Forest Research Institute

About: Forest Research Institute is a facility organization based out in Dehra Dūn, India. It is known for research contribution in the topics: Population & Forest management. The organization has 5320 authors who have published 7625 publications receiving 185876 citations.

Evaluation of Streptomyces sp. strain g10 for suppression of Fusarium wilt and rhizosphere colonization in pot-grown banana plantlets

Abstract: Streptomyces sp. strain g10 exhibited strong antagonism towards Fusarium oxysporum f.sp. cubense (Foc) races 1, 2 and 4 in plate assays by producing extracellular antifungal metabolites. Treating the planting hole and roots of 4-week-old tissue-culture-derived 'Novaria' banana plantlets with strain g10 suspension (10(8) cfu/ml), significantly (P < 0.05) reduced wilt severity when the plantlets were inoculated with 10(4) spores/ml Foc race 4. The final disease severity index for leaf symptom (LSI) and rhizome discoloration (RDI) was reduced about 47 and 53%, respectively, in strain g10-treated plantlets compared to untreated plantlets. Reduction in disease incidence was not significant (P < 0.05) when plantlets were inoculated with a higher concentration (10(6) spores/ml) of Foc race 4. Rhizosphere population of strain g10 showed significant (P = 0.05) increase of more than 2-fold at the end of the 3rd week compared to the 2nd week after soil amendment with the antagonist. Although the level dropped, the rhizosphere population at the end of the 6th week was still nearly 2-fold higher than the level detected after 2 weeks. In contrast, the root-free population declined significantly (P = 0.05), nearly 4-fold after 6 weeks when compared to the level detected after 2 weeks. Neither growth-inhibiting nor growth-stimulating effects were observed in plantlets grown in strain g10-amended soil.

Forests, trees and human health.

Abstract: The link between modern lifestyles and increasing levels of chronic heart disease, obesity, stress and poor mental health is a concern across the world. The cost of dealing with these conditions pl ...

Preliminary reconstructions of spring precipitation in southwestern Turkey from tree-ring width

Abstract: Two reconstructions of spring (May–June) precipitation have been developed for southwestern Turkey. The first reconstruction (1776–1998) was developed from principal components of nine chronologies of Cedrus libani, Juniperus excelsa, Pinus brutia ,a ndPinus nigra. The second reconstruction (1339–1998) was derived from principal components of three J. excelsa chronologies. Calibration and verification statistics of both reconstructions indicate reasonably accurate reconstruction of spring precipitation for southwestern Turkey, and show clear evidence of multi-year to decadal variations in spring precipitation. The longest period of reconstructed spring drought, defined as consecutive years with less than 80% of normal May–June precipitation, was 4 years (1476–79). Only one drought event of this duration has occurred during the last six centuries. Monte Carlo analysis indicates a less than 33% probability that southwestern Turkey has experienced spring drought longer than 5 years in the past 660 years. Apart from the 1476–79 extended dry period, spring droughts of 3 years in length have only occurred from 1700 to the present. The longest reconstructed wet period, defined as consecutive years with more than 120% of normal May–June precipitation, was 4 years (1532–35). The absence of extended spring drought during the 16th and 17th centuries and the occurrence of extended wet spring periods during these centuries suggest a possible regime shift in climate. Preliminary analysis of links between large-scale climatic variation and these climate reconstructions shows that there is a relationship between extremes in spring precipitation and anomalous atmospheric circulation in the region. Copyright  2003 Royal Meteorological Society.

Inhibition of c-kit tyrosine kinase by imatinib mesylate induces apoptosis in mast cells in rheumatoid synovia: a potential approach to the treatment of arthritis

Abstract: Background: Mast cells have been implicated in the pathogenesis of arthritis, but elucidation of their precise role has been hampered by a lack of efficient and selective inhibitors of their function. Objective: To elucidate the role of mast cells in the pathogenesis of rheumatoid arthritis (RA) and to assess whether apoptosis of cultured and synovial tissue mast cells can be induced by inhibiting mast cell growth factor receptor, c-kit tyrosine kinase. Methods and results: Double staining with tumour necrosis factor (TNF) α and tryptase antibodies showed the presence of TNFα positive mast cells in human rheumatoid synovial tissue. Selective activation of mast cells by anti-IgE resulted in production of TNFα in synovial tissue cultures. Inhibition of the c-kit tyrosine kinase with imatinib mesylate (1.0–10 μmol/l) induced profound apoptosis in cultured mast cells as judged by typical apoptotic morphology, increased number of apoptotic nucleosomes, and activation of caspases 8 and 9. Importantly, imatinib also induced apoptosis of mast cells in explant cultures of synovial tissue obtained from patients with RA as judged by a TUNEL assay. Inhibition of c-kit tyrosine kinase was accompanied by significant reduction of TNFα production in synovial tissue cultures. Conclusion: Mast cells may have a role in the pathogenesis of RA, and inhibition of c-kit may be a new means of inhibiting mast cell activity and of abrogating the contribution of mast cells to synovial inflammation in RA.