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Showing papers by "Gadjah Mada University published in 2010"


Journal ArticleDOI
TL;DR: It is concluded that, for dental applications, antimicrobial coatings killing bacteria upon contact are more promising than antimicrobial-releasing coatings.
Abstract: Biomaterials for the restoration of oral function are prone to biofilm formation, affecting oral health. Oral bacteria adhere to hydrophobic and hydrophilic surfaces, but due to fluctuating shear, little biofilm accumulates on hydrophobic surfaces in vivo. More biofilm accumulates on rough than on smooth surfaces. Oral biofilms mostly consist of multiple bacterial strains, but Candida species are found on acrylic dentures. Biofilms on gold and amalgam in vivo are thick and fully covering, but barely viable. Biofilms on ceramics are thin and highly viable. Biofilms on composites and glass-ionomer cements cause surface deterioration, which enhances biofilm formation again. Residual monomer release from composites influences biofilm growth in vitro, but effects in vivo are less pronounced, probably due to the large volume of saliva into which compounds are released and its continuous refreshment. Similarly, conflicting results have been reported on effects of fluoride release from glass-ionomer cements. Finally, biomaterial-associated infection of implants and devices elsewhere in the body is compared with oral biofilm formation. Biomaterial modifications to discourage biofilm formation on implants and devices are critically discussed for possible applications in dentistry. It is concluded that, for dental applications, antimicrobial coatings killing bacteria upon contact are more promising than antimicrobial-releasing coatings.

399 citations


Journal ArticleDOI
TL;DR: In this paper, Fourier transform infrared (FTIR) spectroscopy has been used for analysis of extra virgin olive oil (EVOO) adulterated with palm oil (PO), and two multivariate calibrations, namely partial least square (PLS) and principle component regression (PCR), were optimized for constructing the calibration models, either for normal spectra or its first and second derivatives.

383 citations


Journal ArticleDOI
TL;DR: The INDEPTH WHO–SAGE collaboration demonstrates the value and future possibilities for this type of research in informing policy and planning for a number of countries.
Abstract: Background: Globally, ageing impacts all countries, with a majority of older persons residing in lower- and middle-income countries now and into the future. An understanding of the health and well-being of these ageing populations is important for policy and planning; however, research on ageing and adult health that informs policy predominantly comes from higher-income countries. A collaboration between the WHO Study on global AGEing and adult health (SAGE) and International Network for the Demographic Evaluation of Populations and Their Health in developing countries (INDEPTH), with support from the US National Institute on Aging (NIA) and the Swedish Council for Working Life and Social Research (FAS), has resulted in valuable health, disability and well-being information through a first wave of data collection in 2006-2007 from field sites in South Africa, Tanzania, Kenya, Ghana, Viet Nam, Bangladesh, Indonesia and India. Objective: To provide an overview of the demographic and health characteristics of participating countries, describe the research collaboration and introduce the first dataset and outputs. Methods: Data from two SAGE survey modules implemented in eight Health and Demographic Surveillance Systems (HDSS) were merged with core HDSS data to produce a summary dataset for the site-specific and cross-site analyses described in this supplement. Each participating HDSS site used standardised training materials and survey instruments. Face-to-face interviews were conducted. Ethical clearance was obtained from WHO and the local ethical authority for each participating HDSS site. Results: People aged 50 years and over in the eight participating countries represent over 15% of the current global older population, and is projected to reach 23% by 2030. The Asian HDSS sites have a larger proportion of burden of disease from non-communicable diseases and injuries relative to their African counterparts. A pooled sample of over 46,000 persons aged 50 and over from these eight HDSS sites was produced. The SAGE modules resulted in self-reported health, health status, functioning (from the WHO Disability Assessment Scale (WHODAS-II)) and well-being (from the WHO Quality of Life instrument (WHOQoL) variables). The HDSS databases contributed age, sex, marital status, education, socio-economic status and household size variables. Conclusion: The INDEPTH WHO-SAGE collaboration demonstrates the value and future possibilities for this type of research in informing policy and planning for a number of countries. This INDEPTH WHO- SAGE dataset will be placed in the public domain together with this open-access supplement and will be available through the GHA website (www.globalhealthaction.net) and other repositories. An improved dataset is being developed containing supplementary HDSS variables and vignette-adjusted health variables. This living collaboration is now preparing for a next wave of data collection. Keywords: ageing; survey methods; public health; burden of disease; demographic transition; disability; well-being; health status; INDEPTH WHO-SAGE (Published: 27 September 2010) Citation: Global Health Action Supplement 2, 2010. DOI: 10.3402/gha.v3i0.5302 Access the supplementary material to this article: INDEPTH WHO-SAGE questionnaire (including variants of vignettes), a data dictionary and a password-protected dataset (see Supplementary files under Reading Tools online). To obtain a password for the dataset, please send a request with ‘SAGE data’ as its subject, detailing how you propose to use the data, to global.health@epiph.umu.se

