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Government College

About: Government College is a based out in . It is known for research contribution in the topics: Population & Ring (chemistry). The organization has 4481 authors who have published 5986 publications receiving 57398 citations.


Papers
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Journal ArticleDOI
TL;DR: In this paper, the concept of group philicity (ωg) has been proposed to analyze intermolecular reactivity of some selected molecular systems and it can be found that DFT offers the possibility to calculate important functional group properties from the first principles in a non-empirical way.

204 citations

Journal ArticleDOI
TL;DR: Histopathological studies of the liver of different groups support the protective effects exhibited by the methanol extract of grape pomace by restoring the normal hepatic architecture and can be further extended to exploit its possible application for the preservation of food products as well as a health supplement and neutraceutical.
Abstract: Antioxidant-rich fractions were extracted from grape (Vitis vinifera) pomace using ethyl acetate, methanol, and water. The extracts were screened for their potential as antioxidants in different models. The ethyl acetate, methanol, and water extracts showed 76, 87.1, and 21.7% antioxidant activities at 100 ppm, respectively, using the 1,1-diphenyl-2-picrylhydrazyl model system. As the methanol extract of grape pomace showed maximum antioxidant activity among all of the extracts, it was selected to determine its effect on lipid peroxidation, hydroxyl radical scavenging activity, and human low-density lipoprotein (LDL) oxidation. The methanol extract showed 71.7, 73.6, and 91.2% inhibition using the thiobarbituric acid method, hydroxyl radical scavenging activity, and LDL oxidation, respectively, at 200 ppm. Treatment of albino rats of the Wistar strain with a single dose of CCl(4) at 1.25 mL/kg of body weight decreases the activities of catalase, superoxide dismutase (SOD), and peroxidase by 81, 49, and 89%, respectively, whereas the lipid peroxidation value increased nearly 3-fold. Pretreatment of the rats with the methanolic extract of grape pomace at 50 mg/kg (in terms of catechin equivalents) followed by CCl(4) treatment causes restoration of catalase, SOD, and peroxidase by 43.6, 73.2, and 54%, respectively, as compared with control, whereas lipid peroxidation was restored to values comparable with the control. Histopathological studies of the liver of different groups also support the protective effects exhibited by the methanol extract of grape pomace by restoring the normal hepatic architecture. Owing to this property, the studies on grape pomace can be further extended to exploit its possible application for the preservation of food products as well as a health supplement and neutraceutical.

199 citations

Journal ArticleDOI
A. V. Yadav, A. S. Shete, A. P. Dabke, P V Kulkarni1, S S Sakhare 
TL;DR: This article covers the advantages of co-crystals over salts, solvates (hydrates), solid dispersions and polymorphs, mechanism of formation of co,crystals, methods of preparation of co -crystals and application of co.crystals to modify physicochemical characteristics of active pharmaceutical ingredients along with the case studies.
Abstract: Crystal form can be crucial to the performance of a dosage form. This is especially true for compounds that have intrinsic barriers to drug delivery, such as low aqueous solubility, slow dissolution in gastrointestinal media, low permeability and first-pass metabolism. The nature of the physical form and formulation tends to exhibit the greatest effect on bioavailability parameters of water insoluble compounds that need to be given orally in high doses. An alternative approach available for the enhancement of drug solubility, dissolution and bioavailability is through the application of crystal engineering of co-crystals. The physicochemical properties of the active pharmaceutical ingredients and the bulk material properties can be modified, whilst maintaining the intrinsic activity of the drug molecule. This article covers the advantages of co-crystals over salts, solvates (hydrates), solid dispersions and polymorphs, mechanism of formation of co-crystals, methods of preparation of co-crystals and application of co-crystals to modify physicochemical characteristics of active pharmaceutical ingredients along with the case studies. The intellectual property implications of creating co-crystals are also highly relevant.

187 citations

Proceedings Article
01 Nov 2016
TL;DR: The use of digital information and controls technology to improve reliability, security, and efficiency of the electric grid.
Abstract: Development in the field of electronics and communication set up new paradigm. The need of making the grid smart is increasing due to environmental constrain and effective use of the available electricity. The use of digital information and controls technology to improve reliability, security, and efficiency of the electric grid.

186 citations

Journal ArticleDOI
TL;DR: In this article, the effect of MHD flow and heat transfer within a boundary layer flow on an upper-convected Maxwell (UCM) fluid over a stretching sheet is examined.
Abstract: In the present work, the effect of MHD flow and heat transfer within a boundary layer flow on an upper-convected Maxwell (UCM) fluid over a stretching sheet is examined. The governing boundary layer equations of motion and heat transfer are non-dimensionalized using suitable similarity variables and the resulting transformed, ordinary differential equations are then solved numerically by shooting technique with fourth order Runge–Kutta method. For a UCM fluid, a thinning of the boundary layer and a drop in wall skin friction coefficient is predicted to occur for higher the elastic number. The objective of the present work is to investigate the effect of Maxwell parameter β, magnetic parameter Mn and Prandtl number Pr on the temperature field above the sheet.

186 citations


Authors

Showing all 4481 results

NameH-indexPapersCitations
Rajesh Kumar1494439140830
Sanjeev Kumar113132554386
Rakesh Kumar91195939017
Praveen Kumar88133935718
V. Balasubramanian5445710951
Ghulam Murtaza53100514516
Marimuthu Govindarajan522126738
Muhammad Akram433937329
Ghulam Abbas404396396
Shivaji H. Pawar391684754
Muhammad Afzal381184318
Deepankar Choudhury351993543
Hidayat Hussain343165185
Hitesh Panchal341523161
Sher Singh Meena331873547
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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
202227
2021991
2020797
2019477
2018486
2017437