Institution
Flinders University
Education•Adelaide, South Australia, Australia•
About: Flinders University is a education organization based out in Adelaide, South Australia, Australia. It is known for research contribution in the topics: Population & Health care. The organization has 12033 authors who have published 32831 publications receiving 973172 citations. The organization is also known as: Flinders University of South Australia.
Topics: Population, Health care, Poison control, Palliative care, Mental health
Papers published on a yearly basis
Papers
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TL;DR: In this paper, the authors investigate the effects of lobbying on the cumulative level of resource conversion and examine how trade policy influences the distortions created by political corruption in tropical deforestation through lobbying.
162 citations
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TL;DR: In this article, a qualitative study extends literature on research commercialization by examining the dynamic nature of university-industry linkages (UIL), and 30 interviews conducted in Australia and Germany/the Netherlands provide evidence of the different phases through which UILs evolve and respective measures of success.
Abstract: This qualitative study extends literature on research commercialization by examining the dynamic nature of university-industry linkages (UIL). Thirty in-depth interviews conducted in Australia and Germany/the Netherlands provide evidence of the different phases through which UILs evolve and respective measures of success. Communication, understanding, trust, and people are universal drivers, yet managers must consider the variations in the nature of these factors to ensure successful UILs. This study equips managers involved in technology transfer, innovation, and commercialization with critical insights into developing effective relationships. The proposed conceptual framework also uncovers notable theoretical and managerial implications and offers some key research directions.
162 citations
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TL;DR: Experiments conducted under controlled conditions in vineyards and growth chambers demonstrated day- and night-specific responses of grape berry organic acid levels through altered TCA cycle and amino acid metabolism.
Abstract: Berries of the cultivated grapevine Vitis vinifera are notably responsive to temperature, which can influence fruit quality and hence the future compatibility of varieties with their current growing regions. Organic acids represent a key component of fruit organoleptic quality and their content is significantly influenced by temperature. The objectives of this study were to (i) manipulate thermal regimes to realistically capture warming-driven reduction of malate content in Shiraz berries, and (ii) investigate the mechanisms behind temperature-sensitive malate loss and the potential downstream effects on berry metabolism. In the field we compared untreated controls at ambient temperature with longer and milder warming (2–4 °C differential for three weeks; Experiment 1) or shorter and more severe warming (4–6 °C differential for 11 days; Experiment 2). We complemented field trials with control (25/15 °C) and elevated (35/20 °C) day/night temperature controlled-environment trials using potted vines (Experiment 3). Elevating maximum temperatures (4–10 °C above controls) during pre-veraison stages led to higher malate content, particularly with warmer nights. Heating at veraison and ripening stages reduced malate content, consistent with effects typically seen in warm vintages. However, when minimum temperatures were also raised by 4–6 °C, malate content was not reduced, suggesting that the regulation of malate metabolism differs during the day and night. Increased NADdependent malic enzyme activity and decreased phosphoenolpyruvate carboxylase and pyruvate kinase activities, as well as the accumulation of various amino acids and γ-aminobutyric acid, suggest enhanced anaplerotic capacity of the TCA cycle and a need for coping with decreased cytosolic pH in heated fruit.
162 citations
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TL;DR: CSLD is unacceptably common in indigenous children of this region, commences early in life, and is associated with significant comorbidities, particularly in children with chronic suppurative lung disease living in Central Australia.
Abstract: Childhood bronchiectasis not related to underlying disease is still common in some populations in affluent countries. The aims of the study were to: 1) describe demographics, 2) evaluate the effectiveness of routine investigations, and 3) determine the relationship between spirometry and radiology scoring systems, in children with chronic suppurative lung disease (CSLD) living in Central Australia. Data of children living in Central Australia aged 70%) and early hospitalisation for pneumonia were common (median age, 0.5 years). Previous admissions for pneumonia were almost universally present and significantly more common than bronchiolitis (95% CI for proportional difference, 0.4-0.51). Although the majority did not have a treatable underlying cause, investigations had significant impact on management in 12.3% of children. None of the chest HRCT scores related to any spirometry data. In conclusion, CSLD is unacceptably common in indigenous children of this region, commences early in life, and is associated with significant comorbidities. Spirometry data do not reflect the severity of lung disease in HRCT scans. While improvement in the living standards is of utmost importance, the medical management that includes thorough investigations of these children should not be neglected.