180 citations


Journal ArticleDOI
TL;DR: Key diabetes-related factors affect retinal microvascular geometry in young type 1 diabetes, even in those without evidence of retinopathy, and these early retinal alterations may be markers of diabetes microv vascular complications.
Abstract: OBJECTIVE To describe retinal microvascular geometric parameters in young patients with type 1 diabetes. RESEARCH DESIGN AND METHODS Patients with type 1 diabetes (aged 12–20 years) had clinical assessments and retinal photography following standardized protocol at a tertiary-care hospital in Sydney. Retinal microvascular geometry, including arteriolar and venular tortuosity, branching angles, optimality deviation, and length-to-diameter ratio (LDR), were measured from digitized photographs. Associations of these geometric characteristics with diabetes duration, A1C level, systolic blood pressure (SBP), and other risk factors were assessed. RESULTS Of 1,159 patients enrolled, 944 (81.4%) had gradable photographs and 170 (14.7%) had retinopathy. Older age was associated with decreased arteriolar ( P = 0.024) and venular ( P = 0.002) tortuosity, and female subjects had larger arteriolar branching angle than male subjects ( P = 0.03). After adjusting for age and sex, longer diabetes duration was associated with larger arteriolar branching angle ( P ≤ 0.001) and increased arteriolar optimality deviation ( P = 0.018), higher A1C was associated with increased arteriolar tortuosity (>8.5 vs. ≤8.5%, P = 0.008), higher SBP was associated with decreased arteriolar LDR ( P = 0.002), and higher total cholesterol levels were associated with increased arteriolar LDR ( P = 0.044) and decreased venular optimality deviation ( P = 0.044). These associations remained after controlling for A1C, retinal vessel caliber, and retinopathy status and were seen in subjects without retinopathy. CONCLUSIONS Key diabetes-related factors affect retinal microvascular geometry in young type 1 diabetes, even in those without evidence of retinopathy. These early retinal alterations may be markers of diabetes microvascular complications.

131 citations


Journal ArticleDOI
TL;DR: Investigating immediate repair bond strengths and failure types of resin composites with and without surface conditioning and characterize the interacting composite surfaces by their surface composition and roughness found that the surfaces were dominated by the resin matrix.

107 citations


Journal ArticleDOI
TL;DR: The aim of the study was to analyze the parents' reasons of abandonment and to ascertain the fate of children who abandoned treatment in a pediatric oncology centre in Yogyakarta, Indonesia.
Abstract: Background: Treatment refusal and abandonment are common causes of treatment failure in childhood acute lymphoblastic leukemia (ALL) in many developing countries. In most studies reasons for abandonment were based on the opinion of health-care providers (HCP), very few studies have focused on the parental point-of-view. Aims of the study were to analyze the parents' reasons of abandonment and to ascertain the fate of children who abandoned treatment in a pediatric oncology centre in Yogyakarta, Indonesia. Methods: We conducted home-visits to interview families of ALL patients, diagnosed between January 2004 and August 2007, who refused or abandoned treatment. Results: From January 2004 to August 2007, 159 patients were diagnosed with ALL of which 40 children (25%) refused or abandoned therapy. Thirty-seven (93%) of these children were home-visited. Reasons for abandonment were complex. Most parents mentioned several reasons. Financial and transportation difficulties were not the only, or even the main reasons, for abandonment. Belief of ALL incurability, experience of severe side effects and dissatisfaction with HCP were also important considerations. Most patients (64%) abandoned treatment during the diagnostic-evaluation or remission-induction phase. Of the 37 patients who refused or abandoned treatment, 26 (70%) children died, and 11 (30%) children were still alive, 2 of them more than 2 years after abandonment. Conclusions: Reducing treatment abandonment of childhood ALL in developing countries requires not only financial and transportation support, but also parental education, counseling and psychosocial support during therapy, improvement of quality-of-care and adequate management of side effects. Copyright © 2009 John Wiley & Sons, Ltd.

