Institution
Forest Research Institute
Facility•Dehra Dūn, India•
About: Forest Research Institute is a facility organization based out in Dehra Dūn, India. It is known for research contribution in the topics: Population & Forest management. The organization has 5320 authors who have published 7625 publications receiving 185876 citations.
Topics: Population, Forest management, Picea abies, Forest ecology, Scots pine
Papers published on a yearly basis
Papers
More filters
••
TL;DR: In this article, the authors systematically analyzed important components of vulnerability and mapped them by weight for four altitude zones in the Indian Himalayas, focusing on components of the three different dimensions of vulnerability (adaptive capacity, exposure, sensitivity) were identified based on the literature.
85 citations
••
TL;DR: Aclidinium is effective and well tolerated in patients with moderate to severe chronic obstructive pulmonary disease and time to first moderate or severe COPD exacerbation is significantly delayed in ACCLAIM/COPD II.
Abstract: Background: The long-term efficacy and safety of aclidinium bromide, a novel, long-acting muscarinic antagonist, were investigated in patients with moderate to severe chronic obstructive pulmonary disease (COPD). Methods: In two double-blind, 52-week studies, ACCLAIM/COPD I (n = 843) and II (n = 804), patients were randomised to inhaled aclidinium 200 μg or placebo once-daily. Patients were required to have a postbronchodilator forced expiratory volume in 1 second (FEV1)/forced vital capacity ratio of ≤70% and FEV1 <80% of the predicted value. The primary endpoint was trough FEV1 at 12 and 28 weeks. Secondary endpoints were health status measured by St George’s Respiratory Questionnaire (SGRQ) and time to first moderate or severe COPD exacerbation. Results: At 12 and 28 weeks, aclidinium improved trough FEV1 versus placebo in ACCLAIM/COPD I (by 61 and 67 mL; both p < 0.001) and ACCLAIM/COPD II (by 63 and 59 mL; both p < 0.001). More patients had a SGRQ improvement ≥4 units at 52 weeks with aclidinium versus placebo in ACCLAIM/COPD I (48.1% versus 39.5%; p = 0.025) and ACCLAIM/ COPD II (39.0% versus 32.8%; p = 0.074). The time to first exacerbation was significantly delayed by aclidinium in ACCLAIM/COPD II (hazard ratio [HR] 0.7; 95% confidence interval [CI] 0.55 to 0.92; p = 0.01), but not ACCLAIM/COPD I (HR 1.0; 95% CI 0.72 to 1.33; p = 0.9). Adverse events were minor in both studies. Conclusion: Aclidinium is effective and well tolerated in patients with moderate to severe COPD. Trial registration: ClinicalTrials.gov: NCT00363896 (ACCLAIM/COPD I) and NCT00358436 (ACCLAIM/COPD II).
85 citations
••
TL;DR: Milnacipran administered at a dosage of 100 mg/day improved pain, global status, fatigue, and physical and mental function in patients with fibromyalgia.
Abstract: Objective
To assess the efficacy and safety of milnacipran at a dosage of 100 mg/day (50 mg twice daily) for monotherapy treatment of fibromyalgia.
Methods
A double-blind, placebo-controlled trial was performed to assess 1,025 patients with fibromyalgia who were randomized to receive milnacipran 100 mg/day (n = 516) or placebo (n = 509). Patients underwent 4–6 weeks of flexible dose escalation followed by 12 weeks of stable-dose treatment. Two composite responder definitions were used as primary end points to classify the response to treatment. The 2-measure composite response required achievement of ≥30% improvement from baseline in the pain score and a rating of “very much improved” or “much improved” on the Patient's Global Impression of Change (PGIC) scale. The 3-measure composite response required satisfaction of these same 2 improvement criteria for pain and global status as well as improvement in physical function on the Short Form 36 (SF-36) physical component summary (PCS) score.
Results
After 12 weeks of stable-dose treatment, a significantly greater proportion of milnacipran-treated patients compared with placebo-treated patients showed clinically meaningful improvements, as evidenced by the proportion of patients meeting the 2-measure composite responder criteria (P < 0.001 in the baseline observation carried forward [BOCF] analysis) and 3-measure composite responder criteria (P < 0.001 in the BOCF). Milnacipran-treated patients also demonstrated significantly greater improvements from baseline on multiple secondary outcomes, including 24-hour and weekly recall pain score, PGIC score, SF-36 PCS and mental component summary scores, average pain severity score on the Brief Pain Inventory, Fibromyalgia Impact Questionnaire total score (all P < 0.001 versus placebo), and Multidimensional Fatigue Inventory total score (P = 0.036 versus placebo). Milnacipran was well tolerated by most patients, with nausea being the most commonly reported adverse event (placebo-adjusted rate of 15.8%).
Conclusion
Milnacipran administered at a dosage of 100 mg/day improved pain, global status, fatigue, and physical and mental function in patients with fibromyalgia.
85 citations
••
TL;DR: In this paper, the effect of binders on the durability of wood pellets was investigated, and it was shown that combining LP, Rapeseed flour, coffee meal, bark, pine cones, and lignin powder (LP) showed the most noticeable effect on increasing the durability.
85 citations
••
TL;DR: In this article, the properties, potential utilization, and problems of protecting rubberwood against sapstain, mold, and wood-decaying fungi are discussed, and advances in biological control, particularly biofungicides, are emphasized as an alternative method for rubberwood treatment.
Abstract: Rubber trees were introduced into the Malay Peninsula more than a century ago. The normal economical lifespan of a rubber tree is about 25 years, and, traditionally, rubberwood was used as firewood by the rural community. In recent decades, rubberwood has become an important timber for wood products, particularly in the furniture manufacturing sector, due to its attractive features, cream color, and good working properties. Sapstain, mold, and wooddecaying fungi are serious threats to rubberwood. Conventional chemical control has been a successful method of preventing staining fungal growth, but the effects of these chemicals are of concern because they create problems for the environment and public health. Thus, biological control has been recognized as an alternative approach to the problem. This article reviews the properties, potential utilization, and problems of protecting rubberwood against sapstain, mold, and wood-decaying fungi, and discusses the treatment methods available. Advances in biological control, particularly biofungicides, are emphasized as an alternative method for rubberwood treatment.
85 citations
Authors
Showing all 5332 results
Name | H-index | Papers | Citations |
---|---|---|---|
Kari Alitalo | 174 | 817 | 114231 |
Jaakko Kaprio | 163 | 1532 | 126320 |
Glenn D. Prestwich | 88 | 690 | 42758 |
John K. Volkman | 78 | 212 | 21931 |
Petri T. Kovanen | 77 | 432 | 27171 |
Hailong Wang | 69 | 647 | 19652 |
Mika Ala-Korpela | 65 | 319 | 18048 |
Heikki Henttonen | 64 | 271 | 14536 |
Zhihong Xu | 57 | 438 | 11832 |
Kari Pulkki | 54 | 215 | 11166 |
Louis A. Schipper | 53 | 192 | 9224 |
Sang Young Lee | 53 | 271 | 9917 |
Young-Joon Ahn | 52 | 288 | 9121 |
Venkatesh Narayanamurti | 49 | 258 | 9399 |
Francis M. Kelliher | 49 | 124 | 8599 |