Institution
Gadjah Mada University
Education•Yogyakarta, Indonesia•
About: Gadjah Mada University is a education organization based out in Yogyakarta, Indonesia. It is known for research contribution in the topics: Population & Adsorption. The organization has 17307 authors who have published 21389 publications receiving 116561 citations. The organization is also known as: University of Gajah Mada & Universitas Gadjah Mada.
Topics: Population, Adsorption, Tourism, Government, Catalysis
Papers published on a yearly basis
Papers
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TL;DR: In the last 10 years, dengue publications’ growth from Indonesia in international journals improved significantly, despite less number of publications compared to other SEA countries, which should be made to improve the quantity and quality of publications from Indonesia.
Abstract: Background: Dengue fever is a mosquito-borne viral disease with high incidence in over 128 countries. WHO estimates 500,000 people with severe dengue are hospitalized annually and 2.5% of those aff...
34 citations
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TL;DR: Results strongly suggested that cellular interaction between cancer cells and MSCs in the PDAC stroma might be critical to cancer progression, especially in the process of local invasion and the early stage development of metastasis.
Abstract: Pancreatic ductal adenocarcinoma (PDAC) is currently one of the most intractable malignancies with a typical scirrhous pattern in histology. Due to its abundant tumor stroma and scant vascularization, chemotherapeutic agents are considered inefficiently permeable to cancer nests, making it highly difficult to cure the patients with PDAC. However, PDAC is also considered to owe its intractability to other critical factors such as cellular interaction between tumor cells and tumor microenvironment as well as architectural barriers, which increases in therapeutic resistance. Here, we report a specific cellular interaction between PDAC cells and mesenchymal stem cells (MSCs) intermingled in PDAC stroma, which facilitates cancer invasion. Secretory phenotype profiling revealed that production of Amphiregulin (AREG) and MMP-3 were specifically upregulated under the coexistence of BxPC3 cells with human MSCs (approximately four to ten folds in AREG, and twenty to sixty-folds in MMP-3 compared to that of BxPC3 cells alone), whereas MMP-9 expression was decreased (less than one-tenth comparing with that of BxPC3 cells alone). Blockage of AREG production by its specific siRNA removed MSC-mediated driving force of BxPC3 invasiveness. Immunohistochemical analysis of tissue samples obtained both from PDAC patients and PDAC imitating mouse xenografted models revealed that significant coexpression of AREG and its receptor EGFR were detected on the cancer cells at invasive front. These results strongly suggested that cellular interaction between cancer cells and MSCs in the PDAC stroma might be critical to cancer progression, especially in the process of local invasion and the early stage development of metastasis.
34 citations
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TL;DR: In this article, Fourier transform infrared spectroscopy using attenuated total reflectance in combination with chemometrics techniques of partial least squares and principal component regression is implemented to construct the quantification and classification models of palm oil and canola oil in avocado oil.
Abstract: Avocado oil is one of the functional oils having high quality and high price in the market. This oil shows many benefits for the human health and is applied in many cosmetic products. The authentication of avocado oil becomes very important due to the possible adulteration of avocado oil with other lower priced oils, such as palm oil and canola oil. In this study, Fourier transform infrared spectroscopy using attenuated total reflectance in combination with chemometrics techniques of partial least squares and principal component regression is implemented to construct the quantification and classification models of palm oil and canola oil in avocado oil. Partial least squares at the wavenumbers region of 1260–900 cm–1 revealed the best calibration models, having the highest coefficient of determination (R2 = 0.999) and the lowest root mean square error of calibration, 0.80%, and comparatively low root mean square error of prediction, 0.79%, for analysis of avocado oil in the mixture with palm oil. Meanwhil...
34 citations
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TL;DR: To investigate physiological effects of Ce³+ on microorganisms, a free-living soil bacterium that produced exopolysaccharide (EPS) around its colonies was isolated and was found to be structurally similar to rhamnans.
34 citations
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TL;DR: The proposed time-variant input models were superior to the constant input models and appropriately converged to the observed data of GRF and R-apomorphine allowing the estimation of Jss, KR, and Jpas, and in most cases, the values of tL were negligible.
Abstract: Purpose. The objective of this study was to develop a family of compartmental models to describe in a strictly quantitative manner the transdermal iontophoretic transport of drugs in vitro.
34 citations
Authors
Showing all 17450 results
Name | H-index | Papers | Citations |
---|---|---|---|
Bunsho Ohtani | 71 | 371 | 19052 |
Lawrence H. Moulton | 71 | 266 | 20663 |
John M. Nicholls | 66 | 231 | 19014 |
Paul Meredith | 59 | 308 | 15489 |
Bernd M. Rode | 52 | 441 | 11367 |
Jan-Willem C. Alffenaar | 43 | 294 | 6378 |
Bernd Lehmann | 41 | 218 | 6027 |
Nawi Ng | 39 | 152 | 4470 |
Jean-Philippe Gastellu-Etchegorry | 38 | 192 | 4860 |
Mohd Hamdi | 38 | 190 | 5846 |
Keiko Sasaki | 36 | 319 | 5341 |
Jos G. W. Kosterink | 36 | 167 | 5132 |
A. C. Hayward | 34 | 106 | 6538 |
Eileen S. Scott | 33 | 177 | 3187 |
Michael R. Dove | 33 | 142 | 4334 |