107 citations


Journal ArticleDOI
TL;DR: In this article, a multivariate calibration method, partial least square (PLS) and principal component regression (PCR), was used to construct the calibration models that correlate between actual and FTIR-predicted values of VCO contents in the mixtures at the FTIR spectral frequencies of 1,120-1,105 and 965-960 cm−1.
Abstract: Rapid Fourier transform infrared (FTIR) spectroscopy combined with attenuated total reflectance (ATR) was applied for quantitative analysis of virgin coconut oil (VCO) in binary mixtures with olive oil (OO) and palm oil (PO). The spectral bands correlated with VCO, OO, PO; blends of VCO and OO; VCO and PO were scanned, interpreted, and identified. Two multivariate calibration methods, partial least square (PLS) and principal component regression (PCR), were used to construct the calibration models that correlate between actual and FTIR-predicted values of VCO contents in the mixtures at the FTIR spectral frequencies of 1,120–1,105 and 965–960 cm−1. The calibration models obtained were cross validated using the “leave one out” method. PLS at these frequencies showed the best calibration model, in terms of the highest coefficient of determination (R2) and the lowest of root mean standard error of calibration (RMSEC) with R2 = 0.9992 and RMSEC = 0.756, respectively, for VCO in mixture with OO. Meanwhile, the R2 and RMSEC values obtained for VCO in mixture with PO were 0.9996 and 0.494, respectively. In general, FTIR spectroscopy serves as a suitable technique for determination of VCO in mixture with the other oils.

83 citations


01 Jan 2010
TL;DR: In this article, the authors investigate the implementation of performance measurement systems (PMSs) in Indonesian local government (ILG) using Smart PLS Couched within an institutional theory framework, it explores a conceptual model developed to explain the hypothesised relationships between technical and organisational factors and the development and use of performance indicators and accountability practices.
Abstract: Purpose: The purpose of this paper is to investigate the implementation of performance measurement systems (PMSs) in Indonesian local government (ILG) using Smart PLS Couched within an institutional theory framework, it explores a conceptual model developed to explain the hypothesised relationships between technical and organisational factors and the development and use of performance indicators and accountability practices Design/methodology/approach: Surveys were sent to senior finance officers in all local governments (457) across Indonesia with a response rate of 214 percent being achieved Smart PLS was used to assess the quality of the data and analyse the research model proposed Findings: Findings revealed that ILGs developed performance indicators more to fulfil regulatory requirements than to make their organisation more effective and efficient As a way of increasing the success of PMS implementation management commitment through good leadership was found to be a major contributor Coercive pressure from central government impacted on the result as did normative isomorphism by way of widespread training by universities (and others) and the subsequent sharing of this knowledge

74 citations


Journal ArticleDOI
TL;DR: In this article, an inverse model called TsuSedMod is applied to estimate both the minimum flow depth and speed by using the thickness and grain size distribution of a tsunami deposit.

71 citations


Journal ArticleDOI
TL;DR: In this paper, a Cd(II)-IIP imprinted mercapto-functionalized silica gel sorbent was synthesized via a surface imprinting technique for selective adsorbent in aqueous.

67 citations


Journal ArticleDOI
TL;DR: Various dispersants were evaluated for their potential to be used as biocompatible dispersants in the synthesis of biomimetic composites with a nanodispersed mineral phase and tribasic sodium citrate was selected as the most effective dispersant for the stabilization of calcium phosphate (CaP) suspensions.

Journal Article
TL;DR: The most prevalent cancer site in males is the lung, followed by the liver, colon or the prostate in the majority of cases, while breast and cervical cancers predominate in most female populations, however, there are interesting differences among the racial groups, particularly regarding the stomach.
Abstract: Malaysia, Brunei, Singapore, Indonesia, East Timor and the Philippines constitute peninsular and island South-East Asia. For reasons of largely shared ethnicity, with Chinese elements added to the basic Austromalaysian populations, as well as geographical contiguity, they can be usefully grouped together for studies of chronic disease prevalence and underlying risk factors. The fact of problems are shared in common, particularly regarding increasing cancer rates, underlines the necessity for a coordinated approach to research and development of control measures. To provide a knowledge base, the present review of available data for cancer registration, epidemiology and control was conducted. The most prevalent cancer site in males is the lung, followed by the liver, colon or the prostate in the majority of cases, while breast and cervical cancers predominate in most female populations. However, there are interesting differences among the racial groups, particularly regarding the stomach. General tendencies for increase in adenocarcinomas but decrease in squamous cell carcinomas and gastric cancer, point to change in environmental influence over time. Variation in risk factors depends to some extent on the level of economic development but overall the countries of the region face similar challenges in achieving effective cancer control. A major task is persuading the general populace of the efficacy of early detection and clinical treatment.

