Gdańsk Medical University

About: Gdańsk Medical University is a education organization based out in Gdańsk, Poland. It is known for research contribution in the topics: Population & Cancer. The organization has 4893 authors who have published 11216 publications receiving 260523 citations.

Prevalence and risk factors of anabolic-androgenic steroids (AAS) abuse among adolescents and young adults in Poland.

Abstract: Objective To estimate the prevalence of anabolic-androgenic steroids (AAS) abuse among adolescent and young adults in Poland.

The ERA-EDTA Registry Annual Report 2017: a summary

Abstract: Background This article presents a summary of the 2017 Annual Report of the European Renal Association-European Dialysis and Transplant Association (ERA-EDTA) Registry and describes the epidemiology of renal replacement therapy (RRT) for end-stage renal disease (ESRD) in 37 countries Methods The ERA-EDTA Registry received individual patient data on patients undergoing RRT for ESRD in 2017 from 32 national or regional renal registries and aggregated data from 21 registries The incidence and prevalence of RRT, kidney transplantation activity and survival probabilities of these patients were calculated Results In 2017, the ERA-EDTA Registry covered a general population of 694 million people The incidence of RRT for ESRD was 127 per million population (pmp), ranging from 37 pmp in Ukraine to 252 pmp in Greece A total of 62% of patients were men, 52% were ≥65 years of age and 23% had diabetes mellitus as the primary renal disease The treatment modality at the onset of RRT was haemodialysis for 85% of patients On 31 December 2017, the prevalence of RRT was 854 pmp, ranging from 210 pmp in Ukraine to 1965 pmp in Portugal The transplant rate in 2017 was 33 pmp, ranging from 3 pmp in Ukraine to 103 pmp in the Spanish region of Catalonia For patients commencing RRT during 2008-12, the unadjusted 5-year patient survival probability for all RRT modalities combined was 508%

How does the type of vehicle influence the in vitro skin absorption and elimination kinetics of terpenes

Abstract: Terpenes are widely used in the topical dermal preparations, cosmetics and toiletries and also in the experimental dermopharmacy, as penetration enhancers. Terpenes do not need to penetrate into viable skin tissue and this event is not even desired. The aim of this study was to investigate skin absorption and elimination kinetics of two terpenes, namely linalool and terpinen-4-ol, incorporated in three different dermatological vehicles: oily solution, hydrogel and o/w emulsion. The preparations were applied onto the human skin in vitro, and after 1–4 h the content of terpenes in the stratum corneum layers and in the epidermis/dermis was determined using GC. Similarly, the amounts of terpenes in the skin were analysed during 4 h elimination process following 1 h absorption. The highest skin absorption was observed when terpenes were applied in hydrogel — their total content in the skin after 4 h was 385 and 705 μg/cm2 for linalool and terpinen-4-ol, respectively. After 1 h of the elimination process about 10–20% drop of the total content of both terpenes in the skin was noted for all formulations. The skin penetration of both terpenes from the vehicles is increasing in the following order: emulsion < oily solution < hydrogel, while the elimination phase is relatively slower for terpenes applied in hydrogel.

Quality of life in Polish patients with long‐lasting Parkinson's disease

Abstract: The objective of this study was to evaluate possible relationships between quality of life (QoL) of Polish patients with long-lasting Parkinson's disease and various demographic and clinical factors. The study comprised 141 patients of Movement Disorders outpatient clinics in Warsaw and Gdansk with at least 5 years of the disease duration. Mean age of patients was 68.09 ± 8.51 years, mean duration of disease was 11.87 ± 5.14 years. To assess the quality of life, the Parkinson's Disease Questionnaire (PDQ-39) was used. Additional questions concerned duration of disease, initial and current treatment and expenses associated with therapy. Self-perceived symptoms of depression were in our study the most important factor determining QoL. Duration of the disease and expenses related to the treatment also have a significant impact on the QoL. Patient's age and presence of dyskinesia seem to be irrelevant to the quality of life. © 2003 Movement Disorder Society