Institution
Georgia Institute of Technology
Education•Atlanta, Georgia, United States•
About: Georgia Institute of Technology is a education organization based out in Atlanta, Georgia, United States. It is known for research contribution in the topics: Population & Nonlinear system. The organization has 45387 authors who have published 119086 publications receiving 4651220 citations.
Topics: Population, Nonlinear system, Control theory, Finite element method, Artificial neural network
Papers published on a yearly basis
Papers
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TL;DR: An overview of some of the developments in the formulation of ARCH models and a survey of the numerous empirical applications using financial data can be found in this paper, where several suggestions for future research, including the implementation and tests of competing asset pricing theories, market microstructure models, information transmission mechanisms, dynamic hedging strategies, and pricing of derivative assets, are also discussed.
4,206 citations
TL;DR: This paper presents a detailed study on recent advances and open research issues in WMNs, followed by discussing the critical factors influencing protocol design and exploring the state-of-the-art protocols for WMNs.
4,205 citations
TL;DR: In this article, the Streptococcus pyogenes Cas9 (SpCas9) nuclease can be efficiently targeted to genomic loci by means of single-guide RNAs (sgRNAs) to enable genome editing.
Abstract: The Streptococcus pyogenes Cas9 (SpCas9) nuclease can be efficiently targeted to genomic loci by means of single-guide RNAs (sgRNAs) to enable genome editing. Here, we characterize SpCas9 targeting specificity in human cells to inform the selection of target sites and avoid off-target effects. Our study evaluates >700 guide RNA variants and SpCas9-induced indel mutation levels at >100 predicted genomic off-target loci in 293T and 293FT cells. We find that SpCas9 tolerates mismatches between guide RNA and target DNA at different positions in a sequence-dependent manner, sensitive to the number, position and distribution of mismatches. We also show that SpCas9-mediated cleavage is unaffected by DNA methylation and that the dosage of SpCas9 and sgRNA can be titrated to minimize off-target modification. To facilitate mammalian genome engineering applications, we provide a web-based software tool to guide the selection and validation of target sequences as well as off-target analyses.
4,113 citations
TL;DR: In this article, the authors demonstrate a simple, low cost and effective approach of using the charging process in friction to convert mechanical energy into electric power for driving small electronics, which is fabricated by stacking two polymer sheets made of materials having distinctly different triboelectric characteristics, with metal films deposited on the top and bottom of the assembled structure.
4,069 citations
TL;DR: While nanorods with a higher aspect ratio along with a smaller effective radius are the best photoabsorbing nanoparticles, the highest scattering contrast for imaging applications is obtained from nanorod of high aspect ratio with a larger effective radius.
Abstract: The selection of nanoparticles for achieving efficient contrast for biological and cell imaging applications, as well as for photothermal therapeutic applications, is based on the optical properties of the nanoparticles. We use Mie theory and discrete dipole approximation method to calculate absorption and scattering efficiencies and optical resonance wavelengths for three commonly used classes of nanoparticles: gold nanospheres, silica−gold nanoshells, and gold nanorods. The calculated spectra clearly reflect the well-known dependence of nanoparticle optical properties viz. the resonance wavelength, the extinction cross-section, and the ratio of scattering to absorption, on the nanoparticle dimensions. A systematic quantitative study of the various trends is presented. By increasing the size of gold nanospheres from 20 to 80 nm, the magnitude of extinction as well as the relative contribution of scattering to the extinction rapidly increases. Gold nanospheres in the size range commonly employed (∼40 nm)...
4,065 citations
Authors
Showing all 45752 results
| Name | H-index | Papers | Citations |
|---|---|---|---|
| Zhong Lin Wang | 245 | 2529 | 259003 |
| Younan Xia | 216 | 943 | 175757 |
| Paul M. Thompson | 183 | 2271 | 146736 |
| Hyun-Chul Kim | 176 | 4076 | 183227 |
| Jiawei Han | 168 | 1233 | 143427 |
| John H. Seinfeld | 165 | 921 | 114911 |
| David J. Mooney | 156 | 695 | 94172 |
| Richard E. Smalley | 153 | 494 | 111117 |
| Vivek Sharma | 150 | 3030 | 136228 |
| James M. Tiedje | 150 | 688 | 102287 |
| Philip S. Yu | 148 | 1914 | 107374 |
| Kevin Murphy | 146 | 728 | 120475 |
| Gordon T. Richards | 144 | 613 | 110666 |
| Yi Yang | 143 | 2456 | 92268 |
| Joseph T. Hupp | 141 | 731 | 82647 |