Journal ArticleDOI
TL;DR: Being female, old, unmarried and having low educational and socio-economic levels were significantly associated with poor self-reported QoL, health status and disability among older people in Purworejo District, Indonesia.
Abstract: Introduction: Increasing life expectancy and longevity for people in many highly populated low- and middleincome countries has led to an increase in the number of older people. The population aged 60 years and over in Indonesia is projected to increase from 8.4% in 2005 to 25% in 2050. Understanding the determinants of healthy ageing is essential in targeting health-promotion programmes for older people in Indonesia. Objective: To describe patterns of socio-economic and demographic factors associated with health status, and to identify any spatial clustering of poor health among older people in Indonesia. Methods: In 2007, the WHO Study on global AGEing and adult health (SAGE) was conducted among 14,958 people aged 50 years and over in Purworejo District, Central Java, Indonesia. Three outcome measures were used in this analysis: self-reported quality of life (QoL), self-reported functioning and disability, and overall health score calculated from self-reported health over eight health domains. The factors associated with each health outcome were identified using multivariable logistic regression. Purely spatial analysis using Poisson regression was conducted to identify clusters of households with poor health outcomes. Results: Women, older age groups, people not in any marital relationship and low educational and socioeconomic levels were associated with poor health outcomes, regardless of the health indices used. Older people with low educational and socio-economic status (SES) had 3.4 times higher odds of being in the worst QoL quintile (OR=3.35; 95% CI=2.73-4.11) as compared to people with high education and high SES. This disadvantaged group also had higher odds of being in the worst functioning and most disabled quintile (OR=1.67; 95% CI=1.35-2.06) and the lowest overall health score quintile (OR=1.66; 95% CI=1.36-2.03). Poor health and QoL are not randomly distributed among the population over 50 years old in Purworejo District, Indonesia. Spatial analysis showed that clusters of households with at least one member being in the worst quintiles of QoL, functioning and health score intersected in the central part of Purworejo District, which is a semi-urban area with more developed economic activities compared with other areas in the district. Conclusion: Being female, old, unmarried and having low educational and socio-economic levels were significantly associated with poor self-reported QoL, health status and disability among older people in Purworejo District. This study showed the existence of geographical pockets of vulnerable older people in Purworejo District, and emphasized the need to take immediate action to address issues of older people’s health and QoL. Keywords: adult health; health status; clustering; quality of life; disability; ageing; Purworejo; Indonesia; INDEPTH WHO-SAGE (Published: 27 September 2010) Citation: Global Health Action Supplement 2, 2010. DOI: 10.3402/gha.v3i0.2125 Access the supplementary material to this article: INDEPTH WHO-SAGE questionnaire (including variants of vignettes), a data dictionary and a password-protected dataset (see Supplementary files under Reading Tools online). To obtain a password for the dataset, please send a request with ‘SAGE data’ as its subject, detailing how you propose to use the data, to global.health@epiph.umu.se

Journal ArticleDOI
TL;DR: In this article, a landslide hazard and risk assessment that will be useful for risk prevention and landuse planning in the Menoreh Mountains in Yogyakarta has been presented to evaluate the ways to map landslide risk in order to improve the risk mitigation.
Abstract: The Menoreh Mountains in Yogyakarta are severely affected by landslides. Due to the high population densities, mass movements are generally damaging and fatal. More than other Javanese mountains, the Menoreh Mountains cumulate several factors causing landslides. Therefore, it is necessary to evaluate the ways to map landslide risk in order to improve the risk mitigation. The objectives of this paper are to provide landslide hazard and risk assessment that will be useful for risk prevention and landuse planning in the Menoreh Mountains. So far, risk management has been developed by the Research Centre for Disasters Gadjah Mada University in collaboration with the Regional Development Planner (BAPPEDA), which carries out fundamental and applied researches. The results of the studies have been integrated in the risk prevention and landuse planning in order to improve the integrated landslide mitigation programme.

