Flinders University

About: Flinders University is a education organization based out in Adelaide, South Australia, Australia. It is known for research contribution in the topics: Population & Health care. The organization has 12033 authors who have published 32831 publications receiving 973172 citations. The organization is also known as: Flinders University of South Australia.

"Guess what I just heard!": Indirect aggression among teenage girls in Australia

Abstract: Traditionally males have been regarded as the more aggressive sex. However, recent research in several countries has challenged this notion by considering different forms of aggression. This paper provides an overview of a qualitative investigation of teenage girls' indirect forms of aggression (e.g,, exclusion from the group, spreading false stories), Focus groups and pair and individual interviews were used to collect data from adolescent girls and their teachers in two schools. The study provides some clear insights into the nature of teenage girls' indirect aggression. The predominant indirectly aggressive behaviors include talking about others and excluding peers from the group. Key explanations for these behaviors concern a desire to create excitement and a range of friendship and group processes centered on girls' needs for close personal relationships and to be a part of the peer group. The girls described the devastating effects of indirect aggression, particularly on girls with certain characteristics that predispose them to victimization. The girls were pessimistic about the potential of interventions, although peer mediation processes may be a way forward.

The transcriptional network that controls growth arrest and differentiation in a human myeloid leukemia cell line

Abstract: Using deep sequencing (deepCAGE), the FANTOM4 study measured the genome-wide dynamics of transcription-start-site usage in the human monocytic cell line THP-1 throughout a time course of growth arrest and differentiation. Modeling the expression dynamics in terms of predicted cis-regulatory sites, we identified the key transcription regulators, their time-dependent activities and target genes. Systematic siRNA knockdown of 52 transcription factors confirmed the roles of individual factors in the regulatory network. Our results indicate that cellular states are constrained by complex networks involving both positive and negative regulatory interactions among substantial numbers of transcription factors and that no single transcription factor is both necessary and sufficient to drive the differentiation process.

European guidelines for quality assurance in colorectal cancer screening and diagnosis : Overview and introduction to the full Supplement publication.

Abstract: Population-based screening for early detection and treatment of colorectal cancer (CRC) and precursor lesions, using evidence-based methods, can be effective in populations with a significant burden of the disease provided the services are of high quality. Multidisciplinary, evidence-based guidelines for quality assurance in CRC screening and diagnosis have been developed by experts in a project co-financed by the European Union. The 450-page guidelines were published in book format by the European Commission in 2010. They include 10 chapters and over 250 recommendations, individually graded according to the strength of the recommendation and the supporting evidence. Adoption of the recommendations can improve and maintain the quality and effectiveness of an entire screening process, including identification and invitation of the target population, diagnosis and management of the disease and appropriate surveillance in people with detected lesions. To make the principles, recommendations and standards in the guidelines known to a wider professional and scientific community and to facilitate their use in the scientific literature, the original content is presented in journal format in an open-access Supplement of Endoscopy. The editors have prepared the present overview to inform readers of the comprehensive scope and content of the guidelines.

The impact of comorbidity on cancer and its treatment

Abstract: Answer questions and earn CME/CNE Comorbidity is common among cancer patients and, with an aging population, is becoming more so. Comorbidity potentially affects the development, stage at diagnosis, treatment, and outcomes of people with cancer. Despite the intimate relationship between comorbidity and cancer, there is limited consensus on how to record, interpret, or manage comorbidity in the context of cancer, with the result that patients who have comorbidity are less likely to receive treatment with curative intent. Evidence in this area is lacking because of the frequent exclusion of patients with comorbidity from randomized controlled trials. There is evidence that some patients with comorbidity have potentially curative treatment unnecessarily modified, compromising optimal care. Patients with comorbidity have poorer survival, poorer quality of life, and higher health care costs. Strategies to address these issues include improving the evidence base for patients with comorbidity, further development of clinical tools to assist decision making, improved integration and coordination of care, and skill development for clinicians. CA Cancer J Clin 2016;66:337-350. © 2016 American Cancer Society.

NetGirls: The Internet, Facebook, and body image concern in adolescent girls

Abstract: Objective: The primary aim of the study was to examine the relationship between Internet exposure and body image concern in adolescent girls, with a particular focus on the social networking site of Facebook Method: As ample of 1,087 girls in the first two years (Years 8 and 9) of high school (aged 13‐15 years) completed questionnaire measures of Internet consumption and body image concerns Results: The overwhelming majority of girls (959%) had access to the Internet in their home Time spent on the Internet was significantly related to internalization of the thin ideal, body surveillance, and drive for thinness Further, 75% of the girls had a Facebook profile, and spent an average of 15 hours there daily Facebook users scored significantly more highly on all body image concern measures than non-users Discussion: It was concluded that the Internet represents a potent socio-cultural medium of relevance to the body image of adolescent girls