Institution
Griffith University
Education•Brisbane, Queensland, Australia•
About: Griffith University is a education organization based out in Brisbane, Queensland, Australia. It is known for research contribution in the topics: Population & Context (language use). The organization has 13830 authors who have published 49318 publications receiving 1420865 citations.
Topics: Population, Context (language use), Poison control, Health care, Tourism
Papers published on a yearly basis
Papers
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TL;DR: NAD depletion as pathogen response One way that plants respond to pathogen infection is by sacrificing the infected cells, and Toll/interleukin-1 receptor (TIR) domains cleave the metabolic cofactor nicotinamide adenine dinucleotide (NAD+) as part of their cell-death signaling in response to pathogens.
Abstract: SARM1 (sterile alpha and TIR motif containing 1) is responsible for depletion of nicotinamide adenine dinucleotide in its oxidized form (NAD+) during Wallerian degeneration associated with neuropathies. Plant nucleotide-binding leucine-rich repeat (NLR) immune receptors recognize pathogen effector proteins and trigger localized cell death to restrict pathogen infection. Both processes depend on closely related Toll/interleukin-1 receptor (TIR) domains in these proteins, which, as we show, feature self-association-dependent NAD+ cleavage activity associated with cell death signaling. We further show that SARM1 SAM (sterile alpha motif) domains form an octamer essential for axon degeneration that contributes to TIR domain enzymatic activity. The crystal structures of ribose and NADP+ (the oxidized form of nicotinamide adenine dinucleotide phosphate) complexes of SARM1 and plant NLR RUN1 TIR domains, respectively, reveal a conserved substrate binding site. NAD+ cleavage by TIR domains is therefore a conserved feature of animal and plant cell death signaling pathways.
326 citations
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TL;DR: Comparison between morphological tissues of the sampled plants found that roots consistently presented higher metal concentrations than either the stems or leaves, however unlike previous studies, this investigation revealed no consistent trend of stems accumulating more metals than the leaves.
326 citations
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University of Tartu1, Estonian Biocentre2, University of Cambridge3, Arizona State University4, University of California, Berkeley5, Armenian National Academy of Sciences6, Russian Academy of Sciences7, University of Auckland8, Pennsylvania State University9, University of Winchester10, Wellcome Trust Sanger Institute11, University of Copenhagen12, Bashkir State University13, Kazan Federal University14, Georgia Institute of Technology15, University of Pennsylvania16, Centre national de la recherche scientifique17, Eijkman Institute for Molecular Biology18, Massey University19, University of Dhaka20, Aarhus University21, Griffith University22, Josip Juraj Strossmayer University of Osijek23, Academy of Sciences of Uzbekistan24, Kuban State Medical University25, L.N.Gumilyov Eurasian National University26, Nazarbayev University27, North-Eastern Federal University28, Academy of Medical Sciences, United Kingdom29, Anthony Nolan30, University College London31, University of St Andrews32, University of Kharkiv33, International Burch University34, National Academy of Sciences of Belarus35, Radboud University Nijmegen36, King Abdullah University of Science and Technology37, Stanford University38, University of Arizona39, Stony Brook University40, University Hospital of North Norway41, Estonian Academy of Sciences42
TL;DR: A study of 456 geographically diverse high-coverage Y chromosome sequences, including 299 newly reported samples, infer a second strong bottleneck in Y-chromosome lineages dating to the last 10 ky, and hypothesize that this bottleneck is caused by cultural changes affecting variance of reproductive success among males.
Abstract: It is commonly thought that human genetic diversity in non-African populations was shaped primarily by an out-of-Africa dispersal 50-100 thousand yr ago (kya). Here, we present a study of 456 geographically diverse high-coverage Y chromosome sequences, including 299 newly reported samples. Applying ancient DNA calibration, we date the Y-chromosomal most recent common ancestor (MRCA) in Africa at 254 (95% CI 192-307) kya and detect a cluster of major non-African founder haplogroups in a narrow time interval at 47-52 kya, consistent with a rapid initial colonization model of Eurasia and Oceania after the out-of-Africa bottleneck. In contrast to demographic reconstructions based on mtDNA, we infer a second strong bottleneck in Y-chromosome lineages dating to the last 10 ky. We hypothesize that this bottleneck is caused by cultural changes affecting variance of reproductive success among males.
325 citations
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TL;DR: The great effect of structure engineering on the performance is discussed in depth, which will benefit the better design ofollow nanostructures to fulfill the requirements of specific applications and simultaneously enrich the diversity of the hollow nanostructure family.
Abstract: Hollow nanostructures have shown great promise for energy storage, conversion, and production technologies Significant efforts have been devoted to the design and synthesis of hollow nanostructures with diverse compositional and geometric characteristics in the past decade However, the correlation between their structure and energy-related performance has not been reviewed thoroughly in the literature Here, some representative examples of designing hollow nanostructure to effectively solve the problems of energy-related technologies are highlighted, such as lithium-ion batteries, lithium-metal anodes, lithium-sulfur batteries, supercapacitors, dye-sensitized solar cells, electrocatalysis, and photoelectrochemical cells The great effect of structure engineering on the performance is discussed in depth, which will benefit the better design of hollow nanostructures to fulfill the requirements of specific applications and simultaneously enrich the diversity of the hollow nanostructure family Finally, future directions of hollow nanostructure design to solve emerging challenges and further improve the performance of energy-related technologies are also provided
325 citations
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TL;DR: In this paper, the authors review the fundamentals of the Mg-H system and look at the recent advances in the optimisation of magnesium hydride as a hydrogen storage material through the use of catalytic additives, incorporation of defects and an understanding of the rate-limiting processes during absorption and desorption.
Abstract: Magnesium hydride has been studied extensively for applications as a hydrogen storage material owing to the favourable cost and high gravimetric and volumetric hydrogen densities. However, its high enthalpy of decomposition necessitates high working temperatures for hydrogen desorption while the slow rates for some processes such as hydrogen diffusion through the bulk create challenges for large-scale implementation. The present paper reviews fundamentals of the Mg–H system and looks at the recent advances in the optimisation of magnesium hydride as a hydrogen storage material through the use of catalytic additives, incorporation of defects and an understanding of the rate-limiting processes during absorption and desorption.
325 citations
Authors
Showing all 14162 results
Name | H-index | Papers | Citations |
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Rasmus Nielsen | 135 | 556 | 84898 |
Claudiu T. Supuran | 134 | 1973 | 86850 |
Jeffrey D. Sachs | 130 | 692 | 86589 |
David Smith | 129 | 2184 | 100917 |
Michael R. Green | 126 | 537 | 57447 |
John J. McGrath | 120 | 791 | 124804 |
E. K. U. Gross | 119 | 1154 | 75970 |
David M. Evans | 116 | 632 | 74420 |
Mike Clarke | 113 | 1037 | 164328 |
Wayne Hall | 111 | 1260 | 75606 |
Patrick J. McGrath | 107 | 681 | 51940 |
Peter K. Smith | 107 | 855 | 49174 |
Erko Stackebrandt | 106 | 633 | 68201 |
Phyllis Butow | 102 | 731 | 37752 |
John Quackenbush | 99 | 427 | 67029 |