Journal ArticleDOI
TL;DR: The existence of sex differences in self-reported health in low- and middle-income countries even after adjustments for differences in demographic and socio-economic factors was confirmed.
Abstract: Background: Declining rates of fertility and mortality are driving demographic transition in all regions of the world, leading to global population ageing and consequently changing patterns of global morbidity and mortality. Understanding sex-related health differences, recognising groups at risk of poor health and identifying determinants of poor health are therefore very important for both improving health trajectories and planning for the health needs of ageing populations. Objectives: To determine the extent to which demographic and socio-economic factors impact upon measures of health in older populations in Africa and Asia; to examine sex differences in health and further explain how these differences can be attributed to demographic and socio-economic determinants. Methods: A total of 46,269 individuals aged 50 years and over in eight Health and Demographic Surveillance System (HDSS) sites within the INDEPTH Network were studied during 2006-2007 using an abbreviated version of the WHO Study on global AGEing and adult health (SAGE) Wave I instrument The survey data were then linked to longitudinal HDSS background information. A health score was calculated based on self-reported health derived from eight health domains. Multivariable regression and post-regression decomposition provide ways of measuring and explaining the health score gap between men and women. Results: Older men have better self-reported health than older women. Differences in household socioeconomic levels, age, education levels, marital status and living arrangements explained from about 82% and 71% of the gaps in health score observed between men and women in South Africa and Kenya, respectively, to almost nothing in Bangladesh. Different health domains contributed differently to the overall health scores for men and women in each country. Conclusion: This study confirmed the existence of sex differences in self-reported health in low- and middleincome countries even after adjustments for differences in demographic and socio-economic factors. A decomposition analysis suggested that sex differences in health differed across the HDSS sites, with the greatest level of inequality found in Bangladesh. The analysis showed considerable variation in how differences in socio-demographic and economic characteristics explained the gaps in self-reported health observed between older men and women in African and Asian settings. The overall health score was a robust indicator of health, with two domains, pain and sleep/energy, contributing consistently across the HDSS sites. Further studies are warranted to understand other significant individual and contextual determinants to which these sex differences in health can be attributed. This will lay a foundation for a more evidence-based approach to resource allocation, and to developing health promotion programmes for older men and women in these settings. Keywords: ageing; survey methods; public health; burden of disease; demographic transition; disability; well-being; health status; INDEPTH WHO-SAGE (Published: 27 September 2010) Citation: Global Health Action Supplement 2, 2010. DOI: 10.3402/gha.v3i0.5420 Access the supplementary material to this article: INDEPTH WHO-SAGE questionnaire (including variants of vignettes), a data dictionary and a password-protected dataset (see Supplementary files under Reading Tools online). To obtain a password for the dataset, please send a request with ‘SAGE data’ as its subject, detailing how you propose to use the data, to global.health@epiph.umu.se

Journal ArticleDOI
TL;DR: The ct-DNA binding properties of methylene blue (MB) including binding constant, thermodynamic parameter and thermal denaturation (T(m)) have been systematically studied by spectrophotometric method and suggests that MB dye possibly binds to cT-DNA via electrostatic and intercalation modes.

Journal ArticleDOI
TL;DR: It is important for Indonesia to target nutrition intervention for female adolescents, pregnant woman to first 2 years of life, initiate nutrition education for school‐age children and disseminate Holistic Healthy Framework Approach with key message ‘Initiate healthier food choices’.
Abstract: Obesity is a major contributor to the global burden of chronic disease and disability. In developing countries like Indonesia, obesity often co-exists with undernutrition. Data from national basic health research 2007 showed that overnutrition was found among all age groups, on a double digit scale, with similar magnitude in urban and rural areas and higher prevalence in adult female. In contrary to 14% undernourished children under the age of 5 years, 12% of their counterparts were overnourished; for 6-14 years 10% vs. 6%; and for 15 years and above 15% vs. 19%. The purpose of the review is to raise awareness on the increasing obesity problem and to set recommendations to prevent obesity. Stunted adults in developing countries are 1.2 times more likely to be overweight than non-stunted adults. Approaches to overcoming obesity in adulthood emphasize dietary changes, increasing physical activity and behaviour modification. It is important for Indonesia to target nutrition intervention for female adolescents, pregnant woman to first 2 years of life, initiate nutrition education for school-age children and disseminate Holistic Healthy Framework Approach with key message 'Initiate healthier food choices'. Prompt Nutrition Guidelines and the use of lower body mass index cut-off should be considered.

Journal ArticleDOI
TL;DR: The results of user studies show that the use of transparent photomaps is more effective to complete group tasks to discuss, draw, and annotate their infrastructure problems and that a combination use of simple and advanced PGIS methods is necessary to be implemented to reach informed priority‐decision making.
Abstract: Public participation is required in neighborhood infrastructure planning and problem-solving. Although Participatory GIS methods are considered important to help urban community groups identify problems and express their needs and concerns, usable means to help groups produce their maps remain difficult to be realised. Further, an effective means to facilitate the integration of government spatial plans and participatory maps also remains unclear. This article addresses usability issues in participatory mapping activities by exploring group collaboration mechanics and accomplishing use assessments. The study aims at testing the usefulness and the impact of participatory mapping for community development. User studies including questionnaire surveys, interviews, group usability testing, scenario assessments, and the scaling-up activity were executed. Transparent photomaps, Mobile GIS, and a Web map were implemented and assessed in the study area. A use scenario for community and official spatial data integration was also developed. The results of user studies show that the use of transparent photomaps is more effective to complete group tasks to discuss, draw, and annotate their infrastructure problems. For group participants, the transparent maps are more engaging, easy to learn, and more error tolerant than the use of Mobile GIS. A combination use of simple and advanced PGIS methods is necessary to be implemented to reach informed priority-decision making.

