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Institution

Fu Jen Catholic University

EducationTaipei, Taiwan
About: Fu Jen Catholic University is a education organization based out in Taipei, Taiwan. It is known for research contribution in the topics: Population & Hazard ratio. The organization has 6842 authors who have published 9512 publications receiving 171005 citations. The organization is also known as: FJU & Fu Jen.


Papers
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Journal ArticleDOI
TL;DR: BAF1 exposure contributes to the development of HCC in participants with significant risk factors for cirrhosis including alcohol and HCV infection, and remained an independent risk predictor for HCV-related HCC after adjustment for other HCC predictors.

52 citations

Journal ArticleDOI
TL;DR: Results of this study demonstrate that stock cost and machine idle cost are inversely related to the number of lots split and have marginal decreasing result of benefit.

52 citations

Journal ArticleDOI
TL;DR: PGA-SPIONs modified with an edible biopolymer poly(γ-glutamic acid) (PGA) were synthesized by coprecipitation method and evaluated for their removal efficiency of heavy metals from a metal solution, and simulated gastrointestinal fluid (SGIF).
Abstract: Background: Chelation therapy involving organic chelators for treatment of heavy metal intoxication can cause cardiac arrest, kidney overload, mineral deficiency, and anemia.

52 citations

Journal ArticleDOI
15 Jun 2006-Synapse
TL;DR: The results suggest that nicotine exerts its potentiatory effect presynaptically, likely through the activation of α7 nicotinic receptors, resulting in Na+ influx and local depolarization, which subsequently enhances the CaK+ entry through voltage‐dependent N‐and P/Q‐type Ca2+ channels as well as the vesicular release machinery to cause an increase in evoked glutamate release from rat prefrontocortical nerve terminals.
Abstract: The effect of nicotine on evoked glutamate release from isolated nerve terminals (synaptosomes) from rat prefrontal cortex was examined. We found that nicotine significantly potentiated 4-aminopyridine (4AP)-evoked glutamate release, and this potentiatory effect was mimicked by the selective α7 nicotinic receptor agonist choline and was blocked by the selective α7 nicotinic receptor antagonist methyllycaconitine, indicating its mediation by α7 nicotinic receptors. Examination of the effect of nicotine on cytosolic [Ca2+] revealed that the potentiation of glutamate release was associated with an increase in voltage-dependent Ca2+ influx through N- and P/Q-type Ca2+ channels. The potentiatory effect of nicotine on Ca2+ influx seems to be attributed to its increasing synaptosomal excitability because nicotine significantly increased depolarization-evoked increase in the intrasynaptosomal free Na+ concentration and 4AP-evoked depolarization of the synaptosomal plasma membrane potential. Also, Ca2+ ionophore ionomycin-induced glutamate release was enhanced by nicotine, and this action was blocked by methyllycaconitine. These results suggest that nicotine exerts its potentiatory effect presynaptically, likely through the activation of α7 nicotinic receptors, resulting in Na+ influx and local depolarization, which subsequently enhances the CaK+ entry through voltage-dependent N-and P/Q-type Ca2+ channels as well as the vesicular release machinery to cause an increase in evoked glutamate release from rat prefrontocortical nerve terminals. Moreover, in this release potentiation may involve an activation of Ca2+/calmodulin signaling pathway as nicotine-mediated potentiation of 4AP- and ionomycin-evoked glutamate release were significantly attenuated by KN62, a selective inhibitor of Ca2+/calmodulin-dependent kinase II. Synapse 59:491–501, 2006. © 2006 Wiley-Liss, Inc.

52 citations

Journal ArticleDOI
TL;DR: The results suggest an important role of cSLNs in governing the activation of human neutrophils and the cytotoxicity, pro-inflammatory mediators, Ca(2+) mobilization, mitogen-activated protein kinases (MAPKs), and neutrophil extracellular traps (NETs) as the indicators of PMN stimulation were examined.

52 citations


Authors

Showing all 6861 results

NameH-indexPapersCitations
P. Chang1702154151783
Christian Guilleminault13389768844
Pan-Chyr Yang10278646731
Po-Ren Hsueh92103038811
Shyi-Ming Chen9042522172
Peter J. Rossky7428021183
Chong-Jen Yu7257722940
Shuu Jiun Wang7150224800
Jaw-Town Lin6743415482
Lung Chi Chen6326713929
Ronald E. Taam5929012383
Jiann T. Lin5819010801
Yueh-Hsiung Kuo5761812204
San Lin You5517816572
Liang-Gee Chen5458212073
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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
202313
202233
2021726
2020666
2019571
2018528