrum Jülich27, University of Bern28, Warsaw University of Technology29, CERN30, Kent State University31, Utrecht University32, National Research Nuclear University MEPhI33, Lawrence Berkeley National Laboratory34, University of Valencia35, University of Granada36, Stony Brook University37, Brookhaven National Laboratory38, University of Naples Federico II39, University of Santiago de Compostela40, Ruhr University Bochum41, Far Eastern Federal University42
TL;DR: In this paper, the progress, current status, and open challenges of QCD-driven physics, in theory and in experiment, are highlighted, highlighting how the strong interaction is intimately connected to a broad sweep of physical problems, in settings ranging from astrophysics and cosmology to strongly coupled, complex systems in particle and condensed-matter physics, as well as searches for physics beyond the Standard Model.
Abstract: We highlight the progress, current status, and open challenges of QCD-driven physics, in theory and in experiment. We discuss how the strong interaction is intimately connected to a broad sweep of physical problems, in settings ranging from astrophysics and cosmology to strongly coupled, complex systems in particle and condensed-matter physics, as well as to searches for physics beyond the Standard Model. We also discuss how success in describing the strong interaction impacts other fields, and, in turn, how such subjects can impact studies of the strong interaction. In the course of the work we offer a perspective on the many research streams which flow into and out of QCD, as well as a vision for future developments.
433 citations
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TL;DR: In in vivo experiments, mice bearing MCF-7 and CT-26 tumors exhibited a significant reduction in tumor volume in the quercetin-treated group as compared to the control group (P<0.001).
Abstract: The present study focused on the elucidation of the putative anticancer potential of quercetin. The anticancer activity of quercetin at 10, 20, 40, 80 and 120 µM was assessed in vitro by MMT assay in 9 tumor cell lines (colon carcinoma CT‑26 cells, prostate adenocarcinoma LNCaP cells, human prostate PC3 cells, pheocromocytoma PC12 cells, estrogen receptor‑positive breast cancer MCF‑7 cells, acute lymphoblastic leukemia MOLT‑4 T‑cells, human myeloma U266B1 cells, human lymphoid Raji cells and ovarian cancer CHO cells). Quercetin was found to induce the apoptosis of all the tested cancer cell lines at the utilized concentrations. Moreover, quercetin significantly induced the apoptosis of the CT‑26, LNCaP, MOLT‑4 and Raji cell lines, as compared to control group (P<0.001), as demonstrated by Annexin V/PI staining. In in vivo experiments, mice bearing MCF‑7 and CT‑26 tumors exhibited a significant reduction in tumor volume in the quercetin‑treated group as compared to the control group (P<0.001). Taken together, quercetin, a naturally occurring compound, exhibits anticancer properties both in vivo and in vitro.
329 citations
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Showing all 3800 results
Name | H-index | Papers | Citations |
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A. M. Sergeev | 93 | 338 | 57652 |
Aristidis Tsatsakis | 63 | 603 | 18636 |
Teruo Ono | 56 | 480 | 15347 |
Valery V. Mikhailov | 46 | 168 | 5729 |
Valentin I. Zakharov | 40 | 153 | 14288 |
Kaoru Maruta | 40 | 152 | 5808 |
Karl Landsteiner | 37 | 96 | 5395 |
Sergei A. Kulinich | 36 | 129 | 6202 |
Natalia V. Zhukova | 36 | 112 | 3516 |
Dale G. Miquelle | 35 | 89 | 3921 |
Antti J. Niemi | 34 | 179 | 5565 |
Olga I. Nedashkovskaya | 34 | 115 | 3463 |
Valentin A. Stonik | 33 | 281 | 4074 |
Sergey I. Kudryashov | 32 | 371 | 4297 |
Aristides M. Tsatsakis | 32 | 148 | 3491 |