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Institution

Ford Motor Company

CompanyDearborn, Michigan, United States
About: Ford Motor Company is a company organization based out in Dearborn, Michigan, United States. It is known for research contribution in the topics: Internal combustion engine & Signal. The organization has 36123 authors who have published 51450 publications receiving 855200 citations. The organization is also known as: Ford Motor & Ford Motor Corporation.


Papers
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Journal ArticleDOI
TL;DR: In this paper, three different inverters: conventional PWM, dc-dc boosted PWM and Z-source inverter were investigated and compared for fuel cell vehicle application, and an example of the total switching device power, requirement of passive components, the constant power speed ratio, and the efficiencies of the different in-vivo inverters for fuelcell vehicle powered by the same fuel cell were conducted.
Abstract: In this paper, three different inverters: conventional pulsewidth modulation (PWM) inverter, dc-dc boosted PWM inverter, and Z-source inverter were investigated and compared for fuel cell vehicle application. Total switching device power, passive components requirement, and constant power speed ratio of each of these inverters were calculated. For purposes of comparison, an example of the total switching device power, requirement of passive components, the constant power speed ratio, and the efficiencies of the different inverters for fuel cell vehicle powered by the same fuel cell were conducted. The comparisons show that the Z-source inverter is very promising in applications when the boost ratio is low (1-2).

430 citations

Journal ArticleDOI
TL;DR: Data indicate that atorvastatin promotes angiogenesis, brain plasticity and enhances functional recovery after stroke, and VEGF, VEGFR2 and BDNF likely contribute to these restorative processes.
Abstract: Molecular mechanisms underlying the role of statins in the induction of brain plasticity and subsequent improvement of neurologic outcome after treatment of stroke have not been adequately investigated. Here, we use both in vivo and in vitro studies to investigate the potential roles of two prominent factors, vascular endothelial growth factor (VEGF) and brain-derived neurotrophic factor (BDNF), in mediating brain plasticity after treatment of stroke with atorvastatin. Treatment of stroke in adult mice with atorvastatin daily for 14 days, starting at 24 hours after MCAO, shows significant improvement in functional recovery compared with control animals. Atorvastatin increases VEGF, VEGFR2 and BDNF expression in the ischemic border. Numbers of migrating neurons, developmental neurons and synaptophysin-positive cells as well as indices of angiogenesis were significantly increased in the atorvastatin treatment group, compared with controls. In addition, atorvastatin significantly increased brain subventricular zone (SVZ) explant cell migration in vitro. Anti-BDNF antibody significantly inhibited atorvastatin-induced SVZ explant cell migration, indicating a prominent role for BDNF in progenitor cell migration. Mouse brain endothelial cell culture expression of BDNF and VEGFR2 was significantly increased in atorvastatin-treated cells compared with control cells. Inhibition of VEGFR2 significantly decreased expression of BDNF in brain endothelial cells. These data indicate that atorvastatin promotes angiogenesis, brain plasticity and enhances functional recovery after stroke. In addition, VEGF, VEGFR2 and BDNF likely contribute to these restorative processes.

429 citations

Journal ArticleDOI
TL;DR: In this paper, an experimental and theoretical study has been carried out on the process of inelastic tunneling between metal films, which gives rise to the observation of vibrational spectra for molecules contained in the junction region.
Abstract: An experimental and theoretical study has been carried out on the process of inelastic tunneling between metal films. The experimental results show that this process gives rise to the observation of vibrational spectra for molecules contained in the junction region. The phenomena have been studied for a number of molecular species and at temperatures ranging from 1 to 300\ifmmode^\circ\else\textdegree\fi{}K. The principal effect of temperature is to broaden the observed spectral lines which can be accounted for quantitatively by considering the thermal smearing of the electron distribution in metals. Two detailed interaction mechanisms are discussed which can give rise to infrared dipole or Raman selection rules. None of the experiments carried out thus far can distinguish between these two processes, because of the low symmetry of the molecules used. In addition to the vibrational spectra, it appears that it should be possible to observe electronic transitions as well.

428 citations

Journal ArticleDOI
TL;DR: The goal is to offer a compromise between computing effort and design optimality, which has some advantages over the regular Latin hypercube design with respect to criteria such as entropy and the minimum intersite distance.

427 citations

Journal ArticleDOI
01 Sep 1998-Bone
TL;DR: It is concluded that rats can initiate haversian remodeling in long bones in response to fatigue, and that osteocyte death or damage may provide one of the stimuli for this process.

426 citations


Authors

Showing all 36140 results

NameH-indexPapersCitations
Anil K. Jain1831016192151
Markus Antonietti1761068127235
Christopher M. Dobson1501008105475
Jack Hirsh14673486332
Galen D. Stucky144958101796
Federico Capasso134118976957
Peter Stone130122979713
Gerald R. Crabtree12837160973
Douglas A. Lauffenburger12270555326
Abass Alavi113129856672
Mark E. Davis11356855334
Keith Beven11051461705
Naomi Breslau10725442029
Fei Wang107182453587
Jun Yang107209055257
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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
202237
2021766
20201,397
20192,195
20181,945
20171,995