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Institution

Gdańsk Medical University

EducationGdańsk, Poland
About: Gdańsk Medical University is a education organization based out in Gdańsk, Poland. It is known for research contribution in the topics: Population & Cancer. The organization has 4893 authors who have published 11216 publications receiving 260523 citations.


Papers
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Journal ArticleDOI
TL;DR: The International Association for the Study of Lung Cancer (IASLC) liquid biopsy statement as mentioned in this paper revisited the role of liquid-biopsy in therapeutic decision-making in a recent workshop in October 2020 and the question of "plasma first" versus "tissue first" approach toward molecular testing for advanced NSCLC.

186 citations

Journal ArticleDOI
TL;DR: In this article, the authors analyzed sediment samples from the Gulf of Gdansk and the southern Baltic Sea and found that up to 45% of the total Cu was extracted from the sediments by 0.1 M NaOH and appears to be associated with the humic acid fraction.

186 citations

Journal ArticleDOI
TL;DR: The ability to inactivate AHL (quorum quenching, QQ) might be useful in controlling virulence of many pathogenic bacteria.
Abstract: Many Gram-positive and Gram-negative bacteria communicate using small diffusible signal molecules called autoinducers. This process, known as quorum sensing (QS), links cell density to the expression of genes as diverse as those associated with virulence factors production of plant and animal pathogens, bioluminescence, antibiotic production, sporulation or biofilm formation. In Gram-negative bacteria, this communication is mainly mediated by N-acyl-homoserine lactones (AHLs). It has been proven that inactivation of the signal molecules attenuates many of the processes controlled by QS. Enzymatic degradation of the signal molecules has been amply described. Two main classes of AHL-inactivating enzymes were identified: AHL lactonases which hydrolyse the lactone ring in AHLs, and AHL acylases (syn. AHL amidases) which liberate a free homoserine lactone and a fatty acid. Recently, AHL oxidoreductase, a novel type of AHL inactivating enzyme, was described. The activity of these enzymes results in silencing the QS-regulated processes, as degradation products cannot act as signal molecules. The ability to inactivate AHL (quorum quenching, QQ) might be useful in controlling virulence of many pathogenic bacteria.

185 citations

Journal ArticleDOI
TL;DR: In this paper, a review of the theoretical background of QSRR and its application in the search for new reliable and precise descriptors of the structures of solutes of relevance to their properties, including properties other than chromatographic, e.g., bioactivity.

185 citations


Authors

Showing all 4927 results

NameH-indexPapersCitations
Magdi H. Yacoub109126752431
Virend K. Somers10661554203
Felix Mitelman9557835416
Andrzej Slominski9146927900
Nils Mandahl8642725006
Fredrik Mertens8440628705
Enriqueta Felip8362253364
Pieter E. Postmus8138424039
Wilhelm Kriz7322219335
Godefridus J. Peters7352328315
Jacek Jassem7360235976
Piotr Rutkowski7256342218
Thomas Frodl7025816469
Eric J. Velazquez7039627539
Argye E. Hillis6839822230
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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
202317
202264
20211,092
20201,004
2019863
2018802