Institution
Gadjah Mada University
Education•Yogyakarta, Indonesia•
About: Gadjah Mada University is a education organization based out in Yogyakarta, Indonesia. It is known for research contribution in the topics: Population & Adsorption. The organization has 17307 authors who have published 21389 publications receiving 116561 citations. The organization is also known as: University of Gajah Mada & Universitas Gadjah Mada.
Topics: Population, Adsorption, Tourism, Government, Catalysis
Papers published on a yearly basis
Papers
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TL;DR: Recommendations to improve the regular use of moisturizers among AD patients include measures that focus on treatment compliance, patient and caregiver education, appropriate treatment goals, avoidance of sensitizing agents, and collaboration with other relevant specialists.
Abstract: Effective management of atopic dermatitis (AD) involves the treatment of a defective skin barrier. Patients with AD are therefore advised to use moisturizers regularly. To date, there are few comparative studies involving moisturizers in patients with AD, and no classification system exists to objectively determine which types of moisturizers are best suited to specific AD phenotypes. With this in mind, a group of experts from allergy and immunology, adult and pediatric dermatology, and pediatrics centers within Southeast Asia met to review current data and practice, and to develop recommendations regarding the use of moisturizers in patients with AD within the Asia-Pacific region. Chronicity and severity of AD, along with patient age, treatment compliance, and economic background should all be taken into account when selecting an appropriate moisturizer for AD patients. Other considerations include adjuvant properties of the product, cosmetic acceptability, and availability over the counter. Well-defined clinical phenotypes of AD could optimally benefit from specific moisturizers. It is hoped that future studies may identify such differences by means of filaggrin mutation subtypes, confocal microscopic evaluation, pH, transepidermal water loss or presence of allergy specific IgE. Recommendations to improve the regular use of moisturizers among AD patients include measures that focus on treatment compliance, patient and caregiver education, appropriate treatment goals, avoidance of sensitizing agents, and collaboration with other relevant specialists.
45 citations
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TL;DR: The results indicated that nanoindentation and nanoscratch experiments are acceptable methods for measuring the mechanical and tribologocal properties of a commercial hydroxyapatite (HA).
45 citations
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TL;DR: The synthesis of triacetin from glycerol and acetic acid using sulfuric acid catalyst has been performed in batch and continuous process, and the production using continuous reactive distillation resulted in Glycerol conversion of 98.51% and 8.84% of Triacetin selectivity.
Abstract: Biodiesel production from vegetable oil produces glycerol as by-product with the amount of about 10 wt% of its product. This excessive amount of glycerol needs to be converted into the higher valuable product. One of the prospective glycerol’s derivatives is triacetin, a good bio-additive as anti-knocking agent. The synthesis of triacetin from glycerol and acetic acid using sulfuric acid catalyst has been performed in batch and continuous process. In this work, triacetin was synthesized using batch reactor to give 96.30% of glycerol conversion and 20.50% of triacetin selectivity. Meanwhile, the production using continuous reactive distillation resulted in glycerol conversion of 98.51% and 8.84% of triacetin selectivity.
45 citations
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TL;DR: In this article, the authors investigate the factors determining the social and environmental reporting of Indian textile and apparel (TA) firms, and report a low extent of SER in the annual reports of Indian listed TA firms, with a mean disclosure of 14 percent.
Abstract: Purpose – The purpose of this research is to investigate the factors determining the social and environmental reporting (SER) of Indian textile and apparel (TA) firms. Design/methodology/approach – The 2010 annual reports of a sample of top 100 Indian TA firms listed on the Bombay Stock Exchange were examined to assess the extent of SER. SER was assessed based on the Global Reporting Initiative index applicable to the TA industry. Multiple regression analysis was conducted to investigate the determinants of SER. Findings – This study reports a low extent of SER in the annual reports of Indian listed TA firms, with a mean disclosure of 14 per cent. On average, firms reported more extensive environmental information, with a mean disclosure of 18.4 per cent, compared to social information, with a mean disclosure of 10.7 per cent. Most firms reported social information relating to “labour practices and decent work”, while the reporting of information relating to “human rights” was sparse. Overall, the SER pat...