Journal ArticleDOI
TL;DR: In this paper, the authors presented the utility of remote sensing (RS), GIS and field observation data to estimate above ground biomass (AGB) and stem volume over tropical forest environment.
Abstract: This study presents the utility of remote sensing (RS), GIS and field observation data to estimate above ground biomass (AGB) and stem volume over tropical forest environment. Application of those data for the modeling of forest properties is site specific and highly uncertain, thus further study is encouraged. In this study we used 1460 sampling plots collected in 16 transects measuring tree diameter (DBH) and other forest properties which were useful for the biomass assessment. The study was carried out in tropical forest region in East Kalimantan, Indonesia. The AGB density was estimated applying an existing DBH — biomass equation. The estimate was superimposed over the modified GIS map of the study area, and the biomass density of each land cover was calculated. The RS approach was performed using a subset of sample data to develop the AGB and stem volume linear equation models. Pearson correlation statistics test was conducted using ETM bands reflectance, vegetation indices, image transform layers, Principal Component Analysis (PCA) bands, Tasseled Cap (TC), Grey Level Co-Occurrence Matrix (GLCM) texture features and DEM data as the predictors. Two linear models were generated from the significant RS data. To analyze total biomass and stem volume of each land cover, Landsat ETM images from 2000 and 2003 were preprocessed, classified using maximum likelihood method, and filtered with the majority analysis. We found 158±16 m3·ha−1 of stem volume and 168±15 t·ha−1 of AGB estimated from RS approach, whereas the field measurement and GIS estimated 157±92 m3·ha−1 and 167±94 t·ha−1 of stem volume and AGB, respectively. The dynamics of biomass abundance from 2000 to 2003 were assessed from multi temporal ETM data and we found a slightly declining trend of total biomass over these periods. Remote sensing approach estimated lower biomass abundance than did the GIS and field measurement data. The earlier approach predicted 10.5 Gt and 10.3 Gt of total biomasses in 2000 and 2003, while the later estimated 11.9 Gt and 11.6 Gt of total biomasses, respectively. We found that GLCM mean texture features showed markedly strong correlations with stem volume and biomass.

Journal ArticleDOI
TL;DR: It was revealed that several coating process-related factors such as thickness, post-heat treatment and deposition parameters, to name a few, affect its scratching behavior and several modes of failure occurred during the scratching process.
Abstract: It is generally accepted that calcium phosphate (CaP) is one of the most important biomaterials in implant coating applications mainly because of its excellent bioactivity. However, its relatively poor mechanical properties limits its application. This entails that a better understanding of the mechanical properties of a CaP coating is a must especially its behavior and the mechanisms involved when subjected to stresses which eventually lead to failure. The mechanical properties of the coating may be evaluated in terms of its adhesion strength. In this study, a radio frequency-magnetron (RF-MS) sputtering technique was used to deposit CaP thin films on 316L stainless steel (SS). The coatings were subjected to series of microscratch tests, taking careful note of its behavior as the load is applied. The adhesion behavior of the coatings showed varying responses. It was revealed that several coating process-related factors such as thickness, post-heat treatment and deposition parameters, to name a few, affect its scratching behavior. Scratch testing-related factors (i.e. loading rate, scratch speed, scratch load, etc.) were also shown to influence the mechanisms involved in the coating adhesion failure. Evaluation of the load-displacement graph combined with optical inspection of the scratch confirmed that several modes of failure occurred during the scratching process. These include trackside cracking, tensile cracking, radial cracking, buckling, delamination and combinations of one or more modes.

Journal ArticleDOI
TL;DR: In this paper, aluminum pillared montmorillonite was used as a porous support for the synthesis of TiO2-based photocatalysts with varying TiO 2 loading and the titania content in the composites significantly influenced the physicochemical properties and catalytic activity.

