Institution
Gadjah Mada University
Education•Yogyakarta, Indonesia•
About: Gadjah Mada University is a education organization based out in Yogyakarta, Indonesia. It is known for research contribution in the topics: Population & Adsorption. The organization has 17307 authors who have published 21389 publications receiving 116561 citations. The organization is also known as: University of Gajah Mada & Universitas Gadjah Mada.
Topics: Population, Adsorption, Tourism, Government, Catalysis
Papers published on a yearly basis
Papers
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TL;DR: This review provides a complete review related to structure, origin, and how the body responds to this virus infection and explains the possibility of an immune system over-reaction or cytokine storm.
Abstract: Background and aim As a result of its rapid spread in various countries around the world, on March 11, 2020, WHO issued an announcement of the change in coronavirus disease 2019 status from epidemic to pandemic disease. The virus that causes this disease is indicated originating from animals traded in a live animal market in Wuhan, China. Severe Acute Respiratory Syndrome Coronavirus 2 can attack lung cells because there are many conserved receptor entries, namely Angiotensin Converting Enzyme-2. The presence of this virus in host cells will initiate various protective responses leading to pneumonia and Acute Respiratory Distress Syndrome. This review aimed to provide an overview related to this virus and examine the body’s responses and possible therapies. Method We searched PubMed databases for Severe Acute Respiratory Syndrome Coronavirus-2, Middle East respiratory syndrome-related coronavirus and Severe Acute Respiratory Syndrome Coronavirus. Full texts were retrieved, analyzed and developed into an easy-to-understand review. Results We provide a complete review related to structure, origin, and how the body responds to this virus infection and explain the possibility of an immune system over-reaction or cytokine storm. We also include an explanation of how this virus creates modes of avoidance to evade immune system attacks. We further explain the therapeutic approaches that can be taken in the treatment and prevention of this viral infection. Conclusion In summary, based on the structural and immune-evasion system of coronavirus, we suggest several approaches to treat the disease.
745 citations
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TL;DR: The overall prevalence of absolute poverty in these countries was 14% higher than conventional estimates that do not take account of out-of-pocket payments for health care, and policies to reduce the number of Asians living on less than 1 dollar per day need to include measures to reduce such payments.
682 citations
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University of Western Australia1, Université du Québec à Montréal2, Ghent University3, Hogeschool-Universiteit Brussel4, Buskerud and Vestfold University College5, Université de Montréal6, ETH Zurich7, Gadjah Mada University8, University of Sheffield9, Pantheon-Assas University10, Cheikh Anta Diop University11, University of Toulouse12
TL;DR: In this article, a multidimensional work motivation scale was developed and tested using data from 3435 workers in seven languages and nine countries and the results indicated that the 19-item scale has the same factor structure across the seven languages.
Abstract: Self-determination theory proposes a multidimensional conceptualization of motivation comprising autonomous and controlled forms. Whereas autonomous motivation relates positively to individuals’ optimal functioning (e.g., well-being, performance), controlled motivation is less beneficial. To be able to use self-determination theory in the field of organizational behaviour, the Multidimensional Work Motivation Scale was developed and tested using data from 3435 workers in seven languages and nine countries. Factorial analyses indicated that the 19-item scale has the same factor structure across the seven languages. Convergent and discriminant validity tests across the countries also indicate that the psychological needs for autonomy, competence, and relatedness as well as the theoretically derived antecedents to work motivation (e.g., leadership and job design) are predictably related to the different forms of motivation, which in turn are predictably related to important work outcomes (e.g., well-being, commitment, performance, and turnover intentions). Implications for the development of organizational research based on self-determination theory are discussed.
622 citations
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TL;DR: Rice FT homologue Hd3a interacts with 14-3-3 proteins in the apical cells of shoots, yielding a complex that translocates to the nucleus and binds to the Oryza sativa transcription factor, a rice homologue of Arabidopsis thaliana FD.