45 citations
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Charles Darwin University1, University of Melbourne2, Columbia University3, University of Khartoum4, Mahidol University5, Nangarhar University6, Liverpool School of Tropical Medicine7, Oswaldo Cruz Foundation8, University of Western Australia9, University of California, San Francisco10, Centers for Disease Control and Prevention11, Walter and Eliza Hall Institute of Medical Research12, Papua New Guinea Institute of Medical Research13, Curtin University14, Pasteur Institute15, University of North Sumatra16, Universidade Federal de Rondônia17, Gadjah Mada University18, University of Washington19, University of Indonesia20, University of Oxford21, Gleneagles Hospital22
TL;DR: The risk of recurrent P. vivax recurrence at day 42 is observed to be significantly lower following treatment with DP compared with AL, reflecting the longer period of post-treatment prophylaxis; this risk was reduced substantially by coadministration with PQ.
Abstract: BACKGROUND
Artemisinin-based combination therapy (ACT) is recommended for uncomplicated Plasmodium vivax malaria in areas of emerging chloroquine resistance. We undertook a systematic review and individual patient data meta-analysis to compare the efficacies of dihydroartemisinin-piperaquine (DP) and artemether-lumefantrine (AL) with or without primaquine (PQ) on the risk of recurrent P. vivax.
METHODS AND FINDINGS
Clinical efficacy studies of uncomplicated P. vivax treated with DP or AL and published between January 1, 2000, and January 31, 2018, were identified by conducting a systematic review registered with the International Prospective Register of Systematic Reviews (PROSPERO): CRD42016053310. Investigators of eligible studies were invited to contribute individual patient data that were pooled using standardised methodology. The effect of mg/kg dose of piperaquine/lumefantrine, ACT administered, and PQ on the rate of P. vivax recurrence between days 7 and 42 after starting treatment were investigated by Cox regression analyses according to an a priori analysis plan. Secondary outcomes were the risk of recurrence assessed on days 28 and 63. Nineteen studies enrolling 2,017 patients were included in the analysis. The risk of recurrent P. vivax at day 42 was significantly higher in the 384 patients treated with AL alone (44.0%, 95% confidence interval [CI] 38.7-49.8) compared with the 812 patients treated with DP alone (9.3%, 95% CI 7.1-12.2): adjusted hazard ratio (AHR) 12.63 (95% CI 6.40-24.92), p < 0.001. The rates of recurrence assessed at days 42 and 63 were associated inversely with the dose of piperaquine: AHRs (95% CI) for every 5-mg/kg increase 0.63 (0.48-0.84), p = 0.0013 and 0.83 (0.73-0.94), p = 0.0033, respectively. The dose of lumefantrine was not significantly associated with the rate of recurrence (1.07 for every 5-mg/kg increase, 95% CI 0.99-1.16, p = 0.0869). In a post hoc analysis, in patients with symptomatic recurrence after AL, the mean haemoglobin increased 0.13 g/dL (95% CI 0.01-0.26) for every 5 days that recurrence was delayed, p = 0.0407. Coadministration of PQ reduced substantially the rate of recurrence assessed at day 42 after AL (AHR = 0.20, 95% CI 0.10-0.41, p < 0.001) and at day 63 after DP (AHR = 0.08, 95% CI 0.01-0.70, p = 0.0233). Results were limited by follow-up of patients to 63 days or less and nonrandomised treatment groups.
CONCLUSIONS
In this study, we observed the risk of P. vivax recurrence at day 42 to be significantly lower following treatment with DP compared with AL, reflecting the longer period of post-treatment prophylaxis; this risk was reduced substantially by coadministration with PQ. We found that delaying P. vivax recurrence was associated with a small but significant improvement in haemoglobin. These results highlight the benefits of PQ radical cure and also the provision of blood-stage antimalarial agents with prolonged post-treatment prophylaxis.
45 citations
Authors
Showing all 17450 results
Name | H-index | Papers | Citations |
---|---|---|---|
Bunsho Ohtani | 71 | 371 | 19052 |
Lawrence H. Moulton | 71 | 266 | 20663 |
John M. Nicholls | 66 | 231 | 19014 |
Paul Meredith | 59 | 308 | 15489 |
Bernd M. Rode | 52 | 441 | 11367 |
Jan-Willem C. Alffenaar | 43 | 294 | 6378 |
Bernd Lehmann | 41 | 218 | 6027 |
Nawi Ng | 39 | 152 | 4470 |
Jean-Philippe Gastellu-Etchegorry | 38 | 192 | 4860 |
Mohd Hamdi | 38 | 190 | 5846 |
Keiko Sasaki | 36 | 319 | 5341 |
Jos G. W. Kosterink | 36 | 167 | 5132 |
A. C. Hayward | 34 | 106 | 6538 |
Eileen S. Scott | 33 | 177 | 3187 |
Michael R. Dove | 33 | 142 | 4334 |