Journal ArticleDOI
TL;DR: Investigating whether low serum albumin levels are associated with adverse outcomes in acute coronary syndrome found that hypoalbuminemia did not predict independently in-hospital adverse outcomes, and interacted with other predictors, especially Killip class II-IV, which was consistently an independent predictor of in- hospital adverse outcomes.
Abstract: Epidemiological studies have demonstrated an association between low serum albumin levels and coronary heart disease and mortality. Nevertheless, the impact of a low serum albumin level during acute coronary syndrome has not yet been established. The aim of the present study was to investigate whether low serum albumin levels are associated with adverse outcomes in acute coronary syndrome. We enrolled 82 consecutive patients with acute coronary syndrome from whom venous blood for serum albumin measurement was drawn immediately upon hospital admission. Thirty-five patients had a low albumin level (hypoalbuminemia) and 47 had a normal albumin level (normoalbuminemia). In-hospital adverse outcomes (death, acute heart failure, cardiogenic shock, and reinfarction) were recorded during hospitalization in the intensive coronary care unit. The results of our study showed that the incidence of in-hospital adverse outcomes was 43%, with death occurring in 8 patients (10%). In-hospital adverse outcomes occurred more frequently in patients presenting with hypoalbuminemia, whereas mortality did not differ significantly. Univariate analysis showed that hypoalbuminemia was associated with a 2.8-fold greater risk of developing adverse outcomes. This risk was greater in the subgroup of NSTEACS (5.4-fold increased risk), but not in those with STEMI. Adjustment with other covariates revealed that hypoalbuminemia did not predict independently in-hospital adverse outcomes. It interacted with other predictors, especially Killip class II-IV, which was consistently an independent predictor of in-hospital adverse outcomes.

Journal ArticleDOI
TL;DR: In 2008, virus-like symptoms of yellowing, interveinal chlorosis, leaf curling and necrotic fleck were observed on greenhouse-tomato plants in Tochigi Prefecture, indicating that the virus was ToCV, that has not previously been reported in Japan.
Abstract: In 2008, virus-like symptoms of yellowing, interveinal chlorosis, leaf curling and necrotic fleck were observed on greenhouse-tomato plants (Solanum esculentum) in Tochigi Prefecture. The symptomatology and the characteristics of the causal agent such as whitefly transmissibility and particle morphology are similar to those for Tomato infectious chlorosis virus (TICV) and Tomato chlorosis virus (ToCV), species of the genus Crinivirus in the family Closteroviridae. Sequencing of reverse transcription-polymerase chain reaction (RT-PCR) products using the degenerate primers for heat shock protein 70 homolog genes of closteroviruses and specific primers for TICV and ToCV indicated that the virus was ToCV, that has not previously been reported in Japan.

Journal ArticleDOI
TL;DR: In this paper, the effect of added Ca-hydroxide to gypsum, carbonation periods, and hydrothermal temperatures for phosphatization was investigated to understand the basic principle of composition-transformation of gypsuma added Cahydroxides to fabricate CHA bone substitutes.

Journal ArticleDOI
TL;DR: The analysis finds that the program improved the nutritional status of treated children, and most significantly, led to 7 and 15 percent declines in rates of moderate and severe stunting, respectively, for children aged 12 to 24 months who were exposed to the program for at least 12 months over two years.

Journal ArticleDOI
TL;DR: In this paper, the authors investigate whether, and how, the use of performance measures, procedural justice, and interpersonal trust interact to affect organisational commitment of police officers, and they find that trust between an officer and his superior mediates the relationship between use of non-financial measures and organizational commitment but procedural justice does not have a mediating effect on commitment.
Abstract: This study aims to investigate whether, and how, the use of performance measures, procedural justice, and interpersonal trust interact to affect organisational commitment of police officers. Drawing on a survey based on a sample of 57 senior officers within a single police force, we find that the use of performance measures, procedural justice, and interpersonal trust are positively associated with organisational commitment. Further analysis reveals that trust between officer and superior mediates the relationship between the use of non-financial measures and organisational commitment, but procedural justice does not have a mediating effect on commitment. These findings are further explored through selected interviews with respondents.

Journal ArticleDOI
TL;DR: It is concluded that in vitro exposure to oral biofilm is a clinically relevant aging condition, and that silica-coating is to be preferred for the repair of aged composites.
Abstract: Composite restorations degrade during wear, but it is unknown how wear affects the composite surface and influences composite-to-composite bonding in minimally invasive repair. Here, it is hypothesized that in vitro exposure of composites to oral biofilm yields clinically relevant degradation of composite surfaces, and its influence on composite-to-composite bonding is determined. Biofilms on composite surfaces in vitro increased their roughness and decreased filler particle exposure, except for a microhybrid composite, similar to effects of clinical wear in palatal appliances. Failure shear stresses after intermediate-adhesive-resin application were significantly lower after aging by in vitro exposure to biofilms, while silica-coating maintained the same failure stress levels as in non-aged composites. Failure modes were predominantly cohesive after silica-coating, while intermediate-adhesive-resin application yielded more adhesive failure. It is concluded that in vitro exposure to oral biofilm is a clinically relevant aging condition, and that silica-coating is to be preferred for the repair of aged composites.