162 citations
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TL;DR: A correlated functional and structural circuitry of the submucous ganglia and their connections has been deduced and it is concluded that secretomotor reflexes are stimulated by the contents of the lumen during the digestion and absorption of food and that these reflexes cause a proportion of water and electrolytes that are absorbed with nutrients such as glucose to be returned to theLumen.
Abstract: Neither submucous ganglia, nor intestinal secretomotor reflexes are mentioned in the majority of the textbooks of physiology; because it has been realized only very recently that the submucous neurons may have important influences on whole body water and electrolyte balance. In the present review, we trace the rapid progress that has been made in determining the physiological properties of submucous neurons with known chemistry and projections in the guinea-pig small intestine, and we analyze how the work relates to studies in vivo of the neuronal control of intestinal trans-epithelial fluid transport. Four types of submucous neurons, which appear to be the full complement in the guinea-pig small intestine, have been identified through electrophysiological and histochemical analysis. (1) Cholinergic secretomotor neurons contain immunoreactivity for choline-acetyltransferase (ChAT), calcitonin gene-related peptide (CGRP), cholecystokinin (CCK), neuropeptide Y (NPY), somatostatin (SOM), and in the majority of cases galanin (GAL); these neurons project to the mucosal epithelium. (2) Non-cholinergic secretomotor neurons contain dynorphin (DYN), GAL and vasoactive intestinal peptide (VIP); these neurons project to the mucosa and provide collaterals to submucous arterioles. (3) Cholinergic interneurons contain ChAT alone; these neurons connect with the secretomotor neurons. (4) Presumed sensory neurons contain ChAT and substance P (SP) and have nerve endings in the mucosa. The two groups of secretomotor neurons receive cholinergic synaptic inputs from both myenteric and submucous ganglia. In addition, the DYN/GAL/VIP neurons receive sympathetic inhibitory inputs as well as inhibitory and non-cholinergic excitatory inputs from myenteric ganglia. The ChAT/SP nerve cells in submucous ganglia receive no or very ineffective inputs. From these data, from experiments on transmission from the neurons to the intestinal epithelium, and from studies of secretomotor reflexes in vivo, a correlated functional and structural circuitry of the submucous ganglia and their connections has been deduced. It is concluded that secretomotor reflexes are stimulated by the contents of the lumen during the digestion and absorption of food and that these reflexes cause a proportion of water and electrolytes that are absorbed with nutrients such as glucose to be returned to the lumen. The balance of absorption and secretion of water and electrolytes is controlled by sympathetic inhibitory inputs to secretomotor neurons, the activity in sympathetic pathways being varied to contribute to whole body water and electrolyte balance.
162 citations
Authors
Showing all 12221 results
Name | H-index | Papers | Citations |
---|---|---|---|
Matthew Jones | 125 | 1161 | 96909 |
Robert Edwards | 121 | 775 | 74552 |
Justin C. McArthur | 113 | 433 | 47346 |
Peter Somogyi | 112 | 232 | 42450 |
Glenda M. Halliday | 111 | 676 | 53684 |
Jonathan C. Craig | 108 | 872 | 59401 |
Bruce Neal | 108 | 561 | 87213 |
Alan Cooper | 108 | 746 | 45772 |
Robert J. Norman | 103 | 755 | 45147 |
John B. Furness | 103 | 597 | 37668 |
Richard J. Miller | 103 | 419 | 35669 |
Michael J. Brownstein | 102 | 274 | 47929 |
Craig S. Anderson | 101 | 650 | 49331 |
John Chalmers | 99 | 831 | 55005 |
Kevin D. Hyde | 99 | 1382 | 46113 |