Abstract: Florigen, a plant hormone that translocates from leaves to the shoot apex to induce flowering, is encoded by the FLOWERING LOCUS T (FT) gene. The detailed molecular mechanism for florigen action and the identity of its receptors remained unknown. Ko Shimamoto and colleagues show that in rice, florigen binds to 14-3-3 proteins, a type of regulatory molecule present in all eukaryotic cells, and to the transcription factor OsFD1. The crystal structure of the resulting florigen activation complex (FAC) has been determined, providing a mechanistic basis for florigen function in flowering. This work offers clues for improving agriculturally important traits by manipulating florigen and its regulators. ‘Florigen’ was proposed 75 years ago1 to be synthesized in the leaf and transported to the shoot apex, where it induces flowering. Only recently have genetic and biochemical studies established that florigen is encoded by FLOWERING LOCUS T (FT), a gene that is universally conserved in higher plants2,3,4. Nonetheless, the exact function of florigen during floral induction remains poorly understood and receptors for florigen have not been identified. Here we show that the rice FT homologue Hd3a5 interacts with 14-3-3 proteins in the apical cells of shoots, yielding a complex that translocates to the nucleus and binds to the Oryza sativa (Os)FD1 transcription factor, a rice homologue of Arabidopsis thaliana FD. The resultant ternary ‘florigen activation complex’ (FAC) induces transcription of OsMADS15, a homologue of A. thaliana APETALA1 (AP1), which leads to flowering. We have determined the 2.4 A crystal structure of rice FAC, which provides a mechanistic basis for florigen function in flowering. Our results indicate that 14-3-3 proteins act as intracellular receptors for florigen in shoot apical cells, and offer new approaches to manipulate flowering in various crops and trees.
562 citations
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TL;DR: This work estimates the magnitude and distribution of OOP payments for health care in fourteen countries and territories accounting for 81% of the Asian population and focuses on payments that are catastrophic, in the sense of severely disrupting household living standards, and approximate such payments by those absorbing a large fraction of household resources.
Abstract: Out-of-pocket (OOP) payments are the principal means of financing health care throughout much of Asia. We estimate the magnitude and distribution of OOP payments for health care in fourteen countries and territories accounting for 81% of the Asian population. We focus on payments that are catastrophic, in the sense of severely disrupting household living standards, and approximate such payments by those absorbing a large fraction of household resources. Bangladesh, China, India, Nepal and Vietnam rely most heavily on OOP financing and have the highest incidence of catastrophic payments. Sri Lanka, Thailand and Malaysia stand out as low to middle income countries that have constrained both the OOP share of health financing and the catastrophic impact of direct payments. In most low/middle-income countries, the better-off are more likely to spend a large fraction of total household resources on health care. This may reflect the inability of the poorest of the poor to divert resources from other basic needs and possibly the protection of the poor from user charges offered in some countries. But in China, Kyrgyz and Vietnam, where there are no exemptions of the poor from charges, they are as, or even more, likely to incur catastrophic payments.
561 citations
Authors
Showing all 17450 results
Name | H-index | Papers | Citations |
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Rob Cramb | 31 | 130 | 3201 |
Carlito Baltazar Tabelin | 30 | 93 | 2490 |
J.R. van Horn | 30 | 62 | 3005 |
Ymkje Stienstra | 30 | 122 | 3423 |
Hisahide Nishio | 30 | 213 | 3637 |
Christoph Gutenbrunner | 29 | 232 | 3621 |
Prashant K. Sharma | 29 | 109 | 3407 |
Romana Schirhagl | 28 | 87 | 3886 |
Jurgen Neuberg | 28 | 75 | 2619 |
Abdul Rohman | 28 | 399 | 4031 |
Muhammad Kamal | 27 | 150 | 3377 |
Naoki Yoshioka | 27 | 143 | 2481 |
Abdul Wahab | 27 | 274 | 2573 |
I. Bing Tan | 26 | 45 | 1905 |
Ahmad Maryudi | 26 | 88 | 1633 |