Proceedings ArticleDOI
15 Jun 2010
TL;DR: The architecture and VHDL design of 2-D DCT, combined with quantization and zig-zag arrangement, is described in this paper and aimed to be implemented in cheap Spartan-3E XC3S500 FPGA.
Abstract: Two dimensional DCT takes important role in JPEG image compression. Architecture and VHDL design of 2-D DCT, combined with quantization and zig-zag arrangement, is described in this paper. The architecture is used in JPEG image compression. DCT calculation used in this paper is made using scaled DCT. The output of DCT module needs to be multiplied with post-scaler value to get the real DCT coefficients. Post-scaling process is done together with quantization process. 2-D DCT is computed by combining two 1-D DCT that connected by a transpose buffer. This design aimed to be implemented in cheap Spartan-3E XC3S500 FPGA. The 2-D DCT architecture uses 3174 gates, 1145 Slices, 21 I/O pins, and 11 multipliers of one Xilinx Spartan-3E XC3S500E FPGA and reaches an operating frequency of 84.81 MHz. One input block with 8×8 elements of 8 bits each is processed in 2470 ns and pipeline latency is 123 clock cycles.

Journal ArticleDOI
TL;DR: Ranging patterns of wild orangutans, overcrowding in captivity and a shift of age composition in favour of immatures seemed to be the most likely factors leading to these results.
Abstract: Faecal samples from 163 captive and semi-captive individuals, 61 samples from wild individuals and 38 samples from captive groups of Bornean orangutans (Pongo pygmaeus) in Kalimantan, Indonesia, were collected during one rainy season (November 2005-May 2006) and screened for intestinal parasites using sodium acetate-acetic acid-formalin-concentration (SAFC), sedimentation, flotation, McMaster- and Baermann techniques. We aimed to identify factors influencing infection risk for specific intestinal parasites in wild orangutans and individuals living in captivity. Various genera of Protozoa (including Entamoeba, Endolimax, Iodamoeba, Balantidium, Giardia and Blastocystis), nematodes (such as Strongyloides, Trichuris, Ascaris, Enterobius, Trichostrongylus and hookworms) and one trematode (a dicrocoeliid) were identified. For the first time, the cestode Hymenolepis was detected in orangutans. Highest prevalences were found for Strongyloides (individuals 37%; groups 58%), hookworms (41%; 58%), Balantidium (40%; 61%), Entamoeba coli (29%; 53%) and a trichostrongylid (13%; 32%). In re-introduction centres, infants were at higher risk of infection with Strongyloides than adults. Infection risk for hookworms was significantly higher in wild males compared with females. In groups, the centres themselves had a significant influence on the infection risk for Balantidium. Ranging patterns of wild orangutans, overcrowding in captivity and a shift of age composition in favour of immatures seemed to be the most likely factors leading to these results.

Journal ArticleDOI
TL;DR: Interestingly, a strong and positive significant correlation between neutrophil count and circulating sCD40L level is observed in unstable angina, indicating that Circulating s CD40L is associated with neutrophils count and may mediate interaction between neutophils and platelets in acute coronary syndrome, particularly in unstableAngina.
Abstract: Following plaque rupture, activated platelet will induce subsequent inflammatory process including neutrophil recruitment. In vitro study demonstrated an interaction between neutrophils and platelets via a mechanism involving CD40-CD40 ligand. However, whether this mechanism exists in the clinical setting remains unknown. Fifty-four patients with acute myocardial infarction (AMI) and 25 with unstable angina of pain onset of ≤24 h were enrolled consecutively. Acute myocardial infarction was diagnosed from three diagnostic criteria, i.e., anginal pain, electrocardiogram ST-T changes, and cardiac enzyme elevation. Unstable angina was diagnosed in patients without elevated cardiac enzymes. Peripheral venous blood was drawn at admission for routine blood count and soluble CD40 ligand (sCD40L) measurement. Neutrophil count was determined by an automated blood cell counter. Circulating sCD40L was measured using a standard enzyme-linked immunosorbent assay. Neutrophil count was significantly higher in AMI as compared with unstable angina (P < 0.001), whereas circulating sCD40L did not significantly differ. Despite marked elevation, no correlation was observed between neutrophil count and circulating sCD40L in AMI. Interestingly, we observed a strong and positive significant correlation between neutrophil count and circulating sCD40L level (r = 0.607, P = 0.002) in unstable angina. Circulating sCD40L is associated with neutrophil count and may mediate interaction between neutrophils and platelets in acute coronary syndrome, particularly in unstable angina.