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Institution

Ford Motor Company

CompanyDearborn, Michigan, United States
About: Ford Motor Company is a company organization based out in Dearborn, Michigan, United States. It is known for research contribution in the topics: Internal combustion engine & Clutch. The organization has 36123 authors who have published 51450 publications receiving 855200 citations. The organization is also known as: Ford Motor & Ford Motor Corporation.


Papers
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Journal ArticleDOI
TL;DR: Early goal-directed therapy modulates systemic inflammation and results in significant reductions in morbidity, mortality, and healthcare resource consumption and has been externally validated and is generalizable across multiple healthcare settings.
Abstract: Purpose of reviewAggressive approaches to acute diseases such as acute myocardial infarction, trauma, and stroke have improved outcomes. Early goal-directed therapy for severe sepsis and septic shock represents a similar approach. An analysis of the literature assessing external validity and general

172 citations

Proceedings ArticleDOI
TL;DR: 50 years of publications on numerical modeling published in the Stapp Car Crash Conference Proceedings and Journal were reviewed and clearly indicates the progression of the state-of-the-art in computational methods and technologies in injury biomechanics.
Abstract: Numerical analyses frequently accompany experimental investigations that study injury biomechanics and improvements in automotive safety. Limited by computational speed, earlier mathematical models tended to simplify the system under study so that a set of differential equations could be written and solved. Advances in computing technology and analysis software have enabled the development of many sophisticated models that have the potential to provide a more comprehensive understanding of human impact response, injury mechanisms, and tolerance. In this article, 50 years of publications on numerical modeling published in the Stapp Car Crash Conference Proceedings and Journal were reviewed. These models were based on: (a) author-developed equations and software, (b) public and commercially available programs to solve rigid body dynamic models (such as MVMA2D, CAL3D or ATB, and MADYMO), and (c) finite element models. A clear trend that can be observed is the increasing use of the finite element method for model development. A review of these modeling papers clearly indicates the progression of the state-of-the-art in computational methods and technologies in injury biomechanics.

171 citations

Journal ArticleDOI
01 Sep 1999-Geoderma
TL;DR: In this article, variations of titanium concentrations within the soils were used to estimate rates of weathering of parent material, and the presence of newly generated anatase was recorded after the exposure periods, showing the rapidity of the processes.

171 citations

Journal ArticleDOI
TL;DR: The data suggest that in dogs with chronic HF, constituent myocytes of LV regions which manifest severe RIF may be subjected to chronic hypoxia; a condition that can adversely impact the function and viability of the collagen encircled cardiocyte.
Abstract: Progressive deterioration of left ventricular (LV) function is a characteristic feature of the heart failure (HF) state. The mechanism or mechanisms responsible for this hemodynamic deterioration are not known but may be related to progressive intrinsic dysfunction, degeneration and loss of viable cardiocytes. In the present study, we tested the hypothesis that accumulation of collagen in the cardiac interstitium (reactive interstitial fibrosis, RIF), known to occur in HF, results in reduced capillary density (CD=capillary/fiber ratio) and increased oxygen diffusion distance (ODD) which can lead to hypoxia and dysfunction of the collagen encircled myocyte. Studies were performed in LV tissue obtained from 10 dogs with chronic HF (LV ejection fraction 26±1%) produced by multiple sequential intracoronary, microembolizations. In each dog, CD and ODD were evaluated in LV regions that manifested severe RIF (volume fraction 16±2%) and in LV regions of little or no RIF (volume fraction 4±1%). In regions of severe RIF, CD was significantly decreased compared to regions of no RIF (0.92±0.02 vs. 1.05±0.03) (P<0.03). Similarly, ODD was significantly increased in regions of severe RIF compared to regions of no RIF (15.3±0.4 vs. 12.2±0.3 μm) (P<0.001). These data suggest that in dogs with chronic HF, constituent myocytes of LV regions which manifest severe RIF may be subjected to chronic hypoxia; a condition that can adversely impact the function and viability of the collagen encircled cardiocyte.

171 citations


Authors

Showing all 36140 results

NameH-indexPapersCitations
Anil K. Jain1831016192151
Markus Antonietti1761068127235
Christopher M. Dobson1501008105475
Jack Hirsh14673486332
Galen D. Stucky144958101796
Federico Capasso134118976957
Peter Stone130122979713
Gerald R. Crabtree12837160973
Douglas A. Lauffenburger12270555326
Abass Alavi113129856672
Mark E. Davis11356855334
Keith Beven11051461705
Naomi Breslau10725442029
Fei Wang107182453587
Jun Yang107209055257
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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
202237
2021766
20201,397
20192,195
20181,945
20171,995