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Institution

Gadjah Mada University

EducationYogyakarta, Indonesia
About: Gadjah Mada University is a education organization based out in Yogyakarta, Indonesia. It is known for research contribution in the topics: Population & Adsorption. The organization has 17307 authors who have published 21389 publications receiving 116561 citations. The organization is also known as: University of Gajah Mada & Universitas Gadjah Mada.
Topics: Population, Adsorption, Tourism, Government, Catalysis


Papers
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Journal ArticleDOI
TL;DR: In this paper, Fourier transform infrared (FTIR) spectroscopy has been used for analysis of extra virgin olive oil (EVOO) adulterated with palm oil (PO), and two multivariate calibrations, namely partial least square (PLS) and principle component regression (PCR), were optimized for constructing the calibration models, either for normal spectra or its first and second derivatives.

383 citations

Journal ArticleDOI
TL;DR: A set of drug-use indicators produced and tested in twelve developing countries are presented and described, which include the use of indicators to increase awareness among prescribers in Malawi and Bangladesh, and to identify priorities for action.

315 citations

Journal ArticleDOI
TL;DR: This work estimates the distributional incidence of health care financing in 13 Asian territories that account for 55% of the Asian population and finds that in most low-/middle-income countries, the better-off not only pay more, they also get more health care.

304 citations

Journal ArticleDOI
TL;DR: The studies indicate that the CMAH gene was inactivated shortly before the time when brain expansion began in humankind's ancestry, ≈2.1–2.2 mya.
Abstract: Humans are genetically deficient in the common mammalian sialic acid N-glycolylneuraminic acid (Neu5Gc) because of an Alu-mediated inactivating mutation of the gene encoding the enzyme CMP-N-acetylneuraminic acid (CMP-Neu5Ac) hydroxylase (CMAH). This mutation occurred after our last common ancestor with bonobos and chimpanzees, and before the origin of present-day humans. Here, we take multiple approaches to estimate the timing of this mutation in relationship to human evolutionary history. First, we have developed a method to extract and identify sialic acids from bones and bony fossils. Two Neandertal fossils studied had clearly detectable Neu5Ac but no Neu5Gc, indicating that the CMAH mutation predated the common ancestor of humans and Neandertals, ≈0.5–0.6 million years ago (mya). Second, we date the insertion event of the inactivating human-specific sahAluY element that replaced the ancestral AluSq element found adjacent to exon 6 of the CMAH gene in the chimpanzee genome. Assuming Alu source genes based on a phylogenetic tree of human-specific Alu elements, we estimate the sahAluY insertion time at ≈2.7 mya. Third, we apply molecular clock analysis to chimpanzee and other great ape CMAH genes and the corresponding human pseudogene to estimate an inactivation time of ≈2.8 mya. Taken together, these studies indicate that the CMAH gene was inactivated shortly before the time when brain expansion began in humankind's ancestry, ≈2.1–2.2 mya. In this regard, it is of interest that although Neu5Gc is the major sialic acid in most organs of the chimpanzee, its expression is selectively down-regulated in the brain, for as yet unknown reasons.

303 citations

Journal ArticleDOI
13 Dec 1996-Science
TL;DR: Electron spin resonance (ESR) and mass spectrometric U-series dating of fossil bovid teeth collected from the hominid-bearing levels at these sites gave mean ages of 27 ± 2 to 53.3 ± 4 thousand years ago; the range in ages reflects uncertainties in uranium migration histories.
Abstract: Hominid fossils from Ngandong and Sambungmacan, Central Java, are considered the most morphologically advanced representatives of Homo erectus. Electron spin resonance (ESR) and mass spectrometric U-series dating of fossil bovid teeth collected from the hominid-bearing levels at these sites gave mean ages of 27 +/- 2 to 53.3 +/- 4 thousand years ago; the range in ages reflects uncertainties in uranium migration histories. These ages are 20,000 to 400,000 years younger than previous age estimates for these hominids and indicate that H. erectus may have survived on Java at least 250,000 years longer than on the Asian mainland, and perhaps 1 million years longer than in Africa. The new ages raise the possibility that H. erectus overlapped in time with anatomically modern humans (H. sapiens) in Southeast Asia.

287 citations


Authors

Showing all 17450 results

NameH-indexPapersCitations
Bunsho Ohtani7137119052
Lawrence H. Moulton7126620663
John M. Nicholls6623119014
Paul Meredith5930815489
Bernd M. Rode5244111367
Jan-Willem C. Alffenaar432946378
Bernd Lehmann412186027
Nawi Ng391524470
Jean-Philippe Gastellu-Etchegorry381924860
Mohd Hamdi381905846
Keiko Sasaki363195341
Jos G. W. Kosterink361675132
A. C. Hayward341066538
Eileen S. Scott331773187
Michael R. Dove331424334
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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
202346
2022201
20212,264
20203,105
20192,810
20182,588