Institution
Fundación Instituto Leloir
Facility•Buenos Aires, Argentina•
About: Fundación Instituto Leloir is a facility organization based out in Buenos Aires, Argentina. It is known for research contribution in the topics: Dentate gyrus & Neurogenesis. The organization has 702 authors who have published 1052 publications receiving 39299 citations.
Topics: Dentate gyrus, Neurogenesis, RNA, Arabidopsis, Population
Papers published on a yearly basis
Papers
More filters
TL;DR: This work reports the crystal structure of the Brucella HK domain, which presents two different dimeric assemblies in the asymmetric unit: one similar to the already described canonical parallel homodimers (C) and the other, an antiparallel non-canonical (NC) dimer, each with distinct relative subdomain orientations and dimerization interfaces.
18 citations
TL;DR: Results demonstrate that GA treatment can reverse the learning impairment induced by stress through a mechanism that likely involves the regulation of the cytokine balance and adult neurogenesis.
Abstract: Long-term exposure to stressful situations has deleterious effects on adult neurogenesis, behavior, and the immune system. We have previously shown that stressed BALB/c mice show poor learning performance, which correlates with an increase in the T helper 1/T helper 2 (Th1/Th2) cytokine balance. Glatiramer acetate (GA) can stimulate autoreactive T cells. In this work we investigated the effects of GA treatment on BALB/c mice exposed to chronic mild stress (CMS). Stressed mice exhibited a significant decline in their performance in the open field and Y-maze tasks, which was accompanied by a reduction in dentate gyrus neurogenesis and an altered Th1/Th2 balance. Interestingly, after 6 weeks of CMS exposure administration of GA reestablished normal levels of adult neurogenesis, restored the Th1/Th2 balance, and improved learning performance. These results demonstrate that GA treatment can reverse the learning impairment induced by stress through a mechanism that likely involves the regulation of the cytokine balance and adult neurogenesis.
18 citations
18 citations
TL;DR: The correlation between the presence of some motifs and virus host specificity and tissue tropism suggests that linear motifs play a role in the adaptive evolution of papillomavirus types.
18 citations
TL;DR: Root hair growth dramatically expands the root surface area, thus facilitating water and nutrient uptake, and coordinates hormonal, environmental, and developmental factors to trigger polar growth.
18 citations
Authors
Showing all 707 results
| Name | H-index | Papers | Citations |
|---|---|---|---|
| Jorge J. Casal | 61 | 182 | 10814 |
| Silvia N.J. Moreno | 61 | 225 | 10585 |
| Won Sang Park | 58 | 227 | 10501 |
| Su Young Kim | 51 | 198 | 8829 |
| Marcelo J. Yanovsky | 44 | 93 | 7949 |
| Mario D. Galigniana | 40 | 99 | 5257 |
| Eduardo M. Castaño | 40 | 89 | 7125 |
| Andrea V. Gamarnik | 38 | 82 | 5896 |
| Osvaldo L. Podhajcer | 35 | 122 | 4996 |
| Alejandro F. Schinder | 34 | 64 | 10256 |
| Juliana Idoyaga | 32 | 63 | 5326 |
| Fernando Alberto Goldbaum | 32 | 103 | 3385 |
| Fernando Juan Pitossi | 31 | 65 | 4489 |
| Kevin Gaston | 29 | 78 | 2725 |
| Jong Woo Lee | 29 | 77 | 3453 |