Institution
Federal University of São Carlos
Education•São Carlos, Brazil•
About: Federal University of São Carlos is a education organization based out in São Carlos, Brazil. It is known for research contribution in the topics: Population & Microstructure. The organization has 16471 authors who have published 34057 publications receiving 456654 citations. The organization is also known as: UFSCar & Federal University of São Carlos.
Topics: Population, Microstructure, Context (language use), Catalysis, Alloy
Papers published on a yearly basis
Papers
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TL;DR: In this article, the authors evaluated if anthropogenic alterations at distinct spatial scales (estimated by land use, riparian zone composition, and riparian forest structure) influenced stream water quality according to chemical and biological indicators in a tropical rural landscape.
102 citations
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TL;DR: In this article, a high-entropy alloy is designed for room temperature hydrogen storage based on three criteria: total valence electron concentration (VEC) of 6.4, single-phase thermodynamic stability and AB2H3 hydride formation.
102 citations
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TL;DR: The ZnWO4 nanocrystals obtained at 160 °C exhibited excellent photodegradation of Rhodamine under ultraviolet light irradiation, which was found to be related to the surface energy and the types of clusters formed on the surface of the catalyst.
Abstract: The present joint experimental and theoretical work provides in-depth understanding on the morphology and structural, electronic, and optical properties of ZnWO4 nanocrystals. Monoclinic ZnWO4 nanocrystals were prepared at three different temperatures (140, 150, and 160 °C) by a microwave hydrothermal method. Then, the samples were investigated by X-ray diffraction with Rietveld refinement analysis, field-emission scanning electron microscopy, transmission electronic microscopy, micro-Raman and Fourier transform infrared spectroscopy, ultraviolet-visible spectroscopy, and photoluminescence measurements. First-principles theoretical calculations within the framework of density functional theory were employed to provide information at the atomic level. The band structure diagram, density of states, Raman and infrared spectra were calculated to understand the effect of structural order-disorder on the properties of ZnWO4. The effects of the synthesis temperature on the above properties were rationalized. The band structure revealed direct allowed transitions between the VB and CB and the experimental results in the ultraviolet-visible region were consistent with the theoretical results. Moreover, the surface calculations allowed the association of the surface energy stabilization with the temperature used in the synthesis of the ZnWO4 nanocrystals. The photoluminescence properties of the ZnWO4 nanocrystals prepared at 140, 150, and 160 °C were attributed to oxygen vacancies in the [WO6] and [ZnO6] clusters, causing a red shift of the spectra. The ZnWO4 nanocrystals obtained at 160 °C exhibited excellent photodegradation of Rhodamine under ultraviolet light irradiation, which was found to be related to the surface energy and the types of clusters formed on the surface of the catalyst.
102 citations
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TL;DR: The prevalence of Gram-negative species in the gut and the increased plasma IL-6 in patients could be linked to low-grade inflammation and insulin resistance, and the detection of inflammatory markers could be used as diabetes predictive markers in overweight, obese and in genetically predisposed individuals to develop T2D.
Abstract: Intestinal dysbiosis and metabolic endotoxemia has been associated with metabolic disorders, such as obesity, insulin resistance and type 2 diabetes (T2D). The main goal of the present study was to evaluate the intestinal dysbiosis in Brazilian T2D patients and correlate these data with inflammatory cytokines and lipopolysaccharides (LPS) plasma concentrations. This study was approved by the Ethics Committees from Barretos Cancer Hospital and all individuals signed the informed consent form. Stool samples were required for DNA extraction, and the V3/V4 regions of bacterial 16S were sequenced using an Illumina platform. Peripheral blood were used to quantify inflammatory cytokines and plasma LPS concentrations, by CBA flex and ELISA, respectively. Statistical analyses were performed using Mann-Whitney and Spearman’s tests. Analysis of variance, diversity indexes and analysis of alpha and beta-diversity were conducted using an annotated OTU table. This study included 20 patients and 22 controls. We observed significant differences (P<0.01) in the microbiota composition (beta-diversity) between patients and controls, suggesting intestinal dysbiosis in Brazilian T2D patients. The prevalent species found in patients’ feces were the gram-negatives Prevotella copri, Bacteroides vulgatus, Bacteroides rodentium, and Bacteroides xylanisolvens. The proinflammatory interleukin-6 (IL-6) was significantly increased (P<0.05) in patients’ plasma and LPS levels were decreased. We find correlations between the proinflammatory interferon-gamma (IFN-γ) with gram-negatives Bacteroides and Prevotella species, and a positive correlation between the LPS levels and Prevotella copri reads. The Prevotella copri and Bacteroides vulgatus species were associated with insulin resistance in previous studies. In this study, we suggested that the prevalence of gram-negative species in the gut and the increased plasma IL-6 in patients could be linked to low-grade inflammation and insulin resistance. In conclusion, the Prevotella copri and Bacteroides vulgatus species could represent an intestinal microbiota signature, associated with T2D development. Furthermore, the identification of these gram-negative bacteria, and the detection of inflammatory markers, such as increased IL-6, could be used as diabetes predictive markers in overweight, obese and in genetically predisposed individuals to develop T2D.
102 citations
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TL;DR: In vitro experiments showed significant differences in the release rate of cisplatin between three different porosities, suggesting that the material is likely to make it useful as an implantable drug delivery system.
102 citations
Authors
Showing all 16693 results
Name | H-index | Papers | Citations |
---|---|---|---|
Akihisa Inoue | 126 | 2652 | 93980 |
Michael R. Hamblin | 117 | 899 | 59533 |
Daniel P. Costa | 89 | 531 | 26309 |
Elson Longo | 86 | 1454 | 40494 |
Ross Arena | 81 | 671 | 39949 |
Tom M. Mitchell | 76 | 315 | 41956 |
José Arana Varela | 76 | 748 | 23005 |
Luiz H. C. Mattoso | 66 | 455 | 17432 |
Steve F. Perry | 66 | 294 | 13842 |
Edson R. Leite | 63 | 535 | 15303 |
Juan Andrés | 60 | 493 | 13499 |
Edward R. T. Tiekink | 60 | 1967 | 21052 |
Alex A. Freitas | 60 | 345 | 14789 |
Mary F. Mahon | 59 | 539 | 14258 |
Osvaldo N. Oliveira | 59 | 614 